Surgucal Infection Amd Choice Of Antibiotic Flashcards
What is a surgical infection
An infection whose resolution would require surgery or invasive procedures for cure
What is Rational use of antibiotics
It is the use of an antibiotic which is clinically best suited for the patient, at a an adequate dosage best fro the patient for a duration of time and at a cost that is affordable for the patient and their community
What is an Ideal antibiotic
Specific and effective to organism
Bacterial action is more at the site of action
Antibacterial effect is not affected by body fluids, plasma, enzymes,
Several routes of administration
Appreciable cost
Minimal Toxicity
Slow development f résistance
Empirical Therapy
Is therapy based on experience and, more specifically, therapy begun on the basis of a clinical educated guess in the absence of complete or perfect information or
Giving antibiotics without identification and sensitivity test of bacteria.
However specimen should be obtained before giving antibiotics.
Its based on local epidemiological data
Definitive treatment
The treatment plan for a disease that has been chosen as the best one for a patient after all other choices have been considered.
It is the most effective, least toxic and has narrowest selection
Definitive Therapy is dependent on
Identification and Sensitivity
Indications for empirical therapy
Infection of unknown origin
Neutropenia patients
Symptoms of meningitis
Examples of abuse of antibiotics
Treatment of untreatable infection
Treatment of fever of unknown origin
Reliance on AB alone
Improper dosage
Lack of bacterial information
Treatment of Acute Prostatitis
Levofloxacin
Penicillin
Cephalosporins
Treatment of Chronic Prostatitis
Levofloxacin for 4-6 weeks
Treatment of Acute Pyelonephritis
IV Ampicillin, Amino-glycosides, Flouroquinolones for 2 weeks
