Sux Flashcards
1
Q
duration of Sux
A
10 mts.
2
Q
relative overdose is usally administered
A
reason for rapid onset of action
3
Q
low lipid solubility
A
small Vol of distribution
4
Q
pseudochoinestrase
A
rapidly metabolized in circulation.
5
Q
rapidly met in circulation , significance
A
only small fraction of the injected enters circulation
6
Q
hypothermia causes
A
prolong psudoche duration
7
Q
aberrentvpsudocholinestrase, reduced level , pregnanacy, liv disease v
A
prolog duration
8
Q
liver diz,vpregnanacy , prolong how long
A
by 2-20 min
9
Q
prolong by heterozygote enz 1/ 25-30
A
20- 30 min
10
Q
homozy enz one in 3000
A
4-8 hours
11
Q
enzyme w 1/100 affinity for Sux
A
Dibucaine resist allelle
12
Q
a local anesthetic inhibits normal psudocholin by 80% but inhib 20% in atypicalvenzyne
A
Dibucaine no
13
Q
TX of prolong paraly
A
Mech vven and sedation
