Superficial Fungal Infections Flashcards

1
Q

Tinea Pedis Interdigital

A

Toe Web Infection

  • Most common, maceration appearance (soggy and wet), dry scaly fissure appearance
  • Itching
  • Must determine that bacteria is not the cause
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2
Q

Tinea Pedis Moccasin

A

Affects the soles of the feet
Appears: hyperkeratotic (thickening of soles), erthema, white and silver scales, entire sole is involved
- Hard to distinguish from xerosis, psoriasis, eczema

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3
Q

Tinea Pedis Inflammatory or bullous

A
Rare
Resembles allergic dermatitis
Starts as a web infection
Vesicles form on the soles of the feet --> bullae
Risk of secondary infection
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4
Q

Tinea Pedis Ulcerative Type

A

Invasive involvement of interdigital into the dermis
Maceration
Secondary infection

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5
Q

Tinea Pedis Dermatophytid

A

Hand Involvement

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6
Q

Tinea Pedis Treatment First Line

A

Topical therapy: If maceration or wet lesion are present –> aluminum acetate foot soaks (Burrows solution)
Oral: Griseofulvin (not used), Fluconazole, Terbinafine

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7
Q

Oral treatments

A

Reevaluate at end of each treatment phase

Baseline CBC and LFT; recheck after 1 month of treatment

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8
Q

Tinea Capitis

A

Ring worm of the scalp
Involves the scalp hair follicles and skin
Mainly school age kids and rare in adults
- Scalp alopecia (circular), black dot (broken off hair shafts), dandruff

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9
Q

Tinea Capitis Symptoms

A

Hair loss
Pain and tenderness
Flaking or scaling

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10
Q

Tinea Capitis Treatment

A
Ketoconazole shampoo
Topical antifungal solution and lotions
Selenium sulfide
Topical steroids
ORAL: Griseofulvin, fluconazole
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11
Q

Athlete’s Foot - Tinea Pedis

A

Fluconazole: 150 mg once a week for 1 month
Terbinafine: 250 mg per day for 2 weeks

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12
Q

Ring Worm- Tinea Capitis

A

Griseofulvin: 15 mg/kg/day for 6-8 wks or 330 mg QD for 4-6 wks
Fluconazole: 50 mg or 6 mg/kg/day for 4-6 wks or 8 mg/kg/day for 4-16 wks
Intraconazole: 5 mg/kg/day or 100 mg QD for 4-6 wks
Terbinafine: 125 or 250 mg for 4-6 wks

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13
Q

Tinea Barbae

A

Lesions involving the hair follicles of the beard and mustache

  • Animals = triggers
  • Symptoms: pruitus, tenderness and pain
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14
Q

Tinea Barbae Treatment

A

ORAL therapy bc topical cannot penetrate hair follicles

- Grisefulvin, fluconazole, Itraconazole, terbinafine

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15
Q

Tinea Corporis

A

“Ring Worm”

  • Circular lesions, demarcated borders
  • Triggers: humid climate, daycare, animals
  • Usually in trunk and limbs
  • Symptoms: mild pruritus
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16
Q

Tinea Corporis Treatment

A
Localized infections: topical antifungal therapy (twice daily and continue for 1 wk after resolution)
Aluminum acetate (wet lesions): apply dressing for 20-30 minutes 2-6 times per day
Oral (extensive infections)
17
Q

Tinea Corporis Oral

A

Fluconazole: 150 mg every week for 2-6 wks
Intraconazole: 100-200 mg QD for 2 wks
Terbinafine: 250 mg QD for 1-2 wks

18
Q

Tinea Cruris

A

Jock Itch
Triggers: warm/humid environment, tight/occlusive clothing, obesity
- Men
- High rate of relapse
- Demarcated scaling plaques, erythematous, bilateral
- Thing and groin region, buttocks, penis and scrotum (rare)

19
Q

Tinea Cruris Symptoms

A

Pruritus

Inflammation

20
Q

Tinea Cruris Treatment

A

Topical (first line): 2x daily for 10 days and even after they disappear
Powder: absorbs moisture (will not kill the fungi, just help)
Aluminum acetate solution
Topical steroids/antifunal combo: Lotrisone and Mycolog II
Oral: extensive

21
Q

Tinea Cruris Oral Treatment

A

Fluconazole: 150 mg every week for 2-4 wks
Terbinafine: 250 QD for 2-4 wks

22
Q

Tinea Manuum

A

Fungal infections of the hands
Thickened scaling skin on palms
ORAL better than topical

23
Q

Tinea Manuum Oral Treatment

A

Prevent onychomycosis or tinea pedis
Terbinafine: 250 mg QD for 14 days
Intraconazole: 200 mg QD for 7 days
Griseofulvin: 500 mg QD for 21 days

24
Q

Tinea Versicolor

A

Caused by yeast P. orbiculare (normal flora, within sweat glands)
Trigger: heat and humidity, Cushing’s disease, pregnancy, malnutrition, etc
- Circular macular patches of carious colors

25
Q

Tinea Versicolor Topical Treatment

A

Selenium sulfide (10 minutes daily for 7 days)
Ketoconazole, miconazole, clotriamizole, econazole (one to two times a day for 2-4 wks)
Keratolytic soaps

26
Q

Tinea Versicolor Systemic agents

A

Ketoconazole: 400 mg single dose or 200 mg QD for 5 days
Intraconazole: 200 mg daily for five days
Fluconazole: 300-400 mg as a single dose

27
Q

Topical agents indications and side effects

A

Tinea corporis, cruris, manuum, pedis (no follicule involvement)
Contact dermatitis

28
Q

Topical agents duration

A

Up to 2 wks

Terbinafine or luliconazole for 1 wks

29
Q

Topical agents disadvantages

A

Less effective for extensive infections or hyperkeratotic areas
Longer duration of therapy
Poor compliance
High relapse rate

30
Q

Topical Ointment formulation

A

Hyperkeratotic lesions

- Greasy, best absorptions, keeps moisture in

31
Q

Topical Lotions/Solutions formulation

A

Hairy areas of the body
Moist or weeping lesions
Prevent maceration

32
Q

Topical Creams Formulation

A

Scaling, dry lesions

33
Q

Topical powders formulation

A

Prevention- does not treat
Adjunctive therapy
Reduce maceration and moisture

34
Q

Topical Agents: Toinaftate (Tinactine)

A

No prescription
Cream, spray, powder solution, and ointment
Twice daily

35
Q

Topical Agents: Clotriamizole (Lotrimin)

A

No prescription
Cream, solution, lotion
Twice daily

36
Q

Topical Agents: Ketoxonazole

A

Yes prescription
Shampoo, cream
Once daily

37
Q

Topical Antifungals: Terbinafine (Lamisil)

A

No prescription
Cream, gel
QD or BID daily

38
Q

Luzu-Luliconazole

A

Tinea corporis, cruris and pedis
QD for 1 wk: cruris/corporis
QD for 2 wk: pedis
Cream, 60 grams