SW - Microbiomes and One Health II Flashcards

1
Q

What is the Urban Microbiome? (3)

A
  • Study of microorganisms in built environments (buildings, cities).
  • Ranges from small-scale (e.g., office keyboards) to large-scale (e.g., entire cities).
  • Focuses on understanding presence and potential impact.
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2
Q

How can the Urban Microbiome impact future design? (3)

A

Infection Prevention and Control:
* Assessing risk in healthcare settings.
* Balancing sanitation with maintaining healthy microbiomes.

Public Spaces:
* Understanding microbial composition in homes and public areas.
* Avoid over-sanitisation to protect beneficial microbes.

Ecosystem Approach:
* Recognising interconnectedness of humans, life forms, and built environments.
* Designing spaces that support healthy ecosystems, including microbial ones.

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3
Q

What role does the Built Environment play in hospital infections? (4)

A
  • Crucial for Infection Prevention and Control.
  • Public expects hospitals to be clean and safe.
  • Studies show hospital ward designs can contribute to infections (e.g., C. difficile).
  • Pathogens survive on surfaces, influenced by surface type and cleaning agents.
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4
Q

What is the history of Infection Prevention and Control (IPC)? (4)

A
  • Started in the 1950s due to staphylococcal infections.
  • Institutionalised in the 1970s with hospital programs.
  • Modern IPC is regulated, monitored, and specialised.
  • Pandemics increased public awareness of IPC.
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5
Q

Why do outbreaks persist despite IPC efforts? (4)

A

Microbiome Analysis: Reveals persistent microbial communities in built environments.

Dry Surface Biofilms:
* Emerging field, first described in 2015.
* Difficult to detect and harbour resistant microorganisms.
* Found on disinfected ICU surfaces (>90%, Ledwoch et al., 2022).

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6
Q

What is Sick Building Syndrome (SBS)? (4)

A
  • Complex condition with varied symptoms (e.g., headaches, respiratory issues, fatigue).
  • Linked to indoor occupations, not just poor cleaning or ventilation.
  • Tied to building materials and disproportionately affects women.
  • Potential link to microbial communities in buildings (Bosch et al., 2024).
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7
Q

What are some characteristics of SBS? (5)

A
  • Tends to be linked to indoor occupations but can also occur in homes.
  • Not solely controlled by cleaning or ventilation.
  • Linked to a wide range of building materials.
  • Disproportionately affects or is reported by women.
  • Can be linked to specific work/job types and has historical and social aspects
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8
Q

What is the concept of Healthy Porosity? (3)

A
  • Refers to balancing exposure to natural elements and indoor environments.
  • Humans are the main source of microbial colonisers in sealed buildings.
  • Bosch et al. (2024) introduced the concept to promote healthier interactions.
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9
Q

How is Microbiome Research shaping urban design? (3)

A
  • One Health Approach: Considers interconnectedness of human, animal, and environmental health.
  • Microbiome-Informed Design: Guides architects to incorporate microbiome knowledge.
  • Creating Healthy Microbial Worlds: Urban planning prioritises environments that benefit human health.
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10
Q

What is Microbiome-Inspired Green Infrastructure (MIGI)? (5)

A

Multi-functional green infrastructure promoting beneficial microbial interactions.

Components:
* Aerobiome: Microbes in air, influenced by plants and environment.
* Phyllosphere Microbiome: Microbes on plant surfaces, improving air quality.
* Rhizosphere Microbiome: Soil microbes critical for plant growth.
* Human/Animal Microbiome: Microbes influencing health and well-being.

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11
Q

What are some benefits of MIGI? (4)

A
  • Improved air quality
  • Enhanced biodiversity
  • Reduced urban heat island effect
  • Potential health benefits for humans
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12
Q

What are some futuristic ideas in Urban Design? (3)

A
  • Air Quality: Focus on improving air quality via resources like the Aerobiome website.
  • Probiotic Cities: Robinson et al. (2024) propose integrating nature-based solutions.
  • Future Architecture: Photosynthetica showcases designs blending nature and urban spaces.
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