Substance 1 Jeopardy

Question 1

Opioids can be detected thru a urine drug test for this many hours after administration of the opioid.

Answer 1

12-36 hours

Question 2

This type of liver disease may occur in up to 90% of persons who inject opioids.

Answer 2

Hepatitis C

Question 3

HIV, hepatitis, tuberculosis, and this cardiac related condition are serious medical problems for IV opiate users.

Answer 3

Bacterial endocarditis

Question 4

This physical sign of opiate withdrawal is also “seen” in hallucinogen intoxication and stimulant intoxication.

Answer 4

Pupil dilation

Question 5

Opioid intoxication may be diagnosed by administering this opioid antagonist challenge.

Answer 5

Naloxone (Narcan)

Question 6

These 2 sx are a/w more severe opiate withdrawal and are often not seen in routine clinical practice.

Answer 6

Piloerection and fever

Question 7

Suboxone is a combination of these two medications.

Answer 7

Naloxone (Narcan) + buprenorphine

Question 8

This one is not part of opiate withdrawal.

Answer 8

Lightheadedness

Withdrawal: dysphoria, N/V, muscle aches, lacrimation/rhinorrhea, pupil dilation/piloerection, fever, sweating

Question 9

Signs of opioid intoxication are pupil constriction, drowsiness/coma, impaired attention or memory, and this.

Answer 9

Slurred speech

Question 10

This can differentiate PCP intoxication and stimulant intoxication from each other

Answer 10

What is a urine drug test?

Clinical picture is similar, though rotary nystagmus may be seen in PCP intoxication but not stimulant

Question 11

Cocaine users often use sedative substances–most often this substance–to reduce insomnia, nervousness, and other unpleasant side effects.

Answer 11

Alcohol

Question 12

Amphetamine-type stimulant users often use sedative substances–most often this substance–to reduce insomnia, nervousness, and other unpleasant side effects.

Answer 12

Marijuana

Question 13

This sign is often present and is a reliable measure of stimulant withdrawal.

Answer 13

Bradycardia

Question 14

BD, schizophrenia, other substance use disorders, and this personality disorder in particular are risk factors for stimulant use disorder.

Answer 14

Antisocial personality disorder

Question 15

This type of sample can be used to detect use of a stimulant up to 90 days after use.

Answer 15

Hair sample

Question 16

These two forms of cocaine administration have the most rapid onset of action.

Answer 16

Inhalation and injection

Question 17

A speedball is the combination of cocaine and this drug.

Answer 17

Heroin

Question 18

Cocaine increases the levels of what two NT’s?

Answer 18

Glutamate and dopamine

Question 19

In terms of operant conditioning, the alcohol induced buzz/high is this; also tolerance results in the lack of this.

Answer 19

Positive reinforcement

Question 20

In terms of operant conditioning, consuming alcohol to stave off alcohol withdrawal symptoms results in this.

Answer 20

Negative reinforcement

Question 21

Most substance-induced disorders resolve within this amount of time after the cessation of acute withdrawal, the cessation of severe intoxication, or the use of the substance.

Answer 21

1 month

- Most improve within days to weeks of abstinence

Question 22

The prevalence of alcohol use disorder in this sex is twice as much as the other.

Answer 22

Males (12% vs. 5% females)

Question 23

For an individual who has a close relative (parent) with an alcohol use disorder, their risk is this many times higher than normal.

Answer 23

3-4x

Question 24

Alcohol metabolizing enzyme genetic polymorphisms result in flushing, palpitations, and possibly more severe reactions in individuals of this race when they consume alcohol

Answer 24

Asians

- Japanese, Chinese, and Koreans are at lower risk for Alcohol Use Disorders

Question 25

Elevations in these 2 lab test results are sensitive indicators of ongoing heavy drinking and can be used to monitor abstinence.

Answer 25

• Gamma-glutamyltransferase (GGT)

- Carbohydrate-deficient transferrin (CDT)

Question 26

While elevation of GGT, CDT, and this test indicates a history of heavy drinking, GGT and CDT test may also be useful in detecting a relapse to heavy drinking, but this test is not.

Answer 26

MCV

- Not useful for monitoring due to long T1/2 of RBCs

Question 27

The patients with BD, schizophrenia, and this personality disorder have a markedly high rate of co-morbid alcohol use disorder.

Answer 27

Antisocial personality disorder

Question 28

Substance use disorder pts, especially those with severe disorder, have an underlying change in this which persists even beyond detoxification.

Answer 28

Brain circuitry

Question 29

Continued use despite persistent or recurring interpersonal problems.

Answer 29

Social impairment

Question 30

A desire to cut down or unsuccessful attempts to decrease or stop use refers to this Criterion A.

Answer 30

Impaired control

Question 31

Pharmacological criteria (of Criteria A) refers to “putting up” with these two phenomenon.

Answer 31

Tolerance and withdrawal

Question 32

Taking the substance in larger amounts or over a longer time period than intended refers to this Criterion A

Answer 32

Impaired control

Question 33

Use in physically hazardous situations or continued use despite knowledge the substance is causing or worsening a medical problem is called this.

Answer 33

Risky use

Question 34

Spending a great deal of time obtaining, using, or recovering from the substance use refers to this Criterion A.

Answer 34

Impaired control

Question 35

Failure to fulfill major obligations at work, home, or school refers to this Criterion A.

Answer 35

Social impairment

Question 36

Craving refers to this Criterion A.

Answer 36

Impaired control

Question 37

Caffeine intoxication may induce a sleep disorder or this type of substance-induced disorder.

Answer 37

Anxiety

Question 38

Marijuana intoxication may induce anxiety disorders, sleep disorders, and this type of substance-induced disorder.

Answer 38

Psychotic disorder

Question 39

The hallucinogen phencyclidine may induce psychotic disorders, anxiety disorders, delirium, and this type of substance-induced disorders.

Answer 39

Mood disorders (both bipolar and depressive)

Question 40

Opioid intoxication may induce sleep disorders, sexual dysfunction, delirium, and this type of substance-induced disorder

Answer 40

Depressive disorders

Question 41

Opioid intoxication will not, but opioid withdrawal may induce this type of substance-disorder.

Answer 41

Anxiety

Question 42

Alcohol and sedative/hypnotic intoxication may both induce the same type of substance disorders except sedative/hypnotic intoxication will NOT induce this.

Answer 42

Anxiety

Both: Psychotic, Bipolar, Depressive, Sleep, Sexual dysfunction, Delirium, Neurocognitive disorders

Question 43

Intoxication, but not withdrawal, of stimulants such as cocaine may induce sexual dysfunction, delirium, and this type of substance-induced disorder.

Answer 43

Psychotic disorders

Question 44

Intoxication and withdrawal of stimulants such as cocaine may induce, anxiety, OCD, sleep, and this type of substance-induced disorder.

Answer 44

Mood (both bipolar and depressive)

Question 45

Inhalants and this type of substance do not cause a withdrawal.

Answer 45

Hallucinogens