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SBL Exam 1 > Subtypes & Characteristics of ACh receptors > Flashcards

Subtypes & Characteristics of ACh receptors Flashcards

1
Q

M1
Location:
Receptor:
Mechanism:

A

Nerves
GPCR, Gq/11
IP3, DAG cascade

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2
Q

M2
Location:
Receptor:
Mechanism:

A

Heart, nerves, smooth m.
GPCR, Gi/o
Inhibition of cAMP production, activation of K+ channels

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3
Q

M3
Location:
Receptor:
Mechanism:

A

Glands, smooth m., endothelium
GPCR, Gq/11
IP3, DAG cascade

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4
Q

M4
Location:
Receptor:
Mechanism:

A

CNS
GPCR, Gi/o
inhibition of cAMP production

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5
Q

M5
Location:
Receptor:
Mechanism:

A

CNS
GPCR, Gq/11
IP3, DAG cascade

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6
Q

Nm
Location:
Receptor:
Mechanism:

A

skeletal muscle, neuromuscular junction
Pentamer a2bd & g/e
Na+, K+ depolarizing channel

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7
Q

Nn
Location:
Receptor:
Mechanism:

A

Postganglionic cell body, dendrites, CNS
a & B only
Na+, K+ depolarizing channel

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SBL Exam 1 (4 decks)

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