Surgery Flashcards

1
Q

What should be assessed when looking at a patients airway in the ABCDE approach?

A

Look: Signs of obvious airway obstruction e.g. vomit, Chest wall excursion, See-saw breathing
Feel: Breath
Listen: Stridor, Gurgling

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2
Q

What can be done to treat if a patient is having a problem with their airway?

A

Head tilt and chin lift
Jaw thrust
Adjuncts: Guedel airway, Nasopharyngeal airway, Laryngeal mask airway
Definitive airway

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3
Q

What is the definition of a definitive airway?

A

Requires a tube present in trachea with cuff inflated, tube connected to some form of oxygen enriched assisted ventilation and airway secured with tape

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4
Q

What are the different types of definitive airway?

A
Endotracheal (ET) tube
Nasotracheal tube
Surgical airway (tracheostomy or cricothyroidotomy)
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5
Q

What can you look for to assess a patient’s breathing?

A
Central/peripheral cyanosis
Chest wall deformity
Abnormal chest expansion: Asymmetry, Flail, See-saw breathing
Tracheal tug
Accessory muscle usage
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6
Q

What can you feel for to assess a patient’s breathing?

A

Asymmetric chest expansion
Deviated trachea
Displaced apex beat
Percussion

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7
Q

What can you listen for to assess a patient’s breathing?

A

Auscultation: Absent breath sounds, Crackles, Wheeze

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8
Q

What can you measure to assess a patient’s breathing?

A

Respiratory rate
O2 saturations
ABG
CXR

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9
Q

What can you measure to assess a patient’s circulation?

A
Heart rate
Capillary refill
Blood pressure
Temperature
Urine output: 0.5 ml/kg/hr
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10
Q

What are the different types of shock?

A

Hypovolaemic
Cardiogenic
Distributive: anaphylactic, septic, neurogenic
Obstructive

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11
Q

What are signs of hypovolaemic shock?

A

Tachycardia
Tachypnoea
Cool peripheries
Altered mental state

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12
Q

Why should you not use BP as a measure of hypovolaemic shock?

A

BP is a reasonably late change so look for urine output/HR changes first. Can have lost 2L blood before any change

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13
Q

What is the difference between neurogenic and spinal shock?

A

Neurogenic: lose sympathetic tone
Spinal: temporary spinal paralysis

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14
Q

What is the SIRS criteria?

A
2 or more of the following:
HR: 90 or above 
RR: over 20 or PaCO2< 4.3kPa
Temp: below 36 or above 38
WCC: <4x109 cells/L OR >12x109 cells/L OR >10% immature neutrophils
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15
Q

What is lactic acid and what is it an effective measure of?

A

Formed when glucose is broken down, then oxidised to pyruvate
Reduces NADH to NAD+, which enables respiration to continue
When cells are in a hypoxic state, they are forced to metabolise glucose anaerobically. Leads to a build up of lactic acid
Good indicator of tissue perfusion/hypoxia

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16
Q

What is the enhanced recovery after surgery strategy?

A

Combination of evidence-based peri-operative strategies which work synergistically to expedite recover after surgery

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17
Q

What are pre operative recommendations for enhanced recovery after surgery?

A

Pre op counselling and training
Curtailed fast: 6h solids, 2h clear liquids, pre op carb loading
Avoidance of mechanical bowel prep
DVT prophylaxis using LMWH
Single dose of prophylactic abx covering aerobic and anaerobic pathogens

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18
Q

What are peri-operative recommendations for enhanced recovery after surgery?

A

High (80%) oxygen concentration in peri operative period
Prevention of hypothermia
Goal directed intra operative fluid therapy
Preferable use of short and transverse incisions for open surgery
Avoidance of post op drains and NG tubes
Short duration of epidural analgesia and local blocks

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19
Q

What are post operative recommendations for enhanced recovery after surgery?

A

Avoidance of opiates, use of paracetamol and NDSAIDs
Early commencement of post op diet
Early and structured post op mobilisation
Administration of restricted amounts of IV fluid
Regular audit

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20
Q

What factors are on the surgical safety checklist when patient signs in?

A

Patient confirms identity, site, procedure, consent
Site marked
Anaesthesia safety check completed
Pulse oximeter on patient and functioning
Allergies?
Airway/aspiration risk?
Risk of over 500ml blood loss? (7ml/kg in child)

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21
Q

What factors are on the surgical safety checklist before any skin incision?

A

Confirm all team members have introduced themselves by name and role
Surgeon, anaesthetist and nurse verbally confirm patient, site and procedure
Anticipated critical surgical events: operative duration, expected blood loss
Anticipated critical anaesthetic events: patient specific concerns
Anticipated critical nursing events: sterility confirmed, equipment issues
Abx prophylaxis been given in last 60 mins?
Is essential imaging displayed?

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22
Q

What factors are on the surgical safety checklist when patient signs out?

A

Nurse verbally confirms: procedure, instrument needle and sponge counts are correct, how specimens are labelled, whether there are any equipment problems to be addressed
Surgeon, anaesthetist and nurse review key concerns for recovery and management of this patient

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23
Q

What details should be included on a surgical consent form?

A

Procedure, side, location (joint)

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24
Q

How should limb marking for surgery be carried out?

A

Clear arrow
Indelible ink
Not at site of incision

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25
Q

What are benefits of minimally invasive surgery?

A

Increased safety: less blood loss, less trauma, less pain
Faster recovery
Decreased length of hospital stay
Decreased scarring

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26
Q

What are problems with minimally invasive surgery?

A
Depth of Field
Limited view
2-D vision
Paradoxical movement: fulcrum effect
Long, rigid instruments: Amplify tremor, fewer degrees of freedom
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27
Q

What different forms of robotic surgery are there?

A

Computer Assisted Surgery: surgeon generally holds tools and computers might help in planning and positioning
Robotic surgery: Robots will hold tools, providing greater accuracy
and precision
Telerobotics: area of robotics concerned with the control of robots from a distance

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28
Q

What are benefits of robotic surgery?

A
3D vision
Surgeon-controlled camera
Articulated working tips – 7 degrees of Freedom
Ergonomic
Tremor abolition
Motion Scaling
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29
Q

What are some problems with single incision laparoscopic surgery? And how can you overcome these?

A

Clutter of hands
Inadequate triangulation
Using instruments of different length
Using controllably flexible instruments

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30
Q

What is a NOTES procedure?

A

Natural Orifice transluminal endoscopic surgery

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31
Q

What are benefits of NOTES procedures?

A
No scars
No wound infection
Less pain
No hernias
No internal adhesions
Can perform surgery under sedation
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32
Q

What are advantages and disadvantages of surgical simulation?

A

Advantages: Safe, Flexible, Objective feedback
Disadvantages: cost, integration into curriculum, assessment validity

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33
Q

What post op complications are we aiming to minimise by improving surgical safety?

A

Pain
Confusion
Venous-thromboembolism
Surgical site infection

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34
Q

What is the most common post op complication?

A

Surgical site infection

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35
Q

What is the most common hospital acquired infection?

A

Surgical site infection

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36
Q

On average how many more days in hospital does a post op surgical site infection cause?

A

7

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37
Q

How much is death rate increased by a post op surgical site infection?

A

2-11 times

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38
Q

What strategies are used to prevent post op surgical site infection?

A
Antimicrobial prophylaxis, Discontinue as soon as possible
Do not remove hair
Control blood glucose
Maintain normothermia
Optimise oxygenation
Alcohol based skin prep
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39
Q

What is an acute abdomen?

A

Rapid onset of severe symptoms that may indicate potentially life-threatening intra-abdominal pathology that requires urgent surgical intervention

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40
Q

What questions are important when taking a Hx from a patient with an acute abdomen?

A
Pain: SQITAS
Vomiting
Bowels last open
Urinary symptoms
Bleeding
Weight loss
Anorexia
Fevers
Female: LMP, PV discharge, pregnant?
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41
Q

What aspects of the examination are important in a patient presenting with an acute abdomen?

A

Stable (Full examination) vs unstable (ABCDE)
End of bed inspection (jaundice, cachectic, lying still/writhing, vomit bowl, cigarettes)
Hands, face, lymph nodes, abdomen
Look, palpate, percuss, auscultate
Complete with hernial orifices and PR (with chaperone)

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42
Q

What can be inflammatory/infective causes of an acute abdomen?

A
Diverticulitis
Pyelonephritis
Appendicitis
Cholecystitis
Pancreatitis
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43
Q

What is a diverticulum?

A

Out-pouching of the colonic wall typically found on the sigmoid and descending colon

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44
Q

How will diverticulitis typically present?

A

Left iliac fossa pain

Fever

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45
Q

How might a perforated diverticulum which has formed a fistula present?

A

Recurrent UTI, PV brown discharge

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46
Q

How does appendicitis typically present? What sign might you look for?

A

Typically presents with migratory RIF pain
Tenderness and guarding in RIF
Anorexia
Rovsing’s sign: pressure in LIF increases pain in RIF due to bowel pushing onto inflamed appendix
Psoas sign: flexion of right leg causes irritation of peritoneum causing pain

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47
Q

What symptoms is a person with pyelonephritis likely to present with?

A

Flank pain
Urinary symptoms
Pyrexia

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48
Q

What investigation results would you get in a patient with pyelonephritis?

A

Raised WCC and CRP

Urine dip positive for leucocytes and nitrites

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49
Q

What is the management for a patient with pyelonephritis?

A

Treat with broad spectrum antibiotics and ensure renal function is not impaired. May require US KUB

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50
Q

What biliary problems could a patient have who is presenting with RUQ pain?

A

Biliary colic
Choledocholithiasis
Cholecystitis
Cholangitis

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51
Q

What is biliary colic?

A

Pain in the RUQ caused by gallstones

Stones become temporarily stuck in the cystic duct

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52
Q

What is choledocholithiasis?

A

Stone becomes stuck in the biliary tree

Causing pain without the presence of infection

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53
Q

How does Cholecystitis present?

A

Pain in the RUQ

Often present with fever

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54
Q

What would you see on USS of a patient with Cholecystitis?

A

Thick walled gallbladder

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55
Q

How is Cholecystitis managed?

A

Abx and IV fluids

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56
Q

What is charcots triad of ascending cholangitis?

A

Fever
Jaundice
Abdominal pain

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57
Q

What is the management for ascending cholangitis?

A

Abx, IVI and ERCP

Cholecystectomy when the condition has settled

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58
Q

What are some causes of bowel obstruction?

A

Intraluminal: foreign body, constipation, bezoar, gallstone
Intramural: Ca, stricture, volvulus, intersusseption
Extramural: Hernia, adhesions, Ca

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59
Q

If vomiting was the first symptom of a patient presenting with bowel obstruction, where is the obstruction likely to be?

