Sympathetic NS and Immunity

Question 1

The _____ and the _________ are the two major adaptive systems of the body

Answer 1

brain and immune system

Question 2

During an immune response the brain and the immune system __________ and this process is essential for maintaining homeostasis.

Answer 2

“talk to each other”

Question 3

Two major pathway systems are involved in this cross-talk between the brain and the immune system, what are they?

Answer 3

The hypothalamic-pituitary-adrenal (HPA) axis
and
The sympathetic nervous system (SNS)

Question 4

Evidence accumulated over the last 20 years suggests that what neurotransmitter fulfills the criteria for neurotransmitter/neuromodulator in lymphoid organs

Answer 4

norepinephrine (NE)

Question 5

Thus, primary and secondary lymphoid organs receive extensive __________ innervation

Answer 5

sympathetic/noradrenergic

Question 6

Subluxation _______ brain / cortical summation.

Answer 6

reduces

**Reduced brain summation dis-inhibits the sympathetic nervous system

Question 7

Reduced brain summation dis-inhibits the sympathetic nervous system. Hence, the sympathetic nervous system is chronically ________, releasing more catecholamines:

Answer 7

overactive

Question 8

• norepinephrine is released from the _________,

- epinephrine is released from the __________

Answer 8

post-ganglionic sympathetic efferents

Adrenal Medulla

Question 9

This increase in sympathetically-derived catecholamines reduces the systemic type 1 (Th1) immune system response causing a shift to __________

Answer 9

Th2 Immune Response

Question 10

The most extensive and physiologically most diverse component of the efferent nervous system is the____________, which sends axons to all parts of the body

Answer 10

sympathetic nervous system (SNS)

Question 11

T or F
The sympathetic fibers also control blood flow to these immune organs which may influence Lymphocyte traffic and therefore immune cell responses.

Answer 11

T

Question 12

The ______ provides the major integrative and regulatory role between the CNS and the immune system

Answer 12

SNS

Question 13

T or F
Correcting the subluxation will: Increase sympathetic activity, Increase catecholamine release, Inhibit the Th1
response which will improve infection fighting; and Enhance the Th2 response, which will reduce allergy /atopicdisease signs and symptom

Answer 13

F
All Backwards Should read

Correcting the subluxation will: reduce sympathetic activity, reduce catecholamine release, enhance the Th1
response which will improve infection fighting; and inhibit the Th2 response, which will reduce allergy /atopic
disease signs and symptoms