Muscarinic Antagonists

Question 1

Atropine, homatropine, tropicamide

Answer 1

Organ: Eye

Produces mydriasis and cycloplegia (loss of accommodation bc of paralysis of ciliary muscles)

Question 2

Benztropine

Answer 2

Organ: CNS

Tx for PD

Question 3

Scopolamine

Answer 3

Organ: CNS

Motion sicknes

Question 4

Ipratropium, tiotropium

Answer 4

Organ: Respiratory

COPD, asthma (“I PRAy to breath soon.”)

Question 5

Oxybutynin, darifenacin, solifenacin, tolterodine, fesoterodine, trospium

Answer 5

Organ: GU

Reduce urgency in mild cystitis and reduce bladder spasms.

Question 6

Glycopyrrolate

Answer 6

Organ: GI, repiratory

Parenteral: Preop to reduce airway secretions

Oral: drooling, peptic ulcer

Question 7

Atropine

Answer 7

Organ: Lots

Used to treat bradychardia and for ophthalmic applications.

“Hot as a hare, Dry as a bone, Red as a beet, Blind as a bat, Mad as a hatter.”