A

Small bowel

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60
Q

How can you recognise a small bowel obstruction on an X-ray?

A

Centrally located multiple dilated loops of gas filled bowel
Valvulae conniventes - lines all the way across
Thin bowel wall

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61
Q

What vascular pathologies can present as an acute abdomen?

A

Mesenteric ischaemia
Ischaemic colitis
Ruptured AAA

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62
Q

What lactate result suggests vascular compromise in an acute abdomen setting?

A

Can be raised in biliary colic, but if greater than 7, likely to be vascular compromise

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63
Q

When looking for a perforation, what imaging modalities can be used? And what do you see?

A

Look for pneumoperitoneum on CXR
Lateral decubitus is more sensitive
CT is best

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64
Q

What are some medical causes of an acute abdomen?

A

Lower lobe pneumonia
Inferior MI
DKA
Porphyria

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65
Q

What investigations should be done for an acute abdomen?

A

Observations and simple bedside tests
Bloods: FBC, U and Es, CRP, Amylase, Clotting, G&S/X-match, VBG/ABG
Imaging: xray (erect chest, abdominal), USS, CT KUB and CT abdo/pelvis
Diagnostic laparoscopy

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66
Q

What are management steps for an acute abdomen?

A

ABCDE approach
IV access with bloods
Patient is likely to require fluid resuscitation not just maintenance fluids
Urinary catheter
Analgaesia according to WHO analgaesia ladder
Antiemetic
Obstruction or significant vomiting – NG tube
Abx
Consider NBM
SENIOR REVIEW

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67
Q

What is McBurney’s point?

A

1/3 distance from ASIS to umbilicus

Most common location of appendix

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68
Q

What would be your differentials for a 20 year old female with right iliac fossa pain?

A
Appendicitis
Ectopic pregnancy
Ruptured/torted ovarian cyst
Crohn's disease 
Meckels diverticulum
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69
Q

What is the most sensitive marker for pancreatitis?

A

Lipase

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70
Q

What are some causes of pancreatitis?

A
Gallstones
Ethanol
Trauma
Steroids
Mumps
Autoimmune
Scorpion sting
Hypercalcaemia/hyperlipidaemia
ERCP
Drugs (Azothiaprine, simvastatin)
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71
Q

What is the Glasgow score for pancreatitis severity?

A
Score of 3 or more - high risk of severe pancreatitis (death, surgery or complications)
PaO2 <8kPa
Age >55
Neutrophils – WCC >15
Calcium <2.0
Renal – Urea >16
Enzymes – AST/ALT >200 or LDH >600
Albumin <32
Sugar – Glucose >10
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72
Q

How do you manage pancreatitis?

A

IVI
UO monitoring
Analgaesia

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73
Q

What would be your differential list for a ruptured AAA?

A
Ruptured AAA
Inferior MI
Appendicitis 
Diverticulitis 
Pancreatitis 
Gallstones
Large bowel obstruction
Small bowel obstruction
Peptic ulcer disease
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74
Q

What is the management for a ruptured AAA?

A

Informing senior and vascular consultant early
Establishing 2 x large bore access in ACFs
Full set of bloods including xmatch for 4-6 units
Consider major haemorrhage protocol
Careful fluid resuscitation (target 90-100 sys BP)
Theatre

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75
Q

What are the gold standard best practice guidelines for patients with neck of femur fractures?

A

Time to surgery within 36h from arrival in ED or time of diagnosis to start of anaesthesia if an inpatient
Admitted under joint care of geriatrician and orthopaedic consultant
Admitted under assessment protocol agreed by geriatric medicine, orthopaedic surgery and anaesthetics
Assessed by geriatrician in post op period within 72 h of admission
Post op geriatrician directed MDT rehab team
Fracture prevention assessments - falls and bone health

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76
Q

What are the criteria for recommendation for liver transplant?

A

Arterial pH <7.3
Arterial lactate >3 after fluid rehydration
Within 24h: PT >100, creatinine >300, grade III/IV encephalopathy

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77
Q

What are extrahepatic/obstructive causes of jaundice?

A

Bile duct obstruction
Pancreatic cancer
Bile duct carcinoma
Gall stones

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78
Q

What are hepatic causes of jaundice?

A
Hepatitis 
EBV
Metastatic disease 
Primary hepatoma 
Alcoholic cirrhosis 
Primary biliary cirrhosis 
Autoimmune hepatitis
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79
Q

What are the causes of abdominal pain in nephrotic syndrome?

A

Peritonitis
Renal vein thrombosis
Hypovolaemia

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80
Q

What bugs can commonly cause septic arthritis?

A

Staphylococci
Streptococci
Gonococci - young sexually active
Pseudomonas - immunocompromised, IVDU

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81
Q

What is the clinical presentation of septic arthritis?

A

Pain
Pseudoparalysis
Pyrexia

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82
Q

Which joints are most commonly affected in septic arthritis?

A

Knee - 50%

Hip - 20%

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83
Q

What are your important differential diagnoses for septic arthritis?

A
Inflammatory arthritis
Crystal arthropathy
Reactive arthritis
Osteoarthritis
Trauma
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84
Q

What is Kochers criteria for septic arthritis?

A
Pyrexia >38.5 °C
Inability to weight bear
WCC >12.5
ESR >40
If 1 present, 1% chance 
If 2 present, 40% chance
If 3 present, 93% chance
If 4 present, 99% chance
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85
Q

What investigations would you do for septic arthritis?

A

Bloods (WBC, ESR, CRP, cultures)
Routine imaging (plain films, ultrasound)
Specialised imaging (CT, MRI, radionuclide)
Gold Standard is joint aspirate for microscopy and culture + tissue samples if possible
Do NOT give antibiotics unless patient in septic shock

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86
Q

What do you look for on a joint aspiration in septic arthritis?

A

Microscopy and Gram stain (only 60% positive)

WCC >50,000/microL, 75% polymorphonuclear leukocytes

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87
Q

What is the general management for septic arthritis?

A
Diagnosis (no antibiotics yet)
Surgery for debridement 
IV antibiotics
Oral antibiotics
Follow up
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88
Q

What surgery should be done in septic arthritis?

A

Arthroscopic or open washout of native joint infections
Prosthetic joint infections, artificial joint may be preserved in early infections but is usually revised in late infection

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89
Q

What role do antibiotics have in septic arthritis?

A

NOT until joint has been aspirated unless patient in septic shock
Initially broad spectrum to cover common organisms then adjust according to culture and sensitivities
IV until patient clinically and biochemically improving then prolonged course of oral antibiotics (4 to 6 weeks commonly recommended)
Consider dose and concentration in bone/joint
Consider poly antimicrobial therapy
Close liaison with medical microbiology
Multi-disciplinary care
Long-term antibiotic suppression in certain cases

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90
Q

What is compartment syndrome?

A

Increased pressure within a closed fascial compartment leading to impaired tissue perfusion

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91
Q

Which compartments are the most commonly affected in compartment syndrome?

A

Lower leg

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92
Q

What percent of tibial fractures are complicated by compartment syndrome?

A

Between 1% and 9%

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93
Q

How is the diagnosis of compartment syndrome made?

A

Clinical diagnosis
Pain most important initial symptom, exacerbated on passive stretch of the muscles that traverse the affected compartment
Paraesthesia, Pallor, Pulselessness and Paralysis are late features

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94
Q

How do you diagnose compartment syndrome in those who are comatose or who cannot communicate pain?

A

Confirmed by compartment pressure monitoring

Pressure of 30mmHg or within 20mmHg of diastolic BP

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95
Q

What is the management of compartment syndrome?

A

Release all casts, splints and dressings down to skin
Elevate limb
Analgesia
Keep NBM but don’t delay surgery for fasting
Emergency Fasciotomy (full, open release of all compartments in the limb segment affected)

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96
Q

What is an open fracture?

A

A broken bone that is in communication through the skin with the environment

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97
Q

What is the golden hour in polytrauma?

A

Highest likelihood that prompt medical treatment in this time will prevent death

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98
Q

What is the gustilo classification of open fractures?

A

I Low energy, wound less than 1 cm
II Wound greater than 1 cm with moderate soft tissue damage
III High energy wound greater than 1 cm with extensive soft tissue damage
IIIA Adequate soft tissue cover
IIIB Inadequate soft tissue cover
IIIC Associated with arterial injury

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99
Q

What is the management framework for severe open fractures?

A

Boast 4
IV abx ASAP, in 3 hours of injury: Co-amoxiclav (1.2g) or Cefuroxime (1.5g) 8 hourly continued until wound debridement. Clindamycin 600mg, 6 hourly if penicillin allergy
Vascular and neuro status of limb assessed, repeated at intervals, particularly after reduction of fractures or application of splints
Vascular impairment requires immediate surgery and restoration of circulation using shunts, ideally in 3-4 hours, with a max acceptable delay of 6 hours warm ischaemia
Compartment syndrome - immediate surgery, with 4 compartment decompression via 2 incisions
Urgent surgery in some multiply injured patients with open fractures or if wound is heavily contaminated by marine, agricultural or sewage matter
Combined plan for management of soft tissues and bone by plastics and orthopods
Wound handled only to remove gross contamination and to allow photography, then covered in saline-soaked gauze and an impermeable film to prevent desiccation
Limb, including knee and ankle, is splinted
Centres that cannot provide combined plastic and orthopaedic surgical care for severe open tibial fractures have protocols in place for early transfer of patient to an appropriate specialist centre
Primary surgical treatment (wound excision and fracture stabilisation) of severe open tibial fractures only takes place in non-specialist centre if patient cannot be transferred safely
Wound, soft tissue and bone excision (debridement) performed by senior plastic and orthopaedic surgeons working together on scheduled trauma operating lists within normal working hours and within 24 hours of injury unless there is marine, agricultural or sewage contamination. 6 hour rule does not apply for solitary open fractures. Co-amoxiclav (1.2g) and Gentamicin (1.5mg/kg) administered at wound excision, continued for 72 hours or definitive wound closure
If definitive skeletal and soft tissue reconstruction is not to be undertaken in single stage, vacuum foam dressing or antibiotic bead pouch applied until definitive surgery
Definitive skeletal stabilisation and wound cover are achieved within 72 hours and should not exceed 7 days

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100
Q

What is the difference between subluxation, dislocation and a fracture dislocation?

A

Subluxation – incomplete luxation or dislocation; although a
relationship is altered, contact between joint surfaces remains
Dislocation – abnormal separation in the joint, where two or more bones meet
Fracture dislocation - fracture of a bone near a joint, also involving
dislocation

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101
Q

What are potential problems with joint dislocation?

