synapses Flashcards
what is a synapse?
gaps between axon end of one neurone and dendrite of an adjacent neurone
how are synapses involved in action potentials?
the action potential is transmitted as a neurotransmitter which diffuses across a synapse
what does the axon terminal button contain?
- vesicles containing neurotransmitters
- neurotransmitter reuptake pump
- gated Ca2+ channels
why are impulses at synapses unidirectional?
- neurotransmitters are only released from presynaptic neurones
- receptors for neurotransmitters are only on post synaptic neurones
- so neurotransmitters can only activate action potentials in the post synaptic neurone
what is a neuromuscular junction?
the synapse between a motor nerve and a muscle
what is a sarcolemma?
plasma membrane which surrounds a muscle cell
what is the motor end plate?
the part of the sarcolemma which faces the synapse
how does transmission work at a neuromuscular junction?
- action potential reaches neuromuscular junction
- vesicles of acetylcholine fuse with presynaptic membrane
- acetylcholine diffuses across synapse and binds with receptors of post synaptic neurone
- allows Na+ to enter muscle which brings about contraction
what is divergence?
one neurone releases neurotransmitters to many neurones
what is convergence?
many neurones release neurotransmitters to one neurone
what is an excitatory post synaptic potential?
- action potential passes down axon to synapse
- causes a few vesicles to move and fuse with pre synaptic membrane
- small number of acetylcholine molecules produces small depolarisation
- alone not sufficient enough to cause action potential
what is summation?
the combined effect of several EPSPs to increase membrane depolarisation to reach threshold and cause action potential
what is spatial summation?
when two or more presynaptic neurones converge and release neurotransmitters at the same time onto the same post synaptic neurone
- small amount released from each can be enough altogether to reach threshold and trigger action potential
what is temporal summation?
when two or more nerve impulses arrive in quick succession from same presynaptic neurone
- action potential is more likely because more NT is released into synapse