Sympathomimetics Flashcards

1
Q

Symathomimetics involve _________ occurring, __________, _______ ___ catecholamines.

A

naturally, synthetic, synthetic non

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2
Q

Synthetic Non-catecholamine can be _______ and ______ acting.

A

indirect, direct

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3
Q

What are the pharmacologic effects of sympathomimetic will have on vasoconstriction:

A

-Cutaneous and renal circulations

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4
Q

What are the pharmacologic effects of sympathomimetic will have on vasodilation:

A

-Skeletal muscle

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5
Q

Sympathomimetic cause what effect in the lungs:

A

-Bronchodilation

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6
Q

What are the pharmacologic effects of sympathomimetic will have on Cardiac Stimulation:

A
  • Increased heart rate
  • Increased myocardial contractility
  • Vulnerability to dysrhythmias
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7
Q

What are the pharmacologic effects of sympathomimetic will have hepatically:

A

-Glycogenolysis

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8
Q

T/F: Sympathomimetic will cause liberation of free fatty acids from adipos tissue:

A

True

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9
Q

What pharmacologic effects will sympathomimetics have on modulation of hormone secretion:

A
  • insulin
  • Renin
  • Pituitary
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10
Q

T/F: Sympathomimetics does not cause CNS stimulation.

A

False

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11
Q

Sympathomimetic are most ofter used clinically for:

A
  • Positive inotropes

- Elevate blood pressure (Vasopressors)

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12
Q

Less common uses for sympathomimetics are:

A
  • Bronchospasm (asthmatic patient)
  • Anaphylaxis
  • Prevent local anesthetic absorption from site of injection or infiltration
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13
Q

T/F: All sympathomimetic are derived from B phenylethylamine.

A

True

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14
Q

__________ of hydroxyl groups on the 3 and 4 position of the _______ ring of the B phenylethylamine creates a catachol.

A

Presence, benzene

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15
Q

What are the sympathetic receptor selectivity for sympathomimetic:

A
  • B1
  • B2
  • A1
  • A2
  • Dompamine 1
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16
Q

B1 receptor of sympathetic receptor for sympathomimetic works on:

A

-Myocardial stimulation

17
Q

B2 receptor of sympathetic receptor for sympathomimetic works on:

A

RELAXATION

  • Bronchial
  • vascular smooth muscle
  • Uterine relaxation
18
Q

A1 receptor of sympathetic receptor for sympathomimetic works on:

A

-Blood vessel constriction

19
Q

A2 receptor of sympathetic receptor for sympathomimetic works on:

A

-Postganglionic presynaptic inhibition of norepinephrine release

20
Q

Dopamine 1 receptor of sympathetic receptor for sympathomimetic works on:

A

-Renal artery dilatation

21
Q

What is the mechanism of action for sympathomimetic:

A

.