Substance Abuse Flashcards
What is Intoxication?
Reversible effect of a Subtance affecting physiology and reasoning
What is Withdrawl?
Opposite effect of drug. Decline in tissue concentrations after prolonged heavy use
What is Tolerance?
Decreased effects of a substance with repeated use
What is Risky Use?
Health Consequence from use >14 drinks/wk for men
>7 drinks/wk for women
What is Addiction?
Physical Dependance on a substance
What is Substance Misuse?
Abuse in the content of Precription drugs
What are the diagnostic Criteria of a subtance use disorder?
Clinical Distress/Impairment 12 mon period >2 items from Crit A Mild => Severe Specifiers -Early remission -Sustained remission -Maint Therapy -In a controlled Envt
What are the GI Complications of Alcohol use?
Gastritis, Esophagitis, Pancreatitis, Fatty liver/hepatitis Stomach/Duodenal Ulcers Malabsorption Mallory Weiss Tears Esophageal varices Malignancy
What are the CSN Complications of Alcohol use?
Dec Abstract thinking Impaired Learning Wernicke's encephalopathy Fetal Alcohol Synd Withdrawl Seizures Coma Subs induced Neurocog Dis Blackouts
What is the CIWA protocol for Assess and Tx of Alcohol Withdrawl?
N/V, Anxiety, Sweats, Tactile Dist
Add Scores, Total + Sx =>Tx
Monitor 72hrs w/ score
What are intoxication Sx of Alcohol?
30-50 Buzz 50 Euphoria 100 Ataxia/Slurred Speech 200 Drowsy/Confused 300 Stuperous >400 Progressive coma/death
What are intoxication Sx of Caffeine?
Restless, Nervous, Excitement, Insomnia, Flushed face, Diuresis
What are intoxication Sx of Cannabis?
Conjunctival Injection Inc appetitie Dry Mouth Tachycardia Innapropriate Laughter
What are intoxication Sx of Hallucinagens? (PHENCYCLIDINE)
VIOLENT BEHAVIOR belligerence Impaired Judgement Nystagmus Hypertension
What are intoxication Sx of Inhalents?
NYSTAGMUS, Dizziness, Incoordination, Slurred Speech, Unsteady Gait, Arrhythmia
What are intoxication Sx of Opioids?
Pupillary Const + Slurred speech, drowiness, impairment
Euphoria => Apathy, dysphoria, psychomotor agitation/ retardation
What are intoxication Sx of Sed/Hyp/Anxiolytics?
Sexual/Agressive Beh, mood lability, imp judgement
Slurred Speech, Incoordination, unsteady gait
Looks like EtOH intox
Flumazenil
What are intoxication Sx of Stimulants?
Euphoria w/ vigor
Hyperactive
Pupillary Dilation
Tachy/Bradycardia
Where is Dopamine Made?
Ventral Tegmental Area
What is the MOA of Cocaine?
A Dopamine Reuptake inhibitor
What are the Traits of Wernicke Korsakoff syndrome?
Vitamin B1 Def (Thiamine) Triad of: Confusion, Ataxia, Ocular Abn Memory loss Confabulation Inability to form new memories Hallucinations
What are the Maint Thx for Alcohol Use disorder?
Naltrexone: Opioid antagonist
-Vivitriol is Extended form
Acaprosate: GABA and Glut
Disulfiriam: Accum of Acetaldehyde
What are signs of Caffeine withdrawl?
Headache Fatigue/Drowsy Dysphoric Flu-Like Sx Difficulty Conc
What are signs of Synthetic Canabinoid Intoxication?
Psychosis. Anxiety, Irritability
What is the Maint Thx for opioid use disorder?
Methadone: LA Opioid Agonist
Buprenorphine: Synth Part Ag
Naltrexone: Synth Ant
What are the results of long term use of Stimulants?
Chaotic Beh
Social Isolation
Sexual Dysfunction
Aggressive Beh
What are the withdrawl symptoms of Tobacco?
Irritation, Frustration, Anger, Anxiety, Dec Conc, Inc App,
What are the Treatments of Tobacco abuse?
Beh Thx, Hypnosis, Nicotene Replacement, Buproprion, Varenicline
What are the Stages of Tx of a substance abuse disorder?
Detoxification
Medically managed withdrawl
Short/long term residential
Counseling, AA
