gels Flashcards
gels
semi-rigid systems where the gelling agents forms a 3-d network interpenterated by the dispersing vehicle. Movement of the vehicle is restricted by the network. increasing viscosity and becoming semi-solid. transparent or translucent
formed by flocculation of lyophobic solids or concentrated solution of lyophilic colloids
what is the basing format
aqueous but can be hydrocarbon based also xerogels are bases which water has been removed from
syneresis
squeezing out of vehicle on storage caused by the contraction of elastic gel network
sweling
absorption of liquid by gel with an increase in v
imbibition
absorptions of liquid without noticeable increase in volume
advantages of gels
Ramaleh
disadvantages
specific method, incompatibilities and preservation and sterilisation required for hydrogel
what are the classification of gels based on structure
two phase; gel mase contains a network of small discrete network of particles flocculation
single phase; macromolecules uniformly distributed
throughout a liquid. Long flexible molecular chains that are entangled and bound together by primary or secondary valence forces. No apparent boundaries exist between the two
what are classification of gels based on contineous phase
hydrogel; aquous phase with natural or synthetic polymer
organeogels; hydrocarbon, veg or animal oil as base
what are classification of gels based on reversibility
1- irreversible gel. 3D network of covalent bonds that swell up in presence of water but not dissolve
2- reversible gel; bond weaker VDw