A
Joint damage
AVN
Soft tissue damage 
Pain
Neuro –vascular complications
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102
Q

Where do fracture blisters most commonly occur?

A

Ankle, wrist elbow and foot

Areas where skin adheres tightly to bone with little subcutaneous fat cushioning

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103
Q

What are two orthopaedic approaches to polytrauma patients?

A

Damage control orthopaedics: acute phase - life saving procedures, second phase - control haemorrhage, temp stabilisation of major fractures, manage soft tissue injuries, third phase - monitoring in ICU, fourth phase - definitive fracture fixation
Early total care: definitive fixation of all fractures in one trip to theatre

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104
Q

Why are hip fractures important?

A
Common
Vulnerable patients
High mortality
Financial burden
Social burden
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105
Q

Why do we try and operate early on hip fractures?

A

Pain relief

Allow early mobilisation and discharge

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106
Q

What is the alternative to surgery for a hip fracture and what problems does this cause?

A

Bed rest / traction: Pressure sores, Pneumonia, Thromboembolism, UTI, Death

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107
Q

What is the national hip fracture database best practice tariff criteria for hip fractures?

A

Admitted to orthopaedic ward within 4 hours
Operation within 36 hours from arrival to ED or time of diagnosis if inpatient to start of anaesthesia
Admitted under joint care of orthopaedic surgeon and geriatrician
Geriatrician perioperative assessment review within 72 hours
Mental state assessment - 2 AMT test scores, before and after surgery
Falls assessment
Osteoporosis treatment

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108
Q

Which 4Ms are important in the history of a patient with a suspected hip fracture?

A

Mechanism
Medical History
Mobility
AccoMModation

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109
Q

What examination findings/underlying problems will you particularly look for in a patient with a suspected hip fracture?

A

Respiratory: Pneumonia, COPD
Cardiovascular: Murmur, Dehydrated
Neuro: Stroke, AMTS
Musculoskeletal: NV intact, Open #

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110
Q

What bedside tests would you do for a patient with a suspected hip fracture?

A

ECG
Urine dip
BM

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111
Q

What bloods would you do for a patient with a suspected hip fracture?

A
FBC
U and Es
Clotting
Group and Save
Bone Profile
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112
Q

What imaging or special tests might you send a patient for who has a suspected hip fracture?

A

CXR
Echo
Skeletal x-rays

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113
Q

What interventions would you do for a patient with a suspected hip fracture?

A
IV fluids
Analgesia: Beware opioids but do not undertreat pain, Immobilisation, Nerve block
Laxatives
DVT prophylaxis
Antibiotics
Surgery
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114
Q

What landmark determines whether a hip fracture is intra or extracapsular?

A

Intertrochanteric line
Proximal to this is intracapsular: subcapital, transcervical, basicervical
Extracapsular: intertrochanteric and subtrochanteric

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115
Q

If an intracapsular neck of femur fracture is un-displaced, what is your management?

A

Fixation

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116
Q

What are pros and cons of fixation in intracapsular NOF fractures?

A

Pros: quick, non invasive, preserves own hip
Cons: 25% risk AVN, 15% risk non union

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117
Q

How does a patient’s age and function affect your management in a displaced intracapsular neck of femur fracture?

A

Young (<55): fixation
Old and poor function: Hemiarthoplasty
Old and good function: total hip replacement

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118
Q

What are differences between hemiarthroplasty and total hip replacements in terms of pros and cons?

A

Hemi: Smaller operation, Acetabular wear
THR: Bigger procedure, Dislocation

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119
Q

What is your management for an intertrochanteric hip fracture?

A

Dynamic hip screw

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120
Q

What is your management for a subtrochanteric hip fracture?

A

Intermedullary nail

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121
Q

What line will be disrupted in an intracapsular neck of femur fracture?

A

Shentons line

Inferior border of superior pubic ramus along inferomedial border of neck of femur

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122
Q

What childhood condition could be indicated by disruption of shentons line with no history of trauma?

A

Developmental dysplasia of the hip

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123
Q

What is the garden classification of hip fractures?

A

I: incomplete or impacted bone injury with valgus angulation of distal component
II: complete but undisplaced
III: partially displaced
IV: complete, totally displaced

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124
Q

At what diameter is the indication for surgery on an asymptomatic abdominal aortic aneurysm?

A

5.5cm and above

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125
Q

Which bone fracture can lead to fat embolism?

A

Long bone

Pelvic

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126
Q

What is the classic presentation of fat embolism?

A

Asymptomatic interval after long bone/pelvic fracture

24-48h later - pulmonary and neurological manifestations with petechial haemorrhages

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127
Q

Which analgesic produces prompt but short lasting analgesia, is less constipating than morphine but even at high doses is a less potent analgesic?

A

Pethidine

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128
Q

What are indications for pethidine use?

A

Moderate to severe pain
Obstetric analgesia
Peri operative analgesia

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129
Q

What local side effects may occur from a fentanyl patch?

A

Rash
Erythema
Itching

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130
Q

Which analgesic is a WHO class 3 analgesic which produces analgesia by an opioid effect but also an enhancement of serotonin and andrengeric pathways?

A

Tramadol

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131
Q

What are some side effects of Tramadol?

A
Nausea
Hypotension
Anaphylaxis
Hallucinations
Confusion
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132
Q

A 60 year old patient who has a history of exertional calf pain presents with acute abdominal pain which radiates through to his back. On examination his pulse is 110 BP 90/60. What is the immediate management?

A

IV access and fluids - urgent but limited, over treatment of ruptured AAA can cause more bleeding - keep BP around 100 systolic and save blood for operation
Stabilise his condition prior to confirmation of diagnosis/urgent laparotomy

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133
Q

A 74 year old man has undergone an elective open abdominal aortic aneurysm repair. On the sixth post operative day he has not opened his bowels or passed flatus. On examination, he has a distended abdomen with no audible bowel sounds. What is likely going on?

A

Postoperative ileus

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134
Q

What exacerbates postoperative ileus?

A

Excessive bowel handling

Prolonged procedures

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135
Q

A 71 year old woman has undergone an elective right hemicolectomy for a Dukes B caecal tumour. On the fifth post operative day she has developed abdominal pain and a low grade pyrexia. On examination she is tender on the right side of the abdomen. Her white cell count has risen to 20. What is the likely diagnosis?

A

Anastomotic leak

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136
Q

What are reasons for anastomotic leaks?

A

Technical reasons: poor operative technique, ischaemia

Systemic reasons: hypotension, anaemia

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137
Q

If a renal calculus is confirmed in a patient, levels of what things should be checked?

A

Uric acid
Calcium
PTH

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138
Q

How might you confirm a diagnosis of a renal calculus?

A

IV pyelogram

CT KUB

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139
Q

What are important things to check in a patient with pyelonephritis?

A

Renal function - U and Es

USS to examine for dilated draining system which would require urgent nephrostomy for decompression

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140
Q

What can be a complication of mastitis which may result in a swinging fever?

A

Breast abscess

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141
Q

What is the common infective organism in mastitis/breast abscess?

A

Staphylococcus aureus

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142
Q

A 46 year old woman presents to clinic experiencing a painful right nipple. The retroareolar area is erythematous and there is nipple retraction. You also notice a thick blood stained green nipple discharge. On palpation the woman feels tenderness originating from behind the nipple. There is no lymphadenopathy. What is the likely diagnosis?

A

Duct ectasia

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143
Q

What is duct ectasia?

A

Widening of the major ducts just behind the nipple

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144
Q

What is a major differential diagnosis for duct ectasia which has caused nipple retraction?

A

Carcinoma

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145
Q

What is a galactocoele?

A

Smooth fluctuant lump in a lactating woman

Lactiferous duct becomes plugged with thick milk protein

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146
Q

How does trauma to the breast lead to fat necrosis?

A

Haemorrhage
Cystic degeneration
Calcification of cysts leading to firm lump tethered to skin

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147
Q

What are differentials for a femoral hernia?

A

Cyst of canal of nuck
Ectopic testis
Psoas abscess
Saphena varix

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148
Q

A 24 year old man attends ED with a cold and painful right forearm. He is an IVDU. The pain has been getting worse for 24h. He has injection site marks around his brachial artery. On examination the hand is cold and paralysed with ischaemic areas at the tips of the digits. The radial and ulnar pulses are palpable. What is the first line in management? Why?

A

Heparinisation
It is likely that they have embolised the digital arteries with bulking agent mixed with his heroin
Too distal for embolectomy so heparinisation whilst ensuring adequate hydration to prevent myoglobinuria

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149
Q

What is the gold standard test for a DVT?

A

Venogram

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150
Q

How do you treat DVT?

A

Anticoagulation

Initially heparin followed by warfarin due to the potential risk of embolisation

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151
Q

In which patients are paraumbilical hernias most commonly seen?

A

Obese, multiparous middle aged women

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152
Q

Where is the weakness in a paraumbilical hernia?

A

Linea alba

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153
Q

Why do patients with paraumbilical hernias often have nausea?

A

Traction on the omentum entangled in the hernia sac

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154
Q

Why should paraumbilical hernias be repaired surgically?

A

Narrow neck so significant risk of irreducibility and strangulation

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155
Q

What are important diagnoses to consider in a patient with pain in the right iliac fossa?

A
Acute appendicitis
UTI
Right renal calculi 
Crohns ileitis
PID 
Ruptured ectopic pregnancy
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156
Q

A 76 year old man underwent emergency repair of an abdominal aortic aneurysm five days ago. He has made a good recovery and is mobilising well. He suddenly develops diarrhoea which contains moderate amounts of fresh blood. What is the most important next diagnostic investigation?

A

CT angiography - aorta

Look for fistula between stent and bowel

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157
Q

What are cardinal features of critical ischaemia?

A

Ulceration
Gangrene
Foot pain at rest

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158
Q

What is Leriches syndrome? What are the symptoms?

A
Aortoiliac occlusive disease 
Blockage of abdominal aorta as it transitions into common iliac arteries 
Claudication of buttocks and thighs
Absent or decreased femoral pulses 
Erectile dysfunction
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159
Q

What is Buergers disease? What is an important risk factor?

A

Thomboangitis obliterans
Segmental inflammation and thrombosis of small and medium sized arteries and veins of peripheral limbs
Heavy smoking risk factor
Presents as claudication in feet/hands at rest worse with cold/stress
Numbness, Raynauds, ulceration

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160
Q

What is the Fontaine classification for peripheral artery disease?

