suppressor of inhibition

Question 1

suppresses direct inhibition: it inhibits the action of some of the inhibitory transmitters on the neurons, especially the inhibitory effect of glycine in the spinal cord.

Answer 1

Strychnine

Question 2

suppresses presynaptic inhibition.

Answer 2

Picrotoxin

Question 3

bacterial toxin from Clostridium botulinum inhibits the release of acetylcholine from the nerve endings. It has been used experimentally to block neuromuscular transmission and in man causes the disease called ………………………

Answer 3

botulinism

Question 4

block the action of the enzyme cholinesterase, which is responsible for breaking down acetylcholine. This increases levels of acetylcholine in the synaptic cleft (the space between two nerve endings). The main use of ………… is for the treatment of dementia in patients with Alzheimer’s disease.

Answer 4

Cholinesterase inhibitors