Sulfanomides Flashcards
0
Q
Sulfadiazine
A
Sulfonamide
Combine w/ pyrimethamine for toxoplasmosis
Inc risk of crystalluria
1
Q
Co-trimoxazole
TMP-SMX
A
Sulfanomide - Trimethoprim (selective inhibitor of dihydrofolate reductase, only in combo, teratogen) + sulfamethoxazole
DOC: uncomplicated UTI (not enterococci), moraxella catarrhalis, otitis media
2nd line: Listeria (1st ampicillin)
also: URI, pneumocystis jiroveci, shigellosis, salmonella, UTIs, prostatitis, non-TB mycobacteria
2
Q
Silver Sulfadiazine
A
Sulfonamide
Topical for burns
3
Q
Pyrimethanine + Sulfadoxine
A
Sulfonamide - Presumptive tx of malaria (nor prophylaxis)
Pyrimethamine: inhibits dihydrofolate reductase
Sulfadoxine: antagonizes PABA