Surfactants Flashcards
1
Q
Clinical Indications for Exogenous Surfactants
A
- Prophylactic treatment of RDS in infants
- Rescue treatment
2
Q
Beractant
A
- Survanta
- prophylactic therapy in premature infants
3
Q
Calfactant
A
- Infasurf
- prophylactic treatment in premature infants less than 29 weeks
- rescue treatment
4
Q
Poractant alfa
A
Curosurf
- rescue treatment of infants
- unlabeled uses: severe MAS in term infants, resp. failure by group B strep in neonates
- 2.5 ml/kg, subsequent doses of 1.25 ml/kg given at 12-hr intervals
5
Q
Surfactant is produced by…, with the primary function of…
A
alveolar type II cells; regulating the ST forces of the liquid alveolar lining
6
Q
Surfactant is stored in….
A
lamellar bodies.
7
Q
Hazards and Complications of Surfactant Therapy
A
- airway occlusion, desaturation, and bradycardia
- high PaO2 values
- Overventilation and hypocarbia
- Apnea
- Pulmonary Hemorrhage
