Sulfonamides Flashcards

1
Q

Sulfonamides Description

A

By-product of the dye prontosil rubrum.

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2
Q

Sulfonamides Distribution

A

readily absorbed from GI tract, distributed through all body tissues, enter CSF, pleural fluid, and synovial fluid

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3
Q

Sulfonamides Elimination

A

eliminated through glomerular filtration and hepatic metabolism

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4
Q

Sulfonamides Mechanism of Action

A

inhibiting the incorporation of para-aminobenzoic acid, a basic building block of bacteria.

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5
Q

Sulfonamides Clinical uses

A

treating ulcerative colitis, and in combination with other drugs for UTIs, pneumonia, toxoplasmosis, and resistant gram-negative infections.

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