Substance Jeopardy

Question 1

Opioids +UA

Answer 1

up to 12-36hrs after

Question 2

Hep C

Answer 2

90% of pts who inject opioids

Question 3

IV opiate users risk

Answer 3

bacterial endocarditis
HIV
Hepatitis
TB

Question 4

Hallucinogen Phencyclidine intoxication

Answer 4

psychosis
anxiety
delirium
mood dz (bipolar, depressive)

pupil dilation

NO withdrawal
(inhalants - no withdrawal)

Question 5

Stimulant Cocaine intoxication

Answer 5

pupil dilation
induce sexual dysfunction
delirium
psychotic dz

anxiety
OCD
sleep
mood dz (bipolar, depressive)

Question 6

Naloxone

narcan

Answer 6

opioid antagonist challenge

Question 7

Opioid withdrawal

Answer 7

pupil dilation
piloerection
fever
dysphoria
N/V
muscle aches
lacrimation/rhinorrhea
sweating
ANXIETY

Question 8

Suboxone

Answer 8

Naloxone + buprenorphine

Question 9

Opioid intoxication

Answer 9

pupil constriction
drowsiness/coma
impaired attention
slurred speech

induce sleep disorders
sexual dysfunction
delirium
depressive dz

Question 10

PCP intoxication

Answer 10

+UDA

similar to stimulant intoxication BUT ROTARY NYSTAGMUS

Question 11

cocaine + alcohol

Answer 11

DEC insomnia

DEC nervousness

Question 12

amphetamine + sedative/marijuana

Answer 12

DEC insomnia

DEC nervousness

Question 13

stimulant withdrawal

Answer 13

bradycardia

anxiety
OCD
sleep
mood dz (bipolar, depressive)

Question 14

+stimulant test

Answer 14

up to 90 days - hair sample

Question 15

cocaine

Answer 15

fast onset - Inhalation, IV

INC glutamate, dopamine

Question 16

speedball

Answer 16

cocaine + heroin

Question 17

Alcohol

Operant Conditioning

Answer 17

+ Positive Reinforcement
buzz/high
NO + reinforcement = tolerance

• Negative reinforcement: alcohol use to prevent alcohol withdrawal

Question 18

substance induced disorders

Answer 18

resolve within 1 month after cessation

Question 19

Alcohol prevalence

Answer 19

Males 12% (2x)
Females 5%

3-4x INC if +family hx

Question 20

Alcohol and Asians

Answer 20

Alcohol metabolizing enzyme genetic polymorphisms

AE: flushing, palpitations, & possibly more severe reactions in asians when they consume alcohol

Low risk of alcohol use disorders

Question 21

Heavy Drinking LABS

Answer 21

GGT (gamma-glutamyltransferase)
CDT (carbohydrate-deficient transferrin)

MCV - not useful to monitor bc long T1/2 of RBCs

Question 22

Co-morbid alcohol use disorder

Answer 22

Bipolar
Schizophrenia
Anti-social Personality Disorder

Question 23

Brain circuitry changes

Answer 23

present after detox

Question 24

social impairment

Answer 24

Criteria A
failure to fulfill major obligations at work, home or school

continued use despite persistent or recurring interpersonal problems

Question 25

impaired control

Answer 25

Criterion A: taking substance larger amounts or over longer time period than intended Spending great deal of time obtaining, using or recovering from substance use Cravings desire to cut down or unsuccessful attempt decrease/stop use

Question 26

Pharmacological Criteria

Answer 26

refers to "putting up" with tolerance and withdrawal

Question 27

risky use

Answer 27

physically hazardous situations or continued use despite knowledge the substance is causing or worsening medical problem

Question 28

Caffeine

Answer 28

sleep disorder | anxiety

Question 29

Marijuana intoxication

Answer 29

anxiety sleep disorders psychotic disorder

Question 30

sedative/hypnotic intoxication

Answer 30

``` psychosis bipolar depressive sleep sexual dysfunction delirium neurocognitive dz NOT anxiety ```