Quiz 4 Local Anesthetics 2nd. Flashcards
Drugs that reversibly block the conduction of electrical impulses along nerve fibers are called?
Local Anesthetics
Removal of the ______ _________ is followed by spontaneous and complete return of nerve conduction, with no evidence of structural damage to nerve fibers.
local anesthetics
The ability of the local anesthetic to work is dependent on what factors?
- physiochemical properties of the local anesthetic
- Anatomy of the verve being blocked
What part of the nerve does a schwann cell sheath wrap around?
Axon
What is a node of ravier?
Located on the axon between two schwann cell sheaths.
What is the resting membrane potential of a peripheral nerve?
-70 mV
When a resting nerve is activated the membrane potential is ________.
Reversed
The influx of what electrolyte during the depolarization of a nerve?
Na+
What is the mechanism of action that restores a nerve back to the resting membrane potential?
Na/K ATPase pump 3:2 ratio
Once this process has reversed the membrane potential to ______mV, an outward __________ ___________ develops and begins to resist the inward diffusion of ____.
+35, electrochemical gradient, Na+
What electrolyte is pumped back into the nerve cell to restore the nerve resting membrane potential
K
What is hyperpolarization of a nerve cell?
When the membrane potential is < - 70 mV.
What is the refractory period?
A time frame when there can be no depolarization of a cell.