Sympathomimetics Flashcards
Symathomimetics involve _________ occurring, __________, _______ ___ catecholamines.
naturally, synthetic, synthetic non
Synthetic Non-catecholamine can be _______ and ______ acting.
indirect, direct
What are the pharmacologic effects of sympathomimetic will have on vasoconstriction:
-Cutaneous and renal circulations
What are the pharmacologic effects of sympathomimetic will have on vasodilation:
-Skeletal muscle
Sympathomimetic cause what effect in the lungs:
-Bronchodilation
What are the pharmacologic effects of sympathomimetic will have on Cardiac Stimulation:
- Increased heart rate
- Increased myocardial contractility
- Vulnerability to dysrhythmias
What are the pharmacologic effects of sympathomimetic will have hepatically:
-Glycogenolysis
T/F: Sympathomimetic will cause liberation of free fatty acids from adipos tissue:
True
What pharmacologic effects will sympathomimetics have on modulation of hormone secretion:
- insulin
- Renin
- Pituitary
T/F: Sympathomimetics does not cause CNS stimulation.
False
Sympathomimetic are most ofter used clinically for:
- Positive inotropes
- Elevate blood pressure (Vasopressors)
Less common uses for sympathomimetics are:
- Bronchospasm (asthmatic patient)
- Anaphylaxis
- Prevent local anesthetic absorption from site of injection or infiltration
T/F: All sympathomimetic are derived from B phenylethylamine.
True
__________ of hydroxyl groups on the 3 and 4 position of the _______ ring of the B phenylethylamine creates a catachol.
Presence, benzene
What are the sympathetic receptor selectivity for sympathomimetic:
- B1
- B2
- A1
- A2
- Dompamine 1