Sympathomimetics: Direct

Question 1

Epinephrine

Answer 1

B > a

Uses: anaphylaxis, open angle glaucoma, asthma, hypoTN, a effects dominate at high doses.

Question 2

Norepinephrine

Answer 2

a1 > a2 > B1

Uses: hypoTN, but decreases renal perfusion

Question 3

Isoproterenol

Answer 3

B1 = B2

Uses: Electrophysiologic evaluation of tachyarrhythmias. Can worsen ischemia.

Question 4

Dopamine

Answer 4

D1 = D2 > B > a

Uses: Unstable bradychardia, heart failure, shock; alpha effects dominate at high doses.

Question 5

Dobutamine

Answer 5

B1 > B2, a

Uses: Heart failure (inotropic > chronotropic), cardiac stress test

Question 6

Phenylphrine

Answer 6

a1 > a2

Question 7

Albuterol, salmeterol, terbutaline

Answer 7

B2 > B1

Uses: Albuterol for acute asthma; salmeterol for long-term asthma or COPD control; terbutaline to reduce premature uterine contractions