Sulfonylureas Flashcards
1
Q
What is the brand name of glyburide?
A
Brand = Diabeta and Micronase
2
Q
What is the brand name of glipizide?
A
Brand = Glucotrol and Glucotrol XR
3
Q
What is the brand name of glimepiride?
A
Brand = Amaryl
4
Q
What is the mechanism of action of glyburide, glipizide, and glimepiride?
A
It inhibits the sulfonylurea receptor on the beta cells (on/near the ATP-sensitive K+ channels); remember - this will close the K+ channels allowing the beta cell to depolarize opening the Ca2+ channels to enter the beta cell and eventually release insulin
5
Q
Do sulfonylureas depend on glucose in order to work?
A
NO
