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Therapeutics P3S2 > Summary of Resistance Mechanism by Drug Class > Flashcards

Summary of Resistance Mechanism by Drug Class Flashcards

1
Q

Examples of Beta-lactams

A

Penicillins
Cephalosporins
Carbapenems
Monobactams

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2
Q

Examples of Aminoglycosides

A

Gentamycin
Tobramycin
Amikacin

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3
Q

Examples of Glycopeptides

A

Vancomycin

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4
Q

Examples of Lipopeptides

A

Daptomycin

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5
Q

Examples of Tetracyclines

A

Doxycycline

Minocycline

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6
Q

Examples of Glycylcycline

A

Tigecycline

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7
Q

Examples of Macrolides

A

Erythromycin
Azithromycin
Clarithromycin

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8
Q

Examples of Lincosamides

A

Clindamycin

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9
Q

Examples of Streptogramins

A

Quinupristin/dalfopristin

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10
Q

Examples of Oxazolidinones

A

Linezolid

Tedizolid

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11
Q

Examples of Fluoroquinolones

A

Ciprofloxacin
Levofloxacin
Moxifloxacin

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12
Q

Examples of Pyrimidines

A

Trimethoprim

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13
Q

Examples of Sulfonamides

A

Sulfamethoxazole

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14
Q

Examples of Rifamycins

A

Rifampin

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15
Q

Examples of Cationic peptides

A

Colistin

Polymyxin B

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16
Q 
Resistance Mechanism(s) of:
Beta-lactams
A

Hydrolysis (by beta-lactamase)
Altered target site
Efflux

17
Q 
Resistance Mechanism(s) of:
Aminoglycosides
A

Aminoglycoside-modifying enzymes
Altered target site
Efflux

18
Q 
Resistance Mechanism(s) of:
Glycopeptides
A

Altered cell wall precursors

19
Q 
Resistance Mechanism(s) of:
Lipopeptides
A

Altered target site

Thickening peptidoglycan structure

20
Q 
Resistance Mechanism(s) of:
Tetracyclines
A

Altered target site

Efflux

21
Q 
Resistance Mechanism(s) of:
Glycylcycline
A

Altered target site

Efflux

22
Q 
Resistance Mechanism(s) of:
Macrolides
A

Altered target site

Efflux

23
Q 
Resistance Mechanism(s) of:
Lincosamides
A

Altered target site

Efflux

24
Q 
Resistance Mechanism(s) of:
Streptogramins
A

Acetylation
Altered target site
Efflux

25
Q 
Resistance Mechanism(s) of:
Oxazolidinones
A

Altered target site

Efflux

26
Q 
Resistance Mechanism(s) of:
Fluoroquinolones
A

Altered target site

Efflux

27
Q 
Resistance Mechanism(s) of:
Pyrimidines
A

Altered target site

Efflux

28
Q 
Resistance Mechanism(s) of:
Sulfonamides
A

Altered target site

Efflux

29
Q 
Resistance Mechanism(s) of:
Rifamycins
A

ADP-ribosylation
Altered target site
Efflux

30
Q 
Resistance Mechanism(s) of:
Cationic peptides
A

Altered target site

Efflux

Therapeutics P3S2 (6 decks)

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