Sulfonamides Flashcards
1
Q
Sulfonamides Description
A
By-product of the dye prontosil rubrum.
2
Q
Sulfonamides Distribution
A
readily absorbed from GI tract, distributed through all body tissues, enter CSF, pleural fluid, and synovial fluid
3
Q
Sulfonamides Elimination
A
eliminated through glomerular filtration and hepatic metabolism
4
Q
Sulfonamides Mechanism of Action
A
inhibiting the incorporation of para-aminobenzoic acid, a basic building block of bacteria.
5
Q
Sulfonamides Clinical uses
A
treating ulcerative colitis, and in combination with other drugs for UTIs, pneumonia, toxoplasmosis, and resistant gram-negative infections.