Synapses and Neurotransmitter Flashcards

1
Q

What is a synapse?

A

Functional connection between a neuron and the cell signaling

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2
Q

Neuromuscular junction

A

relationship between an neuron and muscle

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3
Q

Synapse in the CNS

A

second post another neuron

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4
Q

Synapse in the PNS

A

second postmuscle or gland

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5
Q

Presynaptic neuron is

A

the neuron signaling another neuron

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6
Q

Postsynaptic

A

The second neuron being signalled

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7
Q

Electrical synapses use

A

Gap Junctions

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8
Q

Chemical Synapses

A

Use neurotransmitter

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9
Q

Where do electrical synapses occur

A

in smooth muscle, cardiac, between neurons of the brain and glial cells.

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10
Q

In chemical synapses release a neurotransmitter from

A

the terminal buttons

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11
Q

What are cell adhesion proteins

A

pre and post synaptic cells are held together

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12
Q

release of a neurotransmitter (ca+)

A

Docking
Fusion
Exocytosis

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13
Q

Ca++ and synaptic vesicle docking

A

vesicles are docked to the plasma membrane by SNARE proteins

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14
Q

When Ca++ enter cell it binds to

A

synaptotagmin

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15
Q

What does synaptotagmin complex

A

displaces part of the snare which fuses the vesicle to the membrane so exocitosis happens

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16
Q

What is another word for Neurotransmitter

A

Ligand

17
Q

What is the action of the NT

A

to diffuse across the synapse where it binds to a specific receptor protein

18
Q

Excitatory Postsynaptic Potential (depolarization)

A

Opening Na+ or Ca++ channels

19
Q

Inhibitory Postsynaptic potetial (Hyperpolarization)

A

Opening K+ or Cl-

20
Q

EpSP

A

closer to threshold (depolarizes)

21
Q

IPSP

A

moves farther from threshold (hyperpolarizes)

22
Q

What is a summation of EpSp and IpSPs

A

Wether a AP occurs

23
Q

What is spatial summation

A

occurs due to convergence of signals into a single postsynaptic neuron

24
Q

What is temporal summation

A

due to successive waves of NT release over a short period of time

25
Q

What is convergence

A

several different presynaptic neurons (synapse on 1 postsynaptic neuron)

26
Q

What is divergence

A

axons have many branches so one presynaptic neuron can form synapses w/ several post synaptic neurons