Sulfanomides Flashcards

0
Q

Sulfadiazine

A

Sulfonamide
Combine w/ pyrimethamine for toxoplasmosis
Inc risk of crystalluria

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1
Q

Co-trimoxazole

TMP-SMX

A

Sulfanomide - Trimethoprim (selective inhibitor of dihydrofolate reductase, only in combo, teratogen) + sulfamethoxazole
DOC: uncomplicated UTI (not enterococci), moraxella catarrhalis, otitis media
2nd line: Listeria (1st ampicillin)
also: URI, pneumocystis jiroveci, shigellosis, salmonella, UTIs, prostatitis, non-TB mycobacteria

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2
Q

Silver Sulfadiazine

A

Sulfonamide

Topical for burns

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3
Q

Pyrimethanine + Sulfadoxine

A

Sulfonamide - Presumptive tx of malaria (nor prophylaxis)
Pyrimethamine: inhibits dihydrofolate reductase
Sulfadoxine: antagonizes PABA

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