A

1: asymptomatic
2: intermittent claudication
3: ischaemic rest pain
4: ulceration/gangrene (critical ischaemia)

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161
Q

What are normal and abnormal results for ABPI?

A

Normal 1-1.2
Peripheral artery disease 0.5-0.9
Critical limb ischaemia <0.5

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162
Q

What imaging should you do for peripheral artery disease?

A

Colour duplex USS first line

MRA/CT angio if considering intervention

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163
Q

What are management options for peripheral artery disease?

A

Risk modification: quit smoking, treat HTN and hypercholesterolaemia, clopidogrel
Manage claudication: supervised exercise program to increase collateral blood flow, naftidrofuryl oxalate
Conservative fails/ severely affecting QOL/limb threatening: percutaneous transluminal angioplasty, surgical reconstruction
Amputation

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164
Q

In what time frame is surgery required to save the limb in acute limb ischaemia?

A

Emergency revascularisation surgery required in 4-6h

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165
Q

What may be some reasons for offering a woman a mastectomy rather than a wide local excision for treating breast cancer?

A

Multifocal tumour
Central tumour
Large lesion in small breast
DCIS >4cm

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166
Q

What are the criteria for offering post surgical radiotherapy to women with breast cancer?

A

Whole breast radiotherapy is recommended after a woman has had a wide-local excision to reduce recurrence risk by 2/3
After mastectomy radiotherapy offered for T3-T4 tumours and those with 4 or more positive axillary nodes

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167
Q

Which adjuvant hormone therapy is used in post menopausal women with breast cancer?

A

Aromatase inhibitors such as anastrozole

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168
Q

What are some important side effects of tamoxifen?

A

Increased risk of endometrial cancer, venous thromboembolism and menopausal symptoms

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169
Q

In which patients can Trastuzumab not be used? When is it used?

A

Cannot be used in those with Hx of heart disorders

Used to treat HER2 positive breast cancer

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170
Q

What should be done with regards to oestrogen containing contraceptive pills before elective surgery? What if this isn’t possible/hasn’t been done?

A

Preferably discontinued (adequate alternative arrangements made) 4 weeks before major elective surgery and all surgery to legs or surgery which involves prolonged immobilisation of a lower limb
Normally recommenced at first menses at least 2 weeks after full mobilisation
Progestogen-only contraceptive may be offered as an alternative and the oestrogen-containing contraceptive restarted after mobilisation, as above
If not possible, e.g. after trauma or patient admitted for elective procedure still on oestrogen-containing contraceptive, thromboprophylaxis (unfractionated or low molecular weight heparin and graduated compression hosiery) is advised

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171
Q

Which surgical patients are at increased risk of DVT?

A

Surgery greater than 90 minutes at any site
Greater than 60 minutes if procedure involves lower limbs/pelvis
Acute admissions with inflammatory process involving abdominal cavity
Expected significant reduction in mobility
Age over 60 years
Known malignancy
Thrombophilia
Previous thrombosis
BMI >30
Taking hormone replacement therapy or contraceptive pill
Varicose veins with phlebitis

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172
Q

What are options for mechanical thromboprophylaxis in surgical patients?

A

Early ambulation after surgery is cheap and is effective
Compression stockings (contra -indicated in peripheral arterial disease)
Intermittent pneumatic compression devices
Foot impulse devices

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173
Q

How can you reverse the effects of unfractioned heparin?

A

Protamine sulphate

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174
Q

What is Dabigatran?

A

Orally administered direct thrombin inhibitor

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175
Q

What are medical indications for circumcision?

A

Phimosis
Recurrent balanitis
Balanitis xerotica obliterans
Paraphimosis

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176
Q

What are benefits of circumcision?

A

Reduces risk of penile cancer
Reduces risk of UTI
Reduces risk of acquiring sexually transmitted infections including HIV

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177
Q

Which types of renal stones are radio-lucent and therefore might not show up on an X-ray?

A

Urate stones
Cystine stones- semi opaque
Xanthine stones

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178
Q

Which infections predispose to the formation of staghorn calculi?

A

Ureaplasma urealyticum and Proteus infections

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179
Q

What is a staghorn calculi?

A

In renal pelvis and extend into at least 2 calyces

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180
Q

The mother of a 2-month-old boy comes to surgery as she has noticed a soft lump in his right groin area. There is no antenatal or postnatal history of note. He is breast feeding well and is opening his bowels regularly. On examination you note a 1 cm swelling in the right inguinal region which is reducible and disappears on laying him flat. Scrotal examination is normal. What is the most appropriate action?

A

Refer to paediatric surgery for repair due to risk of incarceration

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181
Q

What is a spigelian hernia?

A

Lateral ventral hernia
Rare and seen in older patients
A hernia through the spigelian fascia (aponeurotic layer between rectus abdominis muscle medially and semilunar line laterally)

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182
Q

What is a richter hernia?

A

A rare type of hernia where only the antimesenteric border of the bowel herniates through the fascial defect

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183
Q

What are risk factors for abdominal wall hernias?

A

Obesity
Ascites
Increasing age
Surgical wounds

184
Q

What is a normal aortic size and what is considered aneusymal?

A

After age of 50 years normal diameter of infrarenal aorta is 1.5cm in females and 1.7cm in males
Diameters of 3cm and greater, are considered aneurysmal

185
Q

How does Paget’s disease of the nipple differ from eczema?

A

Paget’s involves the nipple primarily and only latterly spreads to the areolar, the opposite occurs in eczema

186
Q

What is Riglers sign (double wall sign)? And what does it show is present?

A

Presence of air on both sides of the intestine on an abdominal X-ray
Shows pneumoperitoneum suggesting perforation
However, a false double wall sign can result from two loops of bowel being in contact with one another

187
Q

Which medical patients are at risk of DVT?

A

Mobility significantly reduced for 3 or more days

If expected to have ongoing reduced mobility relative to normal state plus any VTE risk factor

188
Q

What are VTE risk factors?

A

Active cancer or cancer treatment
Age over 60
Critical care admission
Dehydration
Known thrombophilia
Obesity
One or more significant medical comorbidities
Personal Hx or first degree relative with history of VTE
Use of HRT
Use of oestrogen containing contraceptive
Varicose veins with phlebitis

189
Q

What are the general rules with VTE prophylaxis for medical and surgical patients?

A

Medical patients: pharmacological VTE prophylaxis unless contraindication
Surgical: mechanical offered for patients at risk. Pharmacological given if risk of major bleeding is low

190
Q

What are pharmacological VTE prophylaxis options?

A

Fondaparinux sodium
Low molecular weight heparin
Unfractionated heparin (for patients with renal failure)

191
Q

What are mechanical VTE prophylaxis options?

A

Anti embolic stockings
Foot impulse devices
Intermittent pneumatic compression devices

192
Q

What length of post procedure VTE prophylaxis is given for elective hip and knee replacement and hip fracture?

A

Elective hip: 28-35 days
Elective knee: 10-14 days
Hip fracture: 28-35 days

193
Q

What are the borders of the femoral canal?

A

Lateral: femoral vein
Medial: lacunar ligament
Anterior: inguinal ligament
Posterior: pectineal ligament

194
Q

What are the contents of the femoral canal?

A

Lymph vessels

Cloquets lymph node

195
Q

What is the physiological significance of the femoral canal?

A

Allows femoral vein to expand to allow for increased venous return to the lower limbs

196
Q

What is the triad of symptoms of Leriche syndrome?

A

Claudication of buttocks and thighs
Atrophy of musculature of legs
Impotence due to paralysis of L1 nerve

197
Q

A 72 year old man has just undergone surgery to repair a ruptured AAA. Pre op he was taking aspirin, clopidogrel and warfarin. Intra op he received 5000 units unfractioned heparin prior to application of aortic cross clamp. His blood results on admission to crit care show: Hb 8, platelets 40, WBC 7.1. His fibrin degradation products are markedly elevated. What is it?

A

Disseminated intravascular coagulation

198
Q

Describe the pathophysiology of DIC

A

Tissue factor release after vascular damage binds with coagulation factors and triggers the extrinsic pathway via factor VII which then also triggers the intrinsic pathway (XII to XI to IX)

199
Q

How many days before surgery should clopidogrel be stopped?

A

Elective procedures when antiplatelet effect is not needed, discontinue 7 days before surgery

200
Q

A 19 year old female presents with severe anal pain and bleeding which occurs post defecation. On examination she has a large posteriorly sited fissure in ano. What is the appropriate management?

A
Stool softeners
Topical diltiazem or GTN for 6 weeks 
Botox
Sphincterotomy 
Advancement flap
201
Q

A 43 year old male has been troubled with symptoms of post defecation bleeding for many years. On examination he has large prolapsed haemorrhoids, colonoscopy shows no other disease. What is the appropriate management?

A

Stool softeners
Avoid straining
If haemorrhoid complex is largely internal: stapled haemorroidopexy
Large external component: Milligan Morgan stole conventional haemorroidectomy

202
Q

What are adverse effects of a stapled haemorroidopexy?

A

Urgency

Recurrence

203
Q

What is a potential adverse effect of Milligan Morgan style haemorroidectomy?

A

Anal stenosis

Post op pain

204
Q

What are potential problems with a sphincterotomy to treat fissure in ano?

A

Incontinence to flatus

In females - pregnancy - faecal incontinence

205
Q

What is the management for a fistula in ano?

A

If low, no sphincter involvement or IBD: lay open (fistulotomy)
If complex, high or IBD, assess with surgery and imaging, insert draining seton suture, if not IBD - advancement flap, LIFT procedure

206
Q

What is the ginkgo leaf sign?

A

Chest plain radiography appearance which is seen with subcutaneous emphysema of the chest wall
Air outlines the fibres of the pectoralis major muscle and creates a branching pattern like a ginkgo leaf

207
Q

What are some potential complications of laparoscopic surgery?

A

General risks of anaesthetic
Vasovagal reaction in response to abdominal distension
Extra peritoneal gas insufflation: surgical emphysema
Injury to GI tract
Injury to blood vessels: common iliacs, deep inferior epigastric

208
Q

What are exclusion criteria for consideration of renal transplant?

A
Active malignancy
Old age
Infection
Severe coronary artery disease 
Severe pulmonary disease FEV1 less than 1.25L/min
Patient refusal
209
Q

What type of incision is used for kidney transplant?

A

Rutherford Morrison incision

210
Q

What is a common problem encountered in cadaveric kidneys which are used in organ transplant?

A

Acute tubular necrosis

211
Q

How long do kidney transplants tend to last?

A

Cadaveric donors - 9 years

Monozygotic twin live donor - 25 years

212
Q

What are some associations of sigmoid volvulus?

