Summary Flashcards
Analeptics (Caffeine, Sulfhocamphocaine)
Drugs that have a direct effect in the RC
(acute poisoning with sleeping pills, anargesics, narcotics, local anestetics)
MA= relax the smooth muscles in the RT, dilate pulmonary arterioles & stimulates CNS
Antitussive (Codeine, Metylmorphine, Oxeladin, Prednoxdiasin)
Are drugs that suppress Cough center
(used to treat unproductive cough, thick sputum & intense debilitating cough)
MA= narcotics= supress cough reflex by acting in the cough center in the medulla
Non narcotics= suppress cough reflex by numbning the stretch receptors in RT & preventing the cough reflex from stimulated
Expectorants (Thyme Grass, plantain leaf, Terpinhydrate)
Are drugs that enhace the secretion of sputum & are used to remove the sputum from pulmonary tract
MA= the mecanism of action is based on the removal of secretion from RT by decrease viscosity with an increase in volume, increase secretion of mucous due to reflex irritation of the glands of bronchial mucosa
Reflex action= irritate receptors of gastric mucosa & reflexively (through vagus nerve) there is an increase in the separation of secretion in RT, Increase peristals of the bronchi & flickering cilia (which ensure discharge of sputum)
Mucolytics (Acetylcysteine, Ambroxol, Bromheine)
Agents that have a direct effect on bronchial mucosa & secretions contribute to dilution of sputum and its easier separation (decrease viscosity of sputum improve stiding throgh RT)
(Bronchopulmonary disease & Broncobstructive syndrome)
Bronchial Asthma (Salbutamol, Euphilin)
Allergic & infectious disease of bronchi
MA= BA leads to bronchial obstruction and increase sensibility of bronchi (hypereactivity) the # of mass cell increase, histamine release and vacular permeability increase.
Pulmonary Edema ( Stropantin)
drugs that decrease the pressure caused offluid in lungs and heart
(acute heart failure, severe intoxication, lung lessions with chemicals, infectous disease)
MA= As a result of stagnation of blood, blood plasma passed throgh the wall of alveoli to lumen alveoli, where up to 100-200ml of liquid can accumulate, foam is formed when breathing and hypoxia occurs