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CMOD > Sweatman Autonomic Pharmacology: receptor distribution > Flashcards

Sweatman Autonomic Pharmacology: receptor distribution Flashcards

1
Q

Sympathetic action on iris RADIAL muscle

A

contracts–>alpha 1

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2
Q

sympa action on iris Circular muscle

A

NONE

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3
Q

PS action on Iris radial muscle

A

none

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4
Q

PS action on iris circular muscle

A

contracts–>M3

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5
Q

Symp action on Ciliary muscle of the eye

A

relaxes–> Beta

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6
Q

PS activity on ciliary muscle of the eye

A

contracts–> M3

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7
Q

Sympa action on SA NODE, Ectopic Pacemakers, CONTRACTILITY

A

ACCELERATES, ACCELERATES AND INCREASES–> BETA 1 AND BETA 2

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8
Q

PS ACTION ON SA NODE

A

DECELERATES–> M2

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9
Q

PS ACTION ON CONTRACTILITY OF THE HEART

A

DECREASEC (ATRIA)–> M2

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10
Q

PS INNERVATION TO BLOOD VESSELS

A

NONE–except for endothelium of the heart

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11
Q

Sympathetic action on skin, splanchnic vessels

A

contracts–> alpha

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12
Q

sympa action on skeletal muscle BV’s

A

relaxes–> beta 2

(contracts) –>alpha
* ***relaxes–> M3

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13
Q

vascular smooth muscle in skeletal muscle has what time of fibers

A

sympathetic CHOLINERGIC dilator (relaxing) fibers

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14
Q

sympa to endothelium of vessels in the heart, brain, and viscera

A

NONE

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15
Q

PARAsympathetic to endothelium of vessels in the heart, brain, and viscera

A

synthesizes and released EDRF–> M3, M5

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16
Q

Endothelium of most blood vessels releases what?

A

Endothelium derived relaxing factor–> a potent vasodilator

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17
Q

EDRF is released in response to____

A

Muscarinic stimuli

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18
Q

Sympathetic action on BRONCHIOLAR smooth muscle

A

relaxes–> beta 2

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19
Q

parasympathetic action on bronciolar smooth muscle

A

contracts–> m3

20
Q

Wheezing in asthma is what?

A

parasympathetic activation of M3 causing bronchiolar smooth muscle to contrast causing spasms

21
Q

SYMPATHETIC action on SMOOTH MUSCLE WALLS of GI tract

A

relaxes–> alpha 2 and beta 2 (probably through presynaptic inibition of PS activity)

22
Q

Sympathetic action to GI tract sphincters

A

contracts–> alpha 1

*sympathetic tone

23
Q

Smpathetic action on GI tract secretion

A

none–> remember in sympathetic responses we shift away from secretion/digestion to fight or flight

24
Q

PS action on GI smooth muscle walls

A

CONTRACTS–> M3

*PROBABLY FOR PERISTALSIS

25
Q

PS ACTION ON GI TRACTS SPHINCTERS

A

RELAXES–> M3

26
Q

PS ACTION ON GI SECRETION

A

INCREASES–>M3–> REST AND DIGEST

27
Q

SYMPATHETIC action on GU smooth muscle: Bladder Wall

A

relaxes–> beta 2

28
Q

SYMPATHETIC action on GU smooth muscle:

Sphincter

A

contracts–> alpha 1

29
Q

SYMPATHETIC action on GU smooth muscle: uterus, pregnant

A

relaxes–>beta 2

contracts–> alpha

30
Q

SYMPATHETIC action on GU smooth muscle: penis, seminal vesicles

A

ejaculation–> alpha1

31
Q

PAPASYMPATHETIC action on GU smooth muscle: Bladder Wall

A

contracts M3

32
Q

PARASYMPATHETIC action on GU smooth muscle: Sphincter

A

relaxes M3

33
Q

PARASYMPATHETIC action on GU smooth muscle: Uterus, pregnant

A

NONE

34
Q

SYMPATHETIC action on GU smooth muscle: penis, seminal vesicles

A

erection–>M

35
Q

post synaptic parasympathetic neurons for the most part release _____ onto _____

A

acetylcholine onto muscarinic acetyl choline receptors

36
Q

post synaptic sympathetic neurons for the most part release ____ onto ______

A

epinephrine.norepinephrine onto alpha and beta adrenergic receptors

37
Q

SYMPATHETIC action on pilomotor smooth muscle

A

CONTRACTS–> ALPHA

38
Q

SYMPATHETIC action on Eccrine Sweath Glands

A

increases–> MUSCARINIC

39
Q

SYMPATHETIC action on Appocrine sweath glands (stress)

A

increases sweat–> alpha

40
Q

PARASYMPATHETIC action on SKIN

A

NONE

*so none to either type of sweat glands or pilomotor smooth muscle

41
Q

Sympathetic action on liver

A

stimulates gluconeogenesis–> beta 2 and alpha

stimulates glycogenolysis–> beta 2 and alpha

42
Q

Sympathetic action on fat cells

A

lipolysis–> beta 3

43
Q

sympathetic action on kidneys

A

renin release–> beta 1

44
Q

Parasympathetic action on liver regarding metabolism

A

NONE

45
Q

Parasympathetic action on kidney regarding metabolism

A

NONE

46
Q

Parasympathetic action on fat cells regarding metabolism

A

NONE

47
Q

Alpha 1 blockers action on GU smooth muscle will

A

prevent ejaculation

CMOD (19 decks)

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