A
Older patients
Chronic constipation
Chagas' disease
Parkinson's disease
Duchenne muscular dystrophy
Schizophrenia
213
Q

What are some associations of caecal volvulus?

A

All ages
Adhesions
Pregnancy

214
Q

What are features of a volvulus?

A

Constipation
Abdominal bloating
Abdominal pain
Nausea and vomiting

215
Q

What is the management for sigmoid volvulus?

A

Rigid sigmoidoscopy with rectal tube insertion

216
Q

What is the management of caecal volvulus?

A

Often require right hemicolectomy

217
Q

What measures may increase the risk of surgical site infection?

A

Shaving the wound using a razor
Using non iodine impregnated incise drape
Tissue hypoxia
Delayed administration of prophylactic antibiotics in tourniquet surgery

218
Q

Give some examples of surgeries where use of prophylactic antibiotics is not recommended

A
Tonsillectomy
Inguinal hernia repair
Laparoscopic removal of ectopic pregnancy
Assisted delivery (forceps)
Evacuation of incomplete miscarriage
219
Q

What should be done for a low rectal cancer that is presenting with obstruction? Why?

A

Defunction with loop colostomy
Obstructed colon that would be used for anastamosis would carry high risk of dehiscence
Emergency presentation, staging may not be completed and so an attempted resection may compromise the circumferential resection margin with risk of local recurrence

220
Q

What are complications of diverticulitis?

A

Abscess formation
Peritonitis
Obstruction
Perforation

221
Q

What is the appropriate VTE prophylaxis for a patient undergoing an elective hip replacement?

A

TED stockings and dalteparin sodium started at least 6 hours post op

222
Q

What is the gold standard investigation for suspected urolithiasis?

A

CT KUB

223
Q

What is the management for biliary colic?

A

If imaging shows gallstones then laparoscopic cholecystectomy

224
Q

What is the management for acute Cholecystitis?

A

USS and cholecystectomy ideally within 48 hours of presentation

225
Q

What is Mirizzi syndrome?

A

Gallstone becomes impacted in the cystic duct or neck of gallbladder causing compression of the common bile duct or common hepatic resulting in obstruction and jaundice

226
Q

What is Calots triangle? Why is it relevant?

A

Hepatobiliary triangle - anatomic space bordered by cystic duct inferiorly, common hepatic duct medially and the inferior surface of the liver superiorly
Cystic artery lies in this space which is useful to identify for a lap chole

227
Q

What is the lymph node called that is located in calots triangle?

A

Mascagnis lymph node

228
Q

What is the management for a gallbladder abscess?

A

Imaging with USS +/- CT scan
Ideally surgery although subtotal cholecystectomy may be needed if calots triangle is hostile
If unfit patient, percutaneous drainage

229
Q

What is the management for cholangitis?

A

Fluid resuscitation
Broad spec IV Abx
Correct coagulopathy
Early ERCP

230
Q

How does gallstone ileus present?

A

History of previous Cholecystitis and known gallstones

Small bowel obstruction, may be intermittent

231
Q

What is the management for gallstone ileus?

A

Laparotomy and removal of gallstone from small bowel
Enterotomy made proximal to the site of obstruction
Fistula between gallbladder and duodenum should not be interfered with

232
Q

What is the management for acalulous Cholecystitis?

A

If patient is fit, cholecystectomy

If unfit, percutanenous cholecystostomy

233
Q

What are risks of ERCP?

A

Pancreatitis
Cholangitis
Duodenal perforation
Bleeding

234
Q

A 65 year old male attends surgical outpatients with epigastric discomfort. He has been recently diagnosed with diabetes and is a heavy smoker. An OGD is normal. What is a possible diagnosis? What is a rarer alternative that may present with a bullous rash?

A

Pancreatic Adenocarcinoma

Glucagonoma

235
Q

An obese 40 year old presents with episodes of anxiety, confusion and one convulsive episode. CT brain is normal. Abdominal CT shows a small lesion in the head of the pancreas. What is the likely diagnosis?

A

Insulinoma - episodes due to hypos

236
Q

What are some associations of pancreatic cancer?

A
Increasing age 
Smoking
Diabetes
Chronic pancreatitis 
Hereditary non polyposis colorectal carcinoma
Multiple endocrine neoplasia
BRCA2
237
Q

What are features of pancreatic cancer?

A

Painless jaundice
Anorexia
Weight loss
Epigastric pain
Loss of exocrine function - steatorrhoea
Back pain
Migratory thrombophlebitis - Trousseau sign

238
Q

What is the management of pancreatic cancer?

A

Whipples resection - pancreaticoduodenectomy
Adjuvant chemotherapy
ERCP with stenting for palliation

239
Q

What are the stages of wound healing? Describe each

A

Haemostasis: Minutes to hours following injury. Vasospasm in adjacent vessels, platelet plug formation and generation of fibrin rich clot
Inflammation: days 1-5. Neutrophils migrate into wound (impaired in diabetes). Growth factors released. Fibroblasts replicate in adjacent matrix and migrate into wound. Macrophages and fibroblasts couple matrix regeneration and clot substitution
Regeneration: days 7 to 56. Platelet derived growth factor and transformation growth factors stimulate fibroblasts and epithelial cells.
Fibroblasts produce collagen network. Angiogenesis occurs and wound resembles granulation tissue
Remodeling: From 6 weeks to 1 year. Longest phase of healing. Fibroblasts become differentiated (myofibroblasts) and these facilitate wound contraction. Collagen fibres are remodeled. Microvessels regress leaving a pale scar

240
Q

Give examples of drugs which impair wound healing

A

Non steroidal anti inflammatory drugs
Steroids
Immunosupressive agents
Anti neoplastic drugs

241
Q

A 56-year-old man presents with episodic facial pain and discomfort whilst eating. He has suffered from halitosis recently and he frequently complains of a dry mouth. He has a smooth swelling underneath his right mandible. What is the most likely underlying diagnosis?

A

Stone impacted in Whartons duct - sialolithiasis

242
Q

After a complicated revision of a total hip replacement, an 80-year-old lady receives two units of packed red cells. Which drug should be prescribed between the units?

A

Furosemide - prevent fluid overload

243
Q

When are packed red cells used for transfusion?

A

Used for transfusion in chronic anaemia and cases where infusion of large volumes of fluid may result in cardiovascular compromise

244
Q

When is platelet rich plasma used for transfusion?

A

Usually administered to patients who are thrombocytopaenic and are bleeding or require surgery

245
Q

What does fresh frozen plasma contain?

A

Clotting factors, albumin and immunoglobulins

246
Q

When is fresh frozen plasma used?

A

Usually used in correcting clotting deficiencies in patients with hepatic synthetic failure who are due to undergo surgery

247
Q

What is the usual dose of fresh frozen plasma?

A

Usual dose is 12-15ml/Kg

248
Q

What is cryoprecipitate?

A

Formed from supernatant of FFP
Rich source of Factor VIII and fibrinogen
Allows large concentration of factor VIII to be administered in small volume

249
Q

What is SAG mannitol blood?

A
Removal of all plasma from a blood unit and substitution with:
Sodium chloride
Adenine
Anhydrous glucose
Mannitol
250
Q

What steps should be taken if a patient on warfarin needs immediate or emergency surgery?

A

Stop warfarin
Vitamin K: IV 4-6h to work, oral 24h
Fresh frozen plasma: 30ml/kg. Only if human prothrombin complex not available
Human prothrombin complex: bereplex. Reversal in 1h

251
Q

What is the sign in checklist before induction of anaesthesia?

A

Patient has confirmed: Site, identity, procedure, consent
Site is marked
Anaesthesia safety check completed
Pulse oximeter is on patient and functioning
Does the patient have a known allergy?
Is there a difficult airway/aspiration risk?
Is there a risk of > 500ml blood loss (7ml/kg in children)?

252
Q

What is psoas sign/cope test?

A

Patient lies on their left side and clinician extends the right hip with the knee fully extended. Abdominal pain on this movement indicates irritation of iliopsoas and possible appendicitis. This test usually indicates an appendix that lies in the retrocaecal position

253
Q

Up to what size of breast tumour can be removed by wide local excision?

A

4cm

254
Q

What are some causes of early (day 0-5) post op pyrexia?

A
Blood transfusion
Cellulitis
Urinary tract infection
Physiological systemic inflammatory reaction (usually within a day following the operation)
Pulmonary atelectasis
255
Q

What are some late (day 6 plus) causes of post op pyrexia?

A

Venous thromboembolism
Pneumonia
Wound infection
Anastomotic leak

256
Q

What are risk factors for the development of aneurysms?

A

Smoking
HTN
Syphilis
Connective tissue disease: ehlers danlos type 1, marfans syndrome

257
Q

What size of aortic dilation would be considered aneurysmal?

A

3cm and greater

258
Q

What is the standard of care for people with symptomatic gallstones?

A

Elective cholecystectomy

259
Q

Which cholecystectomy procedure is associated with more biliary injuries?

A

Laparoscopic

260
Q

What are benefits to a lap chole rather than open?

A
Reduced pain
Reduced wound complications
Reduced pulmonary complications
Shorted hospital stay
Earlier return to work
261
Q

What are common causes of nipple discharge?

A

Mammary duct ectasia
Duct papilloma
Galactorrhoea

262
Q

What is a phyllodes tumour?

A

Rare variant of fibroadenoma found in older women

263
Q

What are clinical features of fat necrosis of the breast?

A
Hard painful lump 
Irregular 
Tethering 
Bruising 
Spontaneously resolves
264
Q

How do you treat intraductal papilloma?

A

Surgical excision of affected segment - microdochectomy

265
Q

In a Chinese patient with jaundice, what might cause irregular filling defects in the biliary tree on USS?

A

Clonorchis sinensis infection
Hepatolithiasis
Choledocolithiasis

266
Q

What may be causes of iatrogenic stricture formation after cholecystectomy?

A

Early: inadvertent clipping of the common duct
Late: burn injury

267
Q

What is the management if a gallbladder polyp is identified?

A

Cholecystectomy as there is a risk of growth and transformation into a carcinoma
If polyp is large or has suspicious features, perform pre op CT as extended resection of gallbladder +/- liver may be required

268
Q

How does an empyema form in the gallbladder?

A

Stone lodges in cystic duct orifice
Mucous continues to be produced forming a mucocoele
Stagnant mucous then becomes secondarily infected leading to an abscess

269
Q

Why is pancreatitis pain relieved by sitting forward?

A

Allows stomach and small bowel to fall away from the pancreas in the retroperitoneum

270
Q

Who is more likely to get lobular carcinoma in situ?

