Surgical Management of Lung Cancer Flashcards
What is considered in the assessment of the patient?
- Staging of the lung cancer
- Fitness of the patient
If the hilum of the lung lymph nodes are involved, what is this classed as?
N1
Where are the common sites of lung cancer metastasis?
- Brain
- Skeleton
- Other lung
- Adrenal glands
- Liver
How is lung cancer stages clinically?
- History
- Examination
What may be present in the history of someone with lung cancer?
- Pain (especially bony pain)
- Headaches
- Neurological symptoms including personality change
- Haematuria
What may be present on examination of someone with lung cancer?
- Recurrent laryngeal nerve palsy
- Brachial plexus palsy
- SVCO
- Supraclavicular LNs
- Soft tissue nodules
- Chest wall masses
- Pleural/pericardial effusion
- Hepatomegaly
What might be seen on the chest X-ray of someone with lung cancer?
- Pleural effusion
- Chest wall invasion
- Phrenic nerve palsy
- Collapsed lobe or lung
What might blood tests of someone with lung cancer show?
- Anaemia
- Abnormal LFTs
- Abnormal bone profile
What might be seen on the CT of someone with lung cancer?
- Size of tumour
- Mediastinal nodes
- Metastatic disease
- Proximity to mediastinal structures
- Pleural/pericardial effusion
- Diaphragmatic involvement
What other tests are useful in lung cancer staging?
- MRI
- Bone scan
- ECHO
What is an MRI useful for?
Useful in determining the degree of vascular and neurological involvement in Pancoast tumour
What is a bone scan useful for?
Good test for chest wall invasion and for bony metastases
What is an ECHO useful for?
Will demonstrate presence or absence of significant pericardial effusion
What surgical assessments can be carried out?
- Bronchoscopy
- Mediastinoscopy
What CV conditions need to considered when assessing fitness for surgery?
- Angina
- Heart problems
- HBP
- DM
- PVD
- Smoking
- Stroke/TIA
- Carotid bruits
- Previous CABG/angioplasty
- Heart murmurs
What respiratory conditions need to be considered when assessing fitness for surgery?
- Barrell-chested
- COAD
- Still smoking
- Asthmatic
- Recent URTI
- On oxygen
- Exercise capacity
- Previous thoracotomy or ICD
What psych conditions need to be considered when assessing fitness for surgery?
- PH of mental illness
- Severe anxiety
- Social background
- Chronic pain problems
What other conditions need to be considered when assessing fitness for surgery?
- Pulmonary hypertension
- Permanent tracheostomy
- Rheumatoid arthritis
- The immobile patient
- Cirrhosis
- h/o radiotherapy to chest
What respiratory function tests should be carried out during fitness for surgery assessment?
- Spirometry
- Diffusion studies
- ABG on air/SLV
- Fractioned V/Q scan
What cardiac tests should be carried out during fitness for surgery assessment?
- ECG
- ECHO
- CT scan
- ETT
- Coronary angiogram
- If in doubt, don’t operate
What are the principles of surgical treatment of lung cancer?
- Curative resection is the goal
- Remove the minimum amount of lung tissue
- Resection of parietal structures is feasible
- Firm diagnosis of malignancy is highly desirable before lung resection
What are the main reasons for peri-operative death?
- ARDS
- Bronchopneumonia
- Myocardial infarction
- PTE
- Pneumothorax
- Intrathoracic bleeding
What are the main non-fatal complications of lung cancer surgery?
- Post thoracotomy wound pain
- Empyema
- BPF
- Wound infection
- AF
- MI
- Post-op respiratory insufficiency
- Gasstroparesis/constipation
What are the commonest problems with staging of lung cancer?
- Collapse of a lobe or lung makes tumour size difficult to assess
- Presence of another (usually small) pulmonary nodule
- Retrosternal thyroid
- Adrenal nodule
- CT head is not routinely performed pre-op
What are the operative mortality stats?
- Pneumonectomy 8-12%
- Lobectomy 3-5%
- Wedge resection 2-3%
- Open/close thoracotomy 5%
What might it be if its not lung cancer?
- Infection: TB, lung abscess
- Benign tumour: Hamartoma
- Granuloma: Sarcoid, Wegner’s, Rheumatoid nodule, inflammatory pseudotumour
- Fibrosis- PMF, organising pulmonary infarct
- Other- Paraffinoma