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Pharm III > Sulfonamides and Trimethoprim > Flashcards

Sulfonamides and Trimethoprim Flashcards

1
Q

TMP-SMX Absorption

A

IV and PO

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2
Q

TMP-SMX Distribution

A

Prostate

PENETRATES CSF

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3
Q

TMP-SMX Elimination

A

Liver and kidney elimination

Need to adjust for renal insufficiency patients

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4
Q

TMP-SMX Uses

A

UTI Savior

Prostatitis

Skin infections due to MRSA

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5
Q

TMP-SMX Side Effects

A

Leukopenia, Thromobcytopenia, megaloblastic anemia

Hypersensitivity Rash (Stevens-Johnson)
- Similar to eripsyelaa

Crystalluria

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6
Q

TMP-SMX Drug Interactions

A

Phenytonin- increases levels

Warfarin- Increases anticoagulant effect

Methotrexate- decreases renal clearance

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Pharm III (8 decks)

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