Direct-acting cholinomimetics

Question 1

Acetylcholine

Answer 1

approved for intraocular use during surgery & causes miosis (reduction in pupil size)

Question 2

Methacholine

Answer 2

administered for diagnosis of bronchial airway hyperactivity who do not have apparent asthma

Question 3

Bethanechol

Answer 3

urinary retention & heartburn

selective mAChR agonist

Question 4

Carbachol

Answer 4

nonspecific cholinergic agonist that is used for treatment of glaucoma or to produce miosis during surgery or ophthalmic exam

Question 5

Cevimeline

Answer 5

used to treat dry mouth in patients’ with Sjogren syndrome

Question 6

Pilocarpine

Answer 6

xerstomia treatment in patients with Sjogren’s syndrome or head & neck cancer treatment related xerostomia (PO), miosis during ophthalmic procedures (topical) & glaucoma (topica)

Question 7

Varenicline

Answer 7

approved for smoking cessation

partial agonist for high affinity & selectivity to a4B2 nicotinic acetylcholine

Question 8

approved for intraocular use during surgery & causes miosis (reduction in pupil size)

Answer 8

Acetylcholine

Question 9

administered for diagnosis of bronchial airway hyperactivity who do not have apparent asthma

Answer 9

Methacholine

Question 10

urinary retention & heartburn

selective mAChR agonist

Answer 10

Bethanechol

Question 11

nonspecific cholinergic agonist that is used for treatment of glaucoma or to produce miosis during surgery or ophthalmic exam

Answer 11

Carbachol

Question 12

used to treat dry mouth in patients’ with Sjogren syndrome

Answer 12

Cevimeline

Question 13

xerstomia treatment in patients with Sjogren’s syndrome or head & neck cancer treatment related xerostomia (PO), miosis during ophthalmic procedures (topical) & glaucoma (topica)

Answer 13

Pilocarpine

Question 14

approved for smoking cessation

partial agonist for high affinity & selectivity to a4B2 nicotinic acetylcholine

Answer 14

Varenicline (Chantix)