Synapse / Neurotransmission Flashcards
A region where impulses are transmitted from one neuron to the another is known as?
The synapse
What is a neuromuscular Junction?
This is a connection when a neuron terminates on a muscle.
What is known as the region where the neuron communicates with the effector organ?
Neuroeffector junction
What type of neurotransmission occurs between skeletal muscles , smooth muscles and cardiac muscles?
Skeletal- Stereotypical cholinergic neurotransmission
Smooth & Cardiac muscles- Diffuse neurotransmission
What is the function of the dendrite?
The dendrites function as a major site that receives electrical signals from other neurons, processes these signals, and transfers the information to the soma of the neuron.
What is the normal width of the synaptic cleft?
20-40nm wide
What is the postsynaptic density?
The postsynaptic density is an ordered complex of specific receptors, binding proteins, and enzymes induced by postsynaptic effects.
What are the type of synaptic vesicles?
Small clear synaptic vesicles- contains Acetylcholine, GABA, glycine or glutamate (flattened).
Small dense core vesicles- catecholamines (nor epinephrine, epinephrine, dopamine,seotonin)
Large dense core vesicles - neuropeptides
The vesicles and the proteins contained within them are synthesized in the neuronal cell body and transported along the axon to the endings by?
Fast axoplasmic transport
What is the motor unit?
The number of myofibres innervated by the single motor neurone.
What is the motor end plate?
This is the specialized portion on the sarcolemma that is being innervated.
What are the benefits of acetylcholine ?
They increase your memory
Increases Arousal
And increase in Analgesia(the inability to feel pain)
The terminal ending fits into a depression of the muscle membrane which is thrown into folds called?
Palisades
True of false? Cholinergic transmission is sodium dependent?
FALSE!! It is Calcium Ca2+ dependent