A

Younger women

White

271
Q

A 56 yeard old man attends clinic for investigation of chronic epigastric pain, anorexia and weight loss. He also describes pale, loose, floating stool. What is the appropriate investigation at this point? What can be done to help?

A

Faecal elastase - chronic pancreatitis

Steatorrhoea indicates exocrine insufficiency - can be prescribed enzyme supplementation

272
Q

If a diagnosis of pancreatic cancer is suspected, what imaging should be done? What are you looking for?

A

CT - identify primary tumour, examine for liver mets and large volume peritoneal disease

273
Q

What blood tests are required to determine the severity of pancreatitis?

A
LDH
WBC
Glucose
Urea
Calcium
ABG - pA02
274
Q

A 65 year old woman has been diagnosed with a 3cm pancreatic carcinoma on CT following investigation of obstructive jaundice. There is some question of nodularity within the omentum of the upper abdomen. What should be done next?

A

Laparoscopy - need to ensure resectability in advance of laparotomy
If the question is of vascular invasion - endoscopic USS indicated

275
Q

If a patient is suspected of having cholangitis secondary to gallstones, what should be done next?

A

ERCP to confirm diagnosis and allow insertion of stent or sphincterotomy to drain infected bile

276
Q

What is the main early feature of compartment syndrome and how can you test for it?

A

Excessive pain made worse by passive stretch of the suspected group of muscles

277
Q

When should fasciotomy be undertaken for compartment syndrome?

A

Difference between diastolic and measured compartment pressure is less than 30 mmHg

278
Q

What are potential complications of compartment syndrome?

A
Necrosis of tissue
Volkmanns ishcaemic contracture
Nerve damage
Muscle damage
Rhabdomyolysis
Renal failure
279
Q

What is a Volkmanns ischaemic contracture?

A

Permanent flexion contracture of hand at the wrist, resulting in a claw-like deformity of the hand and fingers. Passive extension of fingers is restricted and painful. It is excruciatingly painful and disabling

280
Q

Who is at risk of developing paraumbilical hernias?

A

Obese, multiparous, middle aged women due to weakness of linea alba

281
Q

A 54 year old man is seen in clinic with a history of chronic right sided abdominal pain which is localised to the abdominal wall. On examination there is a small irreducible mass lateral to the rectus muscle at the level of the anterior superior iliac spines. What is the diagnosis?

A

Spigelian hernia - weakness in Spigelian fascia, which is aponeurotic layer between rectus abdominis muscle medially, and the semilunar line laterally

282
Q

What is a volvulus?

A

Rotation of an organ around its mesentery

283
Q

What is the most common site for volvulus formation? What are some other possible sites?

A

Sigmoid (75%)
Caecum
Transverse colon
Splenic flexure

284
Q

What will an ABG of a patient with mesenteric ischaemia show?

A

Metabolic acidosis

Raised lactate

285
Q

What is the definition of critical ischaemia?

A

One or more of:
Persistent rest pain for minimum of 2 weeks
Ulceration
Gangrene in conjunction with ankle systolic BP less than 50 mmHg

286
Q

What is the management of critical ischaemia?

A

Pain control
Imaging to see if candidate for reconstruction
If not, amputation may be appropriate

287
Q

What is the prevalence of AAA?

A

7.5% in men over 65

288
Q

What are risk factors for AAA?

A

Male
HTN
Hypercholesterolaemia
Smoking

289
Q

When should patients be offered a repair for a AAA?

A

5.5cm

290
Q

What are common sources of emboli in context of acute vascular ischaemia?

A

AF
Mural thrombus
Aorta
Peripheral aneurysms

291
Q

What is done to manage a femoral embolus?

A

Emergency embolectomy

292
Q

What are common sites of valvular incompetence causing varicose veins?

A

Saphenofemoral junction
Saphenopopliteal junction
Perforator veins

293
Q

What are predisposing factors for varicose vein formation?

A

Raised pelvic pressure: pregnancy, obesity, gynaecological malignancies
Prolonged standing: occupational

294
Q

What are indications for surgery for varicose veins?

A
Cosmesis
Pain
Ulceration
Bleeding
Eczema
Thrombophlebitis
295
Q

How are varicose veins treated?

A

Ligation at level of incompetent vein +/- stripping of vein segment

296
Q

What is a hamartoma?

A

Abnormal growth that consists of the same tissue from which it is derived

297
Q

What is it called when hamartomas occur in multiple sites throughout the body?

A

Cowden disease

298
Q

Where do papillomas develop in the breast?

A

Lactiferous ducts just below the nipple

299
Q

What is mammary duct ectasia?

A

Benign breast condition
Milk ducts beneath nipple become dilated and sometimes inflamed
Presents with chronic inflammation of breast, creamy protein rich green discharge

300
Q

What is a procedure specific risk which should be included on the consent form for low anterior resection and classically occurs at 5-7 days?

A

Anastamotic leak

301
Q

How is an low anterior resection anastamotic leak managed if there is evidence of sepsis?

A

Urgent laparotomy

Repair or defunctioning by means of ileostomy

302
Q

What should be done for cases of prolonged ileus?

A

Identify and correct any electrolyte abnormalities

Search for intra or extra abdominal infection

303
Q

When is atelectasis most commonly seen after surgery?

A

Prolonged operations
Upper abdominal surgery
Elevated intra abdominal pressure
Smokers

304
Q

How can you prevent the development of atelectasis?

A

Adequate analgesia
Optimal oxygenation
Physiotherapy

305
Q

In post op bleeding, what is the difference between reactionary and secondary haemorrhage?

A

During the first 48 hours (reactionary haemorrhage) because a clot in a vessel has been displaced, or a ligature has slipped
8 to 14 days later (secondary haemorrhage) when the wound has become infected and eroded a vessel, usually quite a small one, sometimes a larger one

306
Q

What causes a pilonidal sinus?

A

Ingrowing hairs

307
Q

How can people be treated who are prone to pilonidal sinuses?

A

Waxing the affected region

308
Q

A 52 year old man presents with a 3 week hx of increasing discomfort in the perianal region (he finds it extremely uncomfortable to sit down). He also complains of throbbing and swelling. What is the likely diagosis?

A

Perianal abscess

309
Q

A 45 year old woman presents with tenderness in the perianal region and says she can feel a lump. On examination there is a small pea sized lump, bluish in colour which is painful. There is no hx of weight loss. What is the likely diagnosis?

A

Perianal haematoma

310
Q

What are classic symptoms of rectal carcinoma?

A

Fresh blood
Mucus
Tenesmus
Diarrhoea

311
Q

Why does leg pain occur in intermittent claudication?

A

Blood flow to muscles is reduced, possibly due to atherosclerosis
Oxygen demand cannot be met and therefore anaerobic metabolism occurs and leads to an accumulation of lactic acid
This is painful and causes cramping

312
Q

What are risk factors for developing claudication?

A

Smoking
High total blood cholesterol or high LDL and low HDL
HTN
Obesity
Diabetes
FH of atherosclerosis, PAD or claudication

313
Q

What are features of mild to moderate intermittent claudication?

A

Ceases with rest
Elicited by reproducible amount of exercise
No worse at night compared to day time
May be an indication for bypass surgery

314
Q

What percent stenosis of the carotids requires operative intervention with a carotid endarterectomy?

A

Greater than 70%

315
Q

A 22 year old man presents to ED following an accident at work. A piece of scaffolding fell onto his leg and trapped it. His peripheral pulses are present on arrival. He is admitted for observation when he becomes hypotensive with a poor urine output. What is the diagnosis?

A

Rhabdomyolysis leading to AKI

316
Q

What procedure is used to treat a perforation?

A

Omental patch

317
Q

What procedure is used to treat and active bleeding duodenal ulcer which fails to respond to adrenaline injection?

A

Laparotomy with under running of the ulcer

318
Q

What should be done to treat a patient with a pyloric stenosis secondary to longstanding duodenal ulcers?

A

Gastroenterostomy

319
Q

An otherwise fit 80 year old lady presents with an 8 hour hx of acutely ischaemic right arm with severe pain in the hand and fingers. She has a hx of AF for which she takes digoxin. On examination the hand is cold and pale but some movement and sensation are preserved. There is a good axillary artery pulse but distal pulses are impalpable. What is the correct management?

A

Surgical exploration and embolectomy using a Fogarty catheter

320
Q

What is the inheritance pattern of osler Weber rendu syndrome? What is the other name for it?

A

Hereditary haemorrhagic telangiectasia

Autosomal dominant

321
Q

What is the triad of features of hereditary haemorrhagic telangiectasia?

A

Telangiectasia
Recurrent epistaxis
Positive family history for the disorder

322
Q

What is the most common finding on screening mammography?

A

Ductal carcinoma in situ - microcalcification

323
Q

What proportion of DCIS will progress to invasive cancer?

A

25%

324
Q

What is Paget’s disease of the nipple?

A

Invasion of the nipple by malignant cells from an underlying neoplasm

325
Q

How is a lactational breast abscess treated?

A

USS guided aspiration and antibiotic therapy

If it recurs then formal incision and drainage is required

326
Q

What is the condition where lipomas are multiple and familial?

A

Dercums disease

327
Q

What is the most common soft tissue sarcoma in children?

A

Rhabdomyosarcoma

328
Q

How can the risk of painful neuromas developing after amputation be reduced?

A

Cutting (not tying) nerves as short as possible and keeping the ends away from scar tissue

329
Q

What is a Desmoid tumour?

A

Highly vascularised fibrous tissue
Not malignant
Found in abdominal wall
Can be associated with FAP

330
Q

What are some reasons for post op ankle swelling?

A

Poor mobility
Low albumin and protein levels
DVT

331
Q

Why does anastamotic dehiscence occur?

A

Poor knotting
Poor suturing
Too much tension
Diabetic patients - ischaemia

332
Q

If traubs space is dull to percussion, what does that suggest?

A

Splenomegaly not yet large enough to be palpated abdominally

333
Q

What might a new onset umbilical hernia in an adult indicate?

A

Malignancy
Ascites
Multiple pregnancy
Peritoneal dialysis

334
Q

Where is the defect with an epigastric hernia?

A

Linea alba

335
Q

What are predisposing factors for incisional hernias?

A
Malnutrition - protein, vitamin C, zinc
Jaundice
Uraemia
COPD
Smoking
Obesity
Steroids
Post op: distension, wound infection, haematoma 
Poor technique: suture type, suture placement
336
Q

What factors increase the risk of cholelithiasis?

A

Haemolysis
Pregnancy
Oral contraceptive therapy
Octreotide therapy

337
Q

Which bugs are patients at risk of post splenectomy?

