Synaptic Transmission Flashcards
The synaptic cleft
small small space between post/pre synaptic neurons
Go steps of synapse
Action potential depolarizes Pre s membrane
Voltage gated Ca++ opens and enters axon terminal
Ca++ triggers Exotysis and neurotransmitter leave the cell
Neurotransmitters in the cleft binds and reacts with Post synaptic neuron
Stop steps of synapse
Neurotransmitter may be degraded by enzymes
Taken back by presynaptic neuron
Diffuses away
Rapid endocytosis
EPSP
involvemenrt
IPSP
chemical driving says go in, cell is more negative or an hyperpolarization
IPSP
No Change
Temporal Summation
Adding together of EPSP’s or IPSP’s generated by firing of the same presynaptic terminal at high frequency
Spatial Summation
Adding together of EPSP’s or IPSP’s generated by firing of two or more presynaptic neurons simultaneously.
IPSP works for my tricep and EPSP for my bicep
true
Presynaptic facilitation and inhibitation
If the combined signals of the EPSP and IPSPs reach - 55 then action potential is a go
The further you are away, the less diffusion
GPSP(Grand Postsynaptic Potential
summation of all