Synapse Flashcards
method by which two neurons communicate with each other. Involves chemical transmission (occurs less quickly)
Synaptic transmission
regions between neurons or between neurons & effectors
Synapse/synaptic cleft
Synapse between the axon terminal of the motor neuron & muscle/gland.
Neuromuscular junction
carries impulse to the synapse
presynaptic neuron
carries impulse away from the synapse
postsynaptic neuron
effect produced by the accumulation of transmitter chemicals from 2 or more neurons
Summation
common neurotransmitter that is released by endplates of presynaptic neurons & diffuses across the synapse to receptors on postsynaptic neuron
Acetylcholine
An enzyme released shortly after acetylcholine to limit its action by breaking it down
Cholinesterase
incoming action potential in the pre-synaptic neuron causes Ca2+ channels to open which…
Step 1 in events at the synapse
…causes the vesticles containing neurotrasmitter molecules to fuse with membrane
Step 2 in events at the synapse
Vesticles then release neurotransmitters(by exocytosis) into synaptic cleft where they diffuse across to postsynaptic neuron
Step 3 in events at the synapse
Neurotransmitter binds to a receptor & opens a chemically-gated ion channel
Step 4-5 in events at the synapse
With the channel open, ions (Na+) diffuse into the post-synaptic neuron and initiates action potentail & signal is successfully passed on
Step 6 in events at the synapse
Neurotransmitter is broken down.This ensures tha tthe neurotransmitter’s effects is brief & precise. Neurotransmitter molecules can be recycled or diffuse away(Reuptake)
Step 7 in events at the synapse
Increases the permeability of post-synaptic neuron to Na+, moving it closer to threshold and making it more likely to fire.
Excitatory