A

Pneumococcus
Haemophilus
Meningococcus
Capnocytophaga canimorsus

338
Q

Which vaccines should patients have if they have had a splenectomy?

A
2 weeks prior to surgery if elective
Hib
Meningitis A and C
Annual influezna vaccine
Pneumococcal every 5 years
339
Q

What antibiotic prophylaxis is recommended for post splenectomy patients?

A

Pen V
For at least 2 years and at least until patient is 16 years old
Majority are put on for life

340
Q

Why does pen V not protect post splenectomy patients from haemophilus infection?

A

Production of beta lactamases by the organism

341
Q

What are risks with carotid endarterectomy procedures?

A
Hypoglossal nerve neuropraxia/damage 
Perioperative stroke 
Haematoma 
MI 
Infection
Restenosis
342
Q

What is the management for uncomplicated sigmoid volvulus?

A

Endoscopy and decompression to relieve large bowel obstruction and prevent ischaemia

343
Q

What is the significance of a patient having colicky abdominal pain rather than continuous in the context of bowel obstruction?

A

Colicky pain suggests uncomplicated obstruction

Continuous pain suggests peritonitis - ischaemia or perforation

344
Q

For venous thromboembolism, how long should warfarin treatment be continued?

A

Provoked: 3 months
Unprovoked: 6 months

345
Q

Who should be screened for MRSA?

A

All patients awaiting elective admissions

All emergency admissions

346
Q

How should a patient be screened for MRSA?

A

Nasal swab and skin lesions or wounds
Swab wiped around rim of patients nose for 5 seconds
Microbiology form labelled MRSA screen

347
Q

What is a trendelenburg test for varicose veins?

A

Patient supine, leg flexed at hip and raised above heart
Veins will empty due to gravity or with assistance of examiner’s hand squeezing
Tourniquet around upper thigh to compress superficial veins but not too tight as to occlude deeper veins. Leg is then lowered by asking the patient to stand
Normally superficial saphenous vein will fill from below within 30–35 seconds as blood from capillary beds reaches veins
If superficial veins fill rapidly with tourniquet in place there is valvular incompetence below level of the tourniquet in deep or communicating veins.
After 20 seconds, if there has been no rapid filling, tourniquet is released. If there is sudden filling at this point, it indicates that the deep and communicating veins are competent but the superficial veins are incompetent

348
Q

How is MRSA suppressed if a patient is found to be a carrier?

A

Nose: mupirocin 2% in white soft paraffin, TDS for 5 days
Skin: chlorhexidine gluconate OD for 5 days particularly axilla, groin and perineum

349
Q

Which antibiotics are commonly used in the treatment of MRSA infections?

A

Vancomycin
Teicoplanin
Linezolid

350
Q

Which organisms are patients who have had a splenectomy at risk from?

A

Pneumococcus
Haemophilus
Meningococcus
Capnocytophaga canimorsus

351
Q

Which vaccinations should patients undergoing splenectomy have?

A

2 weeks prior: Hib, Meningitis A and C
Annual influenza
Pneumococcal vaccine every 5 years

352
Q

What are some causes of pseudo obstruction?

A
Hypothyroidism
Hypokalaemia
Diabetes 
Uraemia
Hypocalcaemia
353
Q

What is the Amsterdam criteria for aiding diagnosis of HNPCC?

A

At least 3 family members with colon cancer
Cases span at least 2 generations
At least one diagnosed before age 50

354
Q

What investigation needs to be done in a patient with an abdominal wall haematoma?

A

USS abdomen

Coagulation studies

355
Q

What is the Hinchey classification of diverticular perforations?

A

Hinchey I: localised abscess (para colic)
Hinchey II: pelvic abscess
Hinchey III: purulent peritonitis
Hinchey IV: faeculent peritonitis

356
Q

What is the management for diverticulitis?

A

Increase dietary fibre
Mild attacks: conservatively with antibiotics
Pericolic abscess: drainage
Recurrent episodes requiring hospitalisation: possible segmental resection
Hinchey IV perf: resection and usually stoma, HDU admission

357
Q

What is the management of fissure in ano?

A

GTN ointment 0.2% or diltiazem cream topically
Botox for those who fail to respond
Internal sphincterotomy for those who fail with Botox

358
Q

What is the management of haemorrhoids?

A

Lifestyle advice
If small internal: injection sclerotherapy or rubber band ligation
For external: haemorrhoidectomy - HALO or stapled

359
Q

What is leriches syndrome?

A

Aortoiliac occlusive disease
Blockage of abdominal aorta as it transitions into common iliacs
Presents with claudication of buttocks and thighs, absent or decreased femoral pulses and erectile dysfunction

360
Q

What is Mondors disease?

A

Thrombophlebitis of superficial veins of breast causing tender subcutaneous cords
Self limiting
Treated with NSAIDs

361
Q

What is a Kochers incision?

A

Under right subcostal margin

Used for open cholecystectomy

362
Q

What is the name of the accessory bile duct which needs to be looked for when performing a cholecystectomy?

A

Duct of luschka present in 12-50% individuals

363
Q

Which investigation should be done to make a diagnosis of acalculous cholecystitis?

A

HIDA scan - assessment of emptying of gallbladder in response to stimulation to see if non functional
Ejection fraction less than 30% diagnostic

364
Q

What is a Rutherford Morrison incision?

A

Extraperitoneal approach to left or right lower quadrants

Gives access to iliac vessels and is approach of choice for first time renal transplant

365
Q

What is a BI RAD score?

A

Mammogram findings and results Breast Imaging Reporting and Data System sorts the results into categories numbered 0 through 6 to assess likelihood of cancer

366
Q

What features of an AKI make acute tubulointerstitial nephritis a likely cause?

A

Trigger - drugs or infections
Speed of deterioration
Eosinophilia

367
Q

Which ages of women are offered breast screening? And how often are they offered?

A

47-73

Every 3 years

368
Q

What is adsons sign?

A

Loss of radial pulse in arm by rotating head to ipsilateral side with extended neck following deep inspiration
Sign of thoracic outlet syndrome

369
Q

Why might a patient with Crohn’s disease get gallstones?

A

Bile salts absorbed in terminal ileum

Impairment of this process and therefore gallstones

370
Q

How long before surgery should the COCP be stopped?

A

4 weeks before and after restart 2 weeks after

371
Q

What is Meigs syndrome?

A

Triad of ascites, pleural effusion, and benign ovarian tumor

372
Q

When does duct ectasia commonly occur? What happens?

A

During breast involution that occurs during menopausal period
Ducts shorten and may contain insipidated material

373
Q

How does intraductal papilloma present?

A

Single duct discharge

Clear fluid which may be bloodstained

374
Q

Which drugs need to be stopped before surgery?

A
I LAC OA
Insulin
Lithium
Aspirin/anticoagulants
COCP
Oral hypoglycaemics
ACE inhibitors
375
Q

What is mondors disease of the breast?

A

Localised thrombophlebitis of a breast vein

376
Q

What are features of post thrombotic syndrome? What can be done to prevent it?

A
Painful heavy calves
Pruritus 
Swelling
Varicose veins
Venous ulceration 
Prevention: compression stockings offered to all patients with DVT
377
Q

What is may Thurner syndrome?

A

DVT of iliofemoral vein caused by compression of left common iliac vein by the overlying right common iliac artery

378
Q

What is Klippel trenaunay syndrome?

A

Triad of naevus flammeus, venous and lymphatic malformations and soft tissue hypertrophy of affected extremity

379
Q

What is Milroys disease?

A

Congenital lymphoedema caused by congenital aplasia of the lymphatic system

380
Q

What is the pathophysiology of rhabdomyolysis?

A

Low ATP production results in high intra cellular myocyte calcium concentrations which impair function and promote protease activity

381
Q

What are causes of pancreatitis?

A
I: idiopathic
G: gallstones
E: ethanol (alcohol)
T: trauma
S: steroids
M: mumps/ malignancy
A: autoimmune
S: scorpion stings/ spider bites
H: hyper-lipidaemia/Ca. /PTH (metabolic disorders)
E: ERCP
D: drugs
382
Q

How is a diagnosis of pancreatitis made?

A

2/3 of the following

  1. Abd pain- Acute onset, persistent, severe, epigastric pain often radiating to the back
  2. S. Amylase / Lipase 3x normal
  3. If not 3x, imaging (CECT/ MRI/ USS)
383
Q

What are the grades of severity of pancreatitis?

A

Mild acute pancreatitis: No organ failure, No local or systemic complications
Moderately severe acute pancreatitis: Organ failure that resolves within 48 h (transient organ failure) and/or Local or systemic complications without persistent organ failure
Severe acute pancreatitis: Persistent organ failure (>48 h), Single organ failure, Multiple organ failure

384
Q

What is the Glasgow prognostic score for pancreatitis?

A
PaO2: less than 8kPa
Age: over 55 years
Neutrophils: (WBC) over 15 x109/l
Calcium: less than 2mmol/l
Renal function: (Urea) over 16mmol/l
Enzymes: (AST/ALT) over 200 iu/l or LDH over 600 iu/l
Albumin: less than 32g/l
Sugar: (Glucose) over 10mmol/l
3 or more /8: Acute Severe pancreatitis 
2: Acute Moderate Pancreatitis
Less than 2: Acute Mild Pancreatitis
385
Q

What are poor prognostic features with pancreatitis?

A

Clinical impression of severity
Obesity
APACHE II over 8 in the first 24 hours of admission
CRP over 150 mg/l
Glasgow score 3 or more
Persisting organ failure over 48 hrs in hospital

386
Q

What are the 2 types of pancreatitis?

A
Interstitial oedematous pancreatitis (IEP)
Necrotising pancreatitis (NP)
387
Q

What are features of interstitial oedematous pancreatitis?

A

Diffuse inflammatory oedema of the pancreas
Contrast enhanced CT: Homogeneous enhancement and peri- pancreatic fat stranding +/- fluid collections
Resolves within a week

388
Q

What are features of necrotising pancreatitis?

A

About 5–10%
Parenchymal necrosis
Peripancreatic necrosis
Combined type (most common)
Contrast enhanced CT: Patchy enhancement. Over 1 wk, any non-enhancing area - pancreatic parenchymal/ peri-pancreatic necrosis
More morbid course; may remain solid/ liquefy, sterile/ infected, persist/ disappear

389
Q

What are the clinical phases of pancreatitis?

A

Early (1st week): systemic organ failure

Late (over 1st week): local complication / persistent systemic organ failure

390
Q

At what points does pancreatitis severity need reassessing?

A

Reassess at 24hrs, 48hrs and 7days after admission

391
Q

What are local and systemic complications of pancreatitis?

