Surgical Wound Healing

Question 1

wound edges brought together

Answer 1

primary intention

Question 2

dermis without total penetration

Answer 2

primary

Question 3

with gauze, or drainage system

Answer 3

secondary

Question 4

granulation

Answer 4

secondary

Question 5

delayed closure

Answer 5

tertiary

Question 6

7 stages of skin healing

Answer 6

1. vascular/inflammatory
2. re-epithelization
3. granulation
4. fibroplasia, matrix formation
5. wound contraction
6. neovascularization
7. matrix, collagen remodeling

Question 7

epidermal cells from wound edge

Answer 7

re-epithelization

Question 8

granulation forms

Answer 8

3-5 days after wound formation

Question 9

fibronectin scaffold

Answer 9

fibroplasia and matrix formation

Question 10

differentiation of myofibroblasts

Answer 10

fibroplasia and matrix formation

Question 11

centripental movement of edges

Answer 11

wound contraction

Question 12

low o2 tension activates

Answer 12

macrophage derived angiogenic factor

Question 13

low o2 tension induces

Answer 13

neovascularization

Question 14

fragmentation of venule basement membrane

Answer 14

neovascularization

Question 15

pseudopodia

Answer 15

neovascularization

Question 16

type 3 collagen replaced by type 1

Answer 16

matrix and collagen remodeling

Question 17

protein deficiency

Answer 17

infection, inability to synthesize cells

Question 18

negative nitrogen balance

Answer 18

wound remodeling impaired

Question 19

vitamin k deficiency

Answer 19

hematoma

Question 20

anticoags

Answer 20

hematoma formation

Question 21

steroids

Answer 21

impairs wound healing

Question 22

macrophage derived angiogenic factor

Answer 22

neovascularization