Substance Abuse Flashcards
Up to __% of patients seen in an ambulatory may have associated substance abuse
20%
About __% of american will show clinical dependence on a non-tobacco substance at some point in their lifetime
24.8%
Are substance abuse disorders more common in men or women?
Men
Intoxication associated with __% of MVAs, DV cases, and murders.
50%
T/F: Addiction is a diagnostic term according to DSM-5
False
It is not
How are substance abuse disorders defined in DSM-5?
Any inappropriate use of a substance versus previous definitions that separated this into abuse versus dependence
_________ is defined as a reversible syndrome due to the recent use of substance
Intoxication
_______ is defined by the following…..
1) Need to use an increased amount of a substance in order to achieve the desired effect
2) Markedly diminished effect with continued use of the same amount of the substance
Tolerance
________ is defined as normal function only becomes possible with active use of a substance, and cessation of this substance causes adverse physiological consequences.
Dependence
_______ is defined as a cluster of symptoms with an onset closely following the cessation (or reduction in dose) that is specific to a drug (or drugs). Symptoms can be both physiological and cognitive
Withdrawal
What is the name of the questionnaire used in assessing alcohol dependence?
CAGE Questionnaire
Should you complete a mental status examination when working up substance abuse?
Yes
What co-morbid conditions are likely to accompany a patient with a substance abuse disorder?
Depression
Anxiety
Personality Disorder
Why are the following ordered (to rule in/out) when working up Alcohol Abuse….
CBC
CMP
Thiamine
CBC - Anemia, Bone Marrow Depression
CMP - Liver Function
Thiamina - Wernicke’s Encephalopathy
Which of the following would NOT be considered a direct diagnostic test for alcohol abuse
A) A blood alcohol level in excess of 300 mg/dL
B) A blood alcohol level of greater than 150 mg/dL without gross evidence of intoxication
C) A blood alcohol level of 100 with evidence of clinical intoxication
D) A blood alcohol level of greater than 100 mg/dL upon routine examination indicates alcoholism with a high degree of reliability
C) A blood alcohol level of 100 with evidence of clinical intoxication
What are EARLY manifestations of chronic alcoholism with underlying organ disease?
Rosacea Palmar erythema Palpable liver from fatty liver disease Respiratory infections Easy bruising
What are LATE manifestations of chronic alcoholism with underlying organ disease?
Caput medusae
Ascites
Jaundice
Esophageal varices/hemoptysis/hematochezia
To be diagnosed with an alcohol use disorder…..
A patient must exhibit signs/symptoms/behaviors over a ___ _______ period
12 Month Period
An uncomplicated withdrawal (“Shakes”) typically onsets when?
Peaks when?
Subsides when?
Onset: 7-38 hours after cessation
Peak: 24-48 Hours
Subsides: 5-7 Days
What manifestation during a alcohol withdrawal period would be indicative of marked, chronic alcohol abuse?
Seizures
A patient may develop alcoholic hallucinosis how long after cessation of alcohol?
What types of hallucinations may occur?
Can these be permanent?
Within 48 hours of cessation
Hallucinations can be auditory, visual, or tactile
These can sometimes become permanent
What is the most severe form of alcohol withdrawal?
Delirium Tremens
What are clinical manifestations of delirium tremens?
Confusion Agitation Mild fever Nausea Irritability Tremor Autonomic hyperarousal*
T/F: Delirium Tremens is NOT a medical emergency
False
It is
T/F: Delirium Tremens can progress to cardiovascular collapse
True
What medication class is commonly used in alcohol withdrawal?
Benzodiazepines