synapses Flashcards

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1
Q

what is a synapse?

A

gaps between axon end of one neurone and dendrite of an adjacent neurone

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2
Q

how are synapses involved in action potentials?

A

the action potential is transmitted as a neurotransmitter which diffuses across a synapse

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3
Q

what does the axon terminal button contain?

A
  • vesicles containing neurotransmitters
  • neurotransmitter reuptake pump
  • gated Ca2+ channels
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4
Q

why are impulses at synapses unidirectional?

A
  • neurotransmitters are only released from presynaptic neurones
  • receptors for neurotransmitters are only on post synaptic neurones
  • so neurotransmitters can only activate action potentials in the post synaptic neurone
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5
Q

what is a neuromuscular junction?

A

the synapse between a motor nerve and a muscle

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6
Q

what is a sarcolemma?

A

plasma membrane which surrounds a muscle cell

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7
Q

what is the motor end plate?

A

the part of the sarcolemma which faces the synapse

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8
Q

how does transmission work at a neuromuscular junction?

A
  • action potential reaches neuromuscular junction
  • vesicles of acetylcholine fuse with presynaptic membrane
  • acetylcholine diffuses across synapse and binds with receptors of post synaptic neurone
  • allows Na+ to enter muscle which brings about contraction
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9
Q

what is divergence?

A

one neurone releases neurotransmitters to many neurones

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10
Q

what is convergence?

A

many neurones release neurotransmitters to one neurone

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11
Q

what is an excitatory post synaptic potential?

A
  • action potential passes down axon to synapse
  • causes a few vesicles to move and fuse with pre synaptic membrane
  • small number of acetylcholine molecules produces small depolarisation
  • alone not sufficient enough to cause action potential
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12
Q

what is summation?

A

the combined effect of several EPSPs to increase membrane depolarisation to reach threshold and cause action potential

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13
Q

what is spatial summation?

A

when two or more presynaptic neurones converge and release neurotransmitters at the same time onto the same post synaptic neurone
- small amount released from each can be enough altogether to reach threshold and trigger action potential

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14
Q

what is temporal summation?

A

when two or more nerve impulses arrive in quick succession from same presynaptic neurone
- action potential is more likely because more NT is released into synapse

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