Surgical Wound Healing Flashcards

1
Q

wound edges brought together

A

primary intention

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2
Q

dermis without total penetration

A

primary

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3
Q

with gauze, or drainage system

A

secondary

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4
Q

granulation

A

secondary

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5
Q

delayed closure

A

tertiary

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6
Q

7 stages of skin healing

A
  1. vascular/inflammatory
  2. re-epithelization
  3. granulation
  4. fibroplasia, matrix formation
  5. wound contraction
  6. neovascularization
  7. matrix, collagen remodeling
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7
Q

epidermal cells from wound edge

A

re-epithelization

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8
Q

granulation forms

A

3-5 days after wound formation

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9
Q

fibronectin scaffold

A

fibroplasia and matrix formation

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10
Q

differentiation of myofibroblasts

A

fibroplasia and matrix formation

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11
Q

centripental movement of edges

A

wound contraction

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12
Q

low o2 tension activates

A

macrophage derived angiogenic factor

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13
Q

low o2 tension induces

A

neovascularization

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14
Q

fragmentation of venule basement membrane

A

neovascularization

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15
Q

pseudopodia

A

neovascularization

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16
Q

type 3 collagen replaced by type 1

A

matrix and collagen remodeling

17
Q

protein deficiency

A

infection, inability to synthesize cells

18
Q

negative nitrogen balance

A

wound remodeling impaired

19
Q

vitamin k deficiency

A

hematoma

20
Q

anticoags

A

hematoma formation

21
Q

steroids

A

impairs wound healing

22
Q

macrophage derived angiogenic factor

A

neovascularization