Cisatracurium Flashcards
CA is less potent than A
CA is x4 potent than A ,
Potency /CA/A
Like A , CA undergoes degrdn in Plasma at phy Ph and temp by organ depdt hofmann elim
Non organ depdt
CA/A/Elimination MOA
CA metblte Laudanosin &acrylate has major effect on NMJ
CA is very potent. So LA dont hav any effct.
CA - Laudanosine - potency- effcet of metabolite
CA inj 0.1- 0.15mg/kg produc good intubation condition w long DOA
intermed DOA
Dosage CA - DOA – for good intub dose.
Like A , CA produces dose dep inc in Histamine
CA = A = Histamine releas =
unlike A, CA is not dose dep histamine relesas
CA produces dose depnd inc in HR, BP and autonomic changes.
unlike A, CA does not produce dose dep inc or aut changes.
CA - A- Autonom changes = effect on CVS