sus2,3 Flashcards
how does controlled fluctation work
use of suspending agent that is hydrophillic as a polymer that bind to particles and adsorbes on them it can bind to multiple particle till it form bridges that is critical concentration the ain is to go higher and cease bridging and cause particle seperation by hinderance
what affects the ability of suspending agent
the affinity for the protein surface, charge, size and orientation of polymer.
what is important about ionic surfectants
work same way as counterions but have to ensure not go over cmc or solubilisation will occure and also work by deffloculation and steric hinderance
how do we delay caking
we can’t affect the density or gravity but we can affect particle size increase brownian motion and increase diffusion and increase free energy and less likely to cake and increase viscosity by use of suspending agent to decrease sedimentation rate
rheological consideration
use of non-newtonian fluid with shear thinning properties with thixotherapy advantageous
pseudoplastic
rest high viscosity to inhibit sendimentation
shaking move fluid allowing redispersion of any sediment
plastic flow w thixotherapy
yield value at rest behave like a solid after yield viscosity reduces allowing redispersion thixo allows time to pour