Sweatman Autonomic Pharmacology: receptor distribution

Question 1

Sympathetic action on iris RADIAL muscle

Answer 1

contracts–>alpha 1

Question 2

sympa action on iris Circular muscle

Answer 2

NONE

Question 3

PS action on Iris radial muscle

Answer 3

none

Question 4

PS action on iris circular muscle

Answer 4

contracts–>M3

Question 5

Symp action on Ciliary muscle of the eye

Answer 5

relaxes–> Beta

Question 6

PS activity on ciliary muscle of the eye

Answer 6

contracts–> M3

Question 7

Sympa action on SA NODE, Ectopic Pacemakers, CONTRACTILITY

Answer 7

ACCELERATES, ACCELERATES AND INCREASES–> BETA 1 AND BETA 2

Question 8

PS ACTION ON SA NODE

Answer 8

DECELERATES–> M2

Question 9

PS ACTION ON CONTRACTILITY OF THE HEART

Answer 9

DECREASEC (ATRIA)–> M2

Question 10

PS INNERVATION TO BLOOD VESSELS

Answer 10

NONE–except for endothelium of the heart

Question 11

Sympathetic action on skin, splanchnic vessels

Answer 11

contracts–> alpha

Question 12

sympa action on skeletal muscle BV’s

Answer 12

relaxes–> beta 2

(contracts) –>alpha
* ***relaxes–> M3

Question 13

vascular smooth muscle in skeletal muscle has what time of fibers

Answer 13

sympathetic CHOLINERGIC dilator (relaxing) fibers

Question 14

sympa to endothelium of vessels in the heart, brain, and viscera

Answer 14

NONE

Question 15

PARAsympathetic to endothelium of vessels in the heart, brain, and viscera

Answer 15

synthesizes and released EDRF–> M3, M5

Question 16

Endothelium of most blood vessels releases what?

Answer 16

Endothelium derived relaxing factor–> a potent vasodilator

Question 17

EDRF is released in response to____

Answer 17

Muscarinic stimuli

Question 18

Sympathetic action on BRONCHIOLAR smooth muscle

Answer 18

relaxes–> beta 2

Question 19

parasympathetic action on bronciolar smooth muscle

Answer 19

contracts–> m3

Question 20

Wheezing in asthma is what?

Answer 20

parasympathetic activation of M3 causing bronchiolar smooth muscle to contrast causing spasms

Question 21

SYMPATHETIC action on SMOOTH MUSCLE WALLS of GI tract

Answer 21

relaxes–> alpha 2 and beta 2 (probably through presynaptic inibition of PS activity)

Question 22

Sympathetic action to GI tract sphincters

Answer 22

contracts–> alpha 1

*sympathetic tone

Question 23

Smpathetic action on GI tract secretion

Answer 23

none–> remember in sympathetic responses we shift away from secretion/digestion to fight or flight

Question 24

PS action on GI smooth muscle walls

Answer 24

CONTRACTS–> M3

*PROBABLY FOR PERISTALSIS

Question 25

PS ACTION ON GI TRACTS SPHINCTERS

Answer 25

RELAXES--> M3

Question 26

PS ACTION ON GI SECRETION

Answer 26

INCREASES-->M3--> REST AND DIGEST

Question 27

SYMPATHETIC action on GU smooth muscle: Bladder Wall

Answer 27

relaxes--> beta 2

Question 28

SYMPATHETIC action on GU smooth muscle: | Sphincter

Answer 28

contracts--> alpha 1

Question 29

SYMPATHETIC action on GU smooth muscle: uterus, pregnant

Answer 29

relaxes-->beta 2 | contracts--> alpha

Question 30

SYMPATHETIC action on GU smooth muscle: penis, seminal vesicles

Answer 30

ejaculation--> alpha1

Question 31

PAPASYMPATHETIC action on GU smooth muscle: Bladder Wall

Answer 31

contracts M3

Question 32

PARASYMPATHETIC action on GU smooth muscle: Sphincter

Answer 32

relaxes M3

Question 33

PARASYMPATHETIC action on GU smooth muscle: Uterus, pregnant

Answer 33

NONE

Question 34

SYMPATHETIC action on GU smooth muscle: penis, seminal vesicles

Answer 34

erection-->M

Question 35

post synaptic parasympathetic neurons for the most part release _____ onto _____

Answer 35

acetylcholine onto muscarinic acetyl choline receptors

Question 36

post synaptic sympathetic neurons for the most part release ____ onto ______

Answer 36

epinephrine.norepinephrine onto alpha and beta adrenergic receptors

Question 37

SYMPATHETIC action on pilomotor smooth muscle

Answer 37

CONTRACTS--> ALPHA

Question 38

SYMPATHETIC action on Eccrine Sweath Glands

Answer 38

increases--> MUSCARINIC

Question 39

SYMPATHETIC action on Appocrine sweath glands (stress)

Answer 39

increases sweat--> alpha

Question 40

PARASYMPATHETIC action on SKIN

Answer 40

NONE | *so none to either type of sweat glands or pilomotor smooth muscle

Question 41

Sympathetic action on liver

Answer 41

stimulates gluconeogenesis--> beta 2 and alpha | stimulates glycogenolysis--> beta 2 and alpha

Question 42

Sympathetic action on fat cells

Answer 42

lipolysis--> beta 3

Question 43

sympathetic action on kidneys

Answer 43

renin release--> beta 1

Question 44

Parasympathetic action on liver regarding metabolism

Answer 44

NONE

Question 45

Parasympathetic action on kidney regarding metabolism

Answer 45

NONE

Question 46

Parasympathetic action on fat cells regarding metabolism

Answer 46

NONE

Question 47

Alpha 1 blockers action on GU smooth muscle will

Answer 47

prevent ejaculation