A

Local: (peri) pancreatic necrosis, sterile or infected
Systemic: organ failure, transient or persistent

392
Q

What are early and late local complications of interstitial oedematous pancreatitis?

A

Early (less than 4 weeks): APFC (acute peripancreatic fluid collection)
Late (over 4 weeks): Pancreatic pseudocyst

393
Q

What are early and late local complications of necrotising pancreatitis?

A

Early (less than 4 weeks): ANC (acute necrotic collection)

Late (over 4 weeks): WON (walled-off necrosis)

394
Q

What are diagnostic criteria for hereditary haemorrhagic telangiectasia?

A

Epistaxis
Telangiectases: lips, oral cavity, fingers, nose
Visceral lesions: GI, pulmonary AVM, hepatic AVM, cerebral AVM, spinal AVM
Family history: 1st degree relative
Need 2 for possible diagnosis, 3 for definite

395
Q

What are the management steps of pancreatitis?

A

Resuscitate
Risk Stratify
Prevent complications: Antibiotics, Enteral nutrition (NG feeds)
Remove gall stones: ERCP and Sphincterotomy and Stenting
Lap Chole (index admission / within 2 weeks of discharge)
Reduce Necrosis: HDU (Specialised centres with dedicated team)
If over 30% gd FNAC (7-14days), if infected, necrosectomy

396
Q

If a patient has a positive wells score (2 or more), what should be done to manage their DVT?

A

Doppler proximal leg USS within 4 hours

If can’t be arranged within 4 hours, should be given LMWH to cover until scan

397
Q

What is Meigs syndrome?

A

Benign ovarian tumour (usually fibroma) associated with ascites and pleural effusion

398
Q

What is the most common benign ovarian tumour in women under 25?

A

Dermoid cyst (teratoma)

399
Q

What is the most common cause of ovarian enlargement in women of a reproductive age?

A

Follicular cyst

400
Q

What is the hinchey classification for diverticular perforation?

A

1: para colonic abscess
2: pelvic abscess
3: purulent peritonitis
4: faecal peritonitis

401
Q

What is the management of diverticular disease?

A

Increase dietary fibre
Mild attack: antibiotics
Peri colonic abscess: surgical or radiological drainage
Recurrent: segmental resection
Hinchey 4: resection and stoma
Other perfs: laparoscopic washout and drain insertion

402
Q

What is the definition of toxic megacolon?

A

Transverse colon diameter >6cm

403
Q

How are flares of UC classified?

A

Mild: less than 4 stools/day, no systemic disturbance, normal ESR and CRP
Moderate: 4-6 stools, minimal systemic disturbance
Severe: more than 6 stools, blood, fever, tachycardia, abdo tenderness, distension, reduced bowel sounds, anaemia, hypoalbuminaemia

404
Q

What investigations need to be done for a patient presenting with an unprovoked DVT?

A
Routine bloods: FBC, calcium, LFT
Chest X-ray
Urinalysis 
Abdo pelvic CT/mammogram if over 40
Antiphospholipid antibodies 
Screen for hereditary thrombophilia if FH
405
Q

What is an anal fissure?

A

Longitudinal or elliptical tears of squamous lining of distal anal canal

406
Q

What is the difference between an acute and chronic anal fissure?

A

Less than 6 weeks acute

More than 6 weeks chronic

407
Q

What are risk factors for anal fissure?

A

Constipation
IBD
STIs: HIV, syphilis, herpes

408
Q

What is the management of an acute anal fissure?

A

Dietary advice: High fibre diet, high fluid intake
Bulk forming laxative
Lubricant before defecation
Topical anaesthetic

409
Q

What is the management of a chronic anal fissure?

A

Continue management of acute
Add topical GTN
If not effective after 8 weeks, secondary referral for surgery or Botox

410
Q

What caecal diameter is pathological?

A

> 8cm

411
Q

What amount of small bowel dilatation is pathological?

A

3cm or more

412
Q

What are the common causes of small bowel obstruction?

A

Hernia

Adhesions

413
Q

What amount of large bowel dilatation is pathological?

A

6cm or above

9cm caecum

414
Q

What are common causes of large bowel obstruction?

A

Cancer

Diverticular disease

415
Q

What is riglers sign?

A

Air on both sides of the bowel wall

416
Q

What is lead pipe colon a sign of?

A

Lead pipe colon

Prolonged inflammation - loss of haustral markings due to mucosal destruction

417
Q

What is thumb printing a sign of?

A

Inflamed haustra - chronic inflammation

418
Q

What is riglers triad?

A

SBO, pneumbilia, gallstone in RIF

Sign of Gallstone ileus

419
Q

What hormonal therapies are given for breast cancer?

A

ER/PR positive, Pre menopausal: tamoxifen for 5 years
Her 2 positive: herceptin
ER/PR positive, post menopausal: anastrozole (aromatase inhibitor)

420
Q

What are features of post thrombotic syndrome?

A
Painful heavy calves
Pruritus
Swelling
Varicose veins
Venous ulceration
421
Q

What should be done for patients with a DVT in order to reduce occurrence of post thrombotic syndrome?

A

Offer below knee graduated compression stockings with ankle pressure greater than 23mmHg a week after diagnosis or when swelling is reduced sufficiently, if there are no contraindications and:
Advise them to be worn for 2 years
Replace 2 or 3 times per year
Need to only be worn on affected leg

422
Q

What is a wells score?

A

Determine likelihood of DVT
Active cancer
Paralysis/immobilisation of lower extremities
Bedridden for 3 days or more or major surgery within 12 weeks
Localised tenderness along deep veins
Entire leg swollen
Calf swelling at least 3cm larger than asymptomatic side
Pitting oedema on symptomatic leg
Collateral superficial veins
Previous DVT
Alternative diagnosis at least as likely (-2)

423
Q

How does a wells score change management of a DVT?

A

DVT likely, score 2 or more: proximal leg vein USS within 4 hours and if negative, d dimer. If USS cannot be performed, d dimer and LMWH administered while waiting for scan
DVT unlikely, 1 point or less: d dimer, if positive arrange USS within 4 hours

424
Q

What is the management of DVT?

A

LMWH or fondaparinux given after diagnosis, continued for 5 days or until INR is above 2 for 24 hours
Warfarin given within 24 hours of diagnosis, continued for 3 months, consider longer if unprovoked and recurrence risk high (6 months)

425
Q

Which bugs cause acute cholecystitis?

A

E. coli
Klebsiella
Enterococci
Enterobacter

426
Q

What is leriche syndrome?

A

Atherosclerotic occlusive disease involving abdo aorta and of the iliac arteries
Claudication of buttocks and thighs
Atrophy of leg muscles
Impotence (due to L1 paralysis)

427
Q

What are indications for splenectomy?

A

Traumatic rupture
Haem: hereditary spherocytosis, thalassaemia, sickle cell, ITP, TTP
Malignancy: lymphoma, lymphoproliferative disorders
Cysts/abscess
Feltys syndrome
Gaucher’s disease
Splenic vein thrombosis

428
Q

What are the different categories of haemorrhoids?

A

First degree: bleeding no prolapse
Second: spontaneously reducible
Third: manual reduction required
Fourth: irreducible

429
Q

What is the mainstay of treatment for haemorrhoids?

A

Rubber band ligation

430
Q

What are complications of band ligation for haemorrhoids?

A
Band slippage
Ulcer
Urinary retention
Anal pain
Haemorrhage 
Infection
431
Q

What is the most effective way of treating haemorrhoids?

A

Open haemorrhoidectomy

432
Q

What are complications of open haemorrhoidectomy?

A
Pain
Bleeding
Urinary retention
Anal stenosis
Skin tags
Incontinence
433
Q

What are different categories of peri anal fistulae?

A

Type 1: intersphincteric
Type 2: transsphincteric
Type 3: extrasphincteric

434
Q

What are the aims of treatment for peri anal fistula?

A

Close fistula

Maintain continence

435
Q

What is a fistula seton?

A

Surgical thread left in fistula to keep it open, allowing it to drain and help it heal
Used in high and complex fistulas

436
Q

What is the difference between acute and chronic fissures?

A

Acute <6 weeks

437
Q

What drugs are used for chronic anal fissure?

A

GTN cream
Diltiazem
Botox

438
Q

Why do you not do a sphinceterotomy in women for anal fissure?

A

Shorter anal sphincter

Occult obstetric sphincter damage

439
Q

What are causes of pruritis ani?

A
Anal disease
Skin disease: psoriasis, eczema, thrush 
Threadworms
Allergy
Skin irritation: soaps, perfumes
Sweating
440
Q

What is APER?

A

Abdomino perineal excision of rectum

Used for anal/low rectal cancers

441
Q

What parts does a hernia consist of?

A

Neck

Sac

442
Q

Where is the femoral canal?

A

Most medial structure in the femoral triangle

443
Q

What are the boundaries of the femoral triangle?

A

Inguinal ligament
Sartorius
Adductor longus

444
Q

What are the boundaries of the femoral canal?

A

Anterior: inguinal ligament
Posterior: pectineal ligament
Laterally: femoral vein
Medial: lacunar ligament

445
Q

What are features of a saphena varix?

A

Soft and compressible
Disappears on lying down
Exhibits expansile cough impulse
Demonstrates fluid thrill

446
Q

Where can a hydrocoele occur in a female?

A

Canal of nuck

447
Q

What are indications for surgery in crohns?

A

Complications: abscess, perf, fistula, obstruction, bleeding
Failure of medical management
Intolerance of medical therapy
Neoplasia

448
Q

What is the string sign of Kantor?

A

Crohns: incomplete filling of intestinal lumen due to irritability and spasm associated with severe ulceration

449
Q

How many anastamoses are there in whipples procedure?

A

3

450
Q

Which AAA are considered high risk of rupture?

A

5.5cm or above
Rapidly enlarging >1cm/year
Symptomatic

451
Q

What is buergers test and buergers angle?

A

Angle: angle at which the foot goes pale when elevated in patient with PVD
Test: when leg goes pale, hang foot over edge of bed, if goes hyperaemic, buergers positive

452
Q

What classification system can be used for venous disease?

A

CEAP classification

453
Q

What are surgical treatments for varicose veins?

A

Endovenous treatment: endothermal ablation, foam sclerotherapy
Open vein surgery

454
Q

What is the definition of an aneurysm?

A

Vessel dilated to >2.5 times normal size

455
Q

Who gets AAA screening?

A

Men aged 65

USS

456
Q

What is the difference between an empyema and an abscess?

A

Empyema: collection of pus in already existing cavity eg pleural space
Abscess: collection of pus inside newly formed cavity