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Pharm Exam 7 > Cephalosporins > Flashcards

Cephalosporins Flashcards

0
Q

Cefadroxil monohydrate

A

1st gen cephalosporin - oral
good G+, moderate G-
DOC: E. coli, Klebsiella pneumo, Proteus
Not: enterococci, MRSA or MRS epi

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1
Q

Cefazolin

A

1st gen cephalopsorin - Surgical prophylaxis
good G+, moderate G-
DOC: E. coli, Klebsiella pneumo, Proteus
Not: enterococci, MRSA or MRS epi

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2
Q

Cephalexin

A

1st gen cephalopsorin - oral
good G+, moderate G-
DOC: E. coli, Klebsiella pneumo, Proteus
Not: enterococci, MRSA or MRS epi

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3
Q

Cefoxitin

A

2nd gen cephalosporin

DOC: E. coli, Klebsiella, Proteus, Moraxella catarrhalis

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4
Q

Cefaclor

A

2nd gen cephalosporin
DOC: E. coli, Klebsiella, Proteus, Moraxella catarrhalis
Serum sickness

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5
Q

Cefuroxime

A

2nd gen cephalosporin

DOC: E. coli, Klebsiella, Proteus, Moraxella catarrhalis

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6
Q

Cefotetan

A

2nd gen cephalosporin
DOC: E. coli, Klebsiella, Proteus, Moraxella catarrhalis
Disulfiram effect w/ EtOH

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7
Q

Cefprozil

A

2nd gen cephalosporin

DOC: E. coli, Klebsiella, Proteus, Moraxella catarrhalis

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8
Q

Loracarbef

A

2nd gen cephalosporin

DOC: E. coli, Klebsiella, Proteus, Moraxella catarrhalis

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9
Q

Cefotaxime sodium

A

3rd gen cephalosporin - more active enterobacteriaceae
CNS penetration
DOC: Moraxella catarrhalis, Salmonella

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10
Q

Ceftizoxime

A

3rd gen cephalosporin - more active enterobacteriaceae
Antipseudomonal
DOC: Moraxella catarrhalis, Salmonella

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11
Q

Ceftazidime

A

3rd gen cephalosporin- more active enterobacteriaceae
Antipseudomonal
DOC: Moraxella catarrhalis, Salmonella

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12
Q

Ceftriaxone

A

3rd gen cephalosporin- more active enterobacteriaceae - parenteral
CNS penetration - Substantial hepatic elimination
DOC: Moraxella catarrhalis, Salmonella AND Neisseria gonorrhoeae AND PCN-resistant Strep pneumoniae

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13
Q

Cefixime

A

3rd gen cephalosporin- more active enterobacteriaceae
DOC: Moraxella catarrhalis, Salmonella AND Neisseria gonorrhoeae
oral

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14
Q

Cefpodoxime

A

3rd gen cephalosporin- more active enterobacteriaceae

DOC: Moraxella catarrhalis, Salmonella

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15
Q

Cefditoren

A

3rd gen cephalosporin- more active enterobacteriaceae

DOC: Moraxella catarrhalis, Salmonella

16
Q

Ceftibuten

A

3rd gen cephalosporin- more active enterobacteriaceae

DOC: Moraxella catarrhalis, Salmonella

17
Q

Cefdinir

A

3rd gen cephalosporin- more active enterobacteriaceae

DOC: Moraxella catarrhalis, Salmonella

18
Q

Cefepime

A

4th gen cephalosporin
More resistance to B-lactamase
better G+/G-
Antipseudomonal

19
Q

Ceftarolime fosamil

A

Unnamed gen cephalosporin - high affinity for PBP-2a
Effective against MRSA
No antipseudomonal

20
Q

Cephalosporins are not effective against

A

Enterococci
Listeria
MRSA (except ceftarolime)
Atypicals (Chlamydia, Mycoplasma)

21
Q

Cephalosporins DOC

A

Moraxella catarrhalis - 2nd or 3rd gen
Neisseria gonorrhoeae - ceftriaxone, cefixime (3rd gen)
E. coli, Klebsiella, Proteus - 1st or 2nd gen
Salmonella - 3rd gen
Penicillin resistant Strep pneumoniae - Ceftriaxone

Pharm Exam 7 (5 decks)

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