Substance 1 Jeopardy Flashcards
Opioids can be detected thru a urine drug test for this many hours after administration of the opioid.
12-36 hours
This type of liver disease may occur in up to 90% of persons who inject opioids.
Hepatitis C
HIV, hepatitis, tuberculosis, and this cardiac related condition are serious medical problems for IV opiate users.
Bacterial endocarditis
This physical sign of opiate withdrawal is also “seen” in hallucinogen intoxication and stimulant intoxication.
Pupil dilation
Opioid intoxication may be diagnosed by administering this opioid antagonist challenge.
Naloxone (Narcan)
These 2 sx are a/w more severe opiate withdrawal and are often not seen in routine clinical practice.
Piloerection and fever
Suboxone is a combination of these two medications.
Naloxone (Narcan) + buprenorphine
This one is not part of opiate withdrawal.
Lightheadedness
Withdrawal: dysphoria, N/V, muscle aches, lacrimation/rhinorrhea, pupil dilation/piloerection, fever, sweating
Signs of opioid intoxication are pupil constriction, drowsiness/coma, impaired attention or memory, and this.
Slurred speech
This can differentiate PCP intoxication and stimulant intoxication from each other
What is a urine drug test?
Clinical picture is similar, though rotary nystagmus may be seen in PCP intoxication but not stimulant
Cocaine users often use sedative substances–most often this substance–to reduce insomnia, nervousness, and other unpleasant side effects.
Alcohol
Amphetamine-type stimulant users often use sedative substances–most often this substance–to reduce insomnia, nervousness, and other unpleasant side effects.
Marijuana
This sign is often present and is a reliable measure of stimulant withdrawal.
Bradycardia
BD, schizophrenia, other substance use disorders, and this personality disorder in particular are risk factors for stimulant use disorder.
Antisocial personality disorder
This type of sample can be used to detect use of a stimulant up to 90 days after use.
Hair sample
These two forms of cocaine administration have the most rapid onset of action.
Inhalation and injection
A speedball is the combination of cocaine and this drug.
Heroin
Cocaine increases the levels of what two NT’s?
Glutamate and dopamine
In terms of operant conditioning, the alcohol induced buzz/high is this; also tolerance results in the lack of this.
Positive reinforcement
In terms of operant conditioning, consuming alcohol to stave off alcohol withdrawal symptoms results in this.
Negative reinforcement
Most substance-induced disorders resolve within this amount of time after the cessation of acute withdrawal, the cessation of severe intoxication, or the use of the substance.
1 month
- Most improve within days to weeks of abstinence
The prevalence of alcohol use disorder in this sex is twice as much as the other.
Males (12% vs. 5% females)
For an individual who has a close relative (parent) with an alcohol use disorder, their risk is this many times higher than normal.
3-4x
Alcohol metabolizing enzyme genetic polymorphisms result in flushing, palpitations, and possibly more severe reactions in individuals of this race when they consume alcohol
Asians
- Japanese, Chinese, and Koreans are at lower risk for Alcohol Use Disorders
Elevations in these 2 lab test results are sensitive indicators of ongoing heavy drinking and can be used to monitor abstinence.
- Gamma-glutamyltransferase (GGT)
- Carbohydrate-deficient transferrin (CDT)
While elevation of GGT, CDT, and this test indicates a history of heavy drinking, GGT and CDT test may also be useful in detecting a relapse to heavy drinking, but this test is not.
MCV
- Not useful for monitoring due to long T1/2 of RBCs
The patients with BD, schizophrenia, and this personality disorder have a markedly high rate of co-morbid alcohol use disorder.
Antisocial personality disorder
Substance use disorder pts, especially those with severe disorder, have an underlying change in this which persists even beyond detoxification.
Brain circuitry
Continued use despite persistent or recurring interpersonal problems.
Social impairment
A desire to cut down or unsuccessful attempts to decrease or stop use refers to this Criterion A.
Impaired control
Pharmacological criteria (of Criteria A) refers to “putting up” with these two phenomenon.
Tolerance and withdrawal
Taking the substance in larger amounts or over a longer time period than intended refers to this Criterion A
Impaired control
Use in physically hazardous situations or continued use despite knowledge the substance is causing or worsening a medical problem is called this.
Risky use
Spending a great deal of time obtaining, using, or recovering from the substance use refers to this Criterion A.
Impaired control
Failure to fulfill major obligations at work, home, or school refers to this Criterion A.
Social impairment
Craving refers to this Criterion A.
Impaired control
Caffeine intoxication may induce a sleep disorder or this type of substance-induced disorder.
Anxiety
Marijuana intoxication may induce anxiety disorders, sleep disorders, and this type of substance-induced disorder.
Psychotic disorder
The hallucinogen phencyclidine may induce psychotic disorders, anxiety disorders, delirium, and this type of substance-induced disorders.
Mood disorders (both bipolar and depressive)
Opioid intoxication may induce sleep disorders, sexual dysfunction, delirium, and this type of substance-induced disorder
Depressive disorders
Opioid intoxication will not, but opioid withdrawal may induce this type of substance-disorder.
Anxiety
Alcohol and sedative/hypnotic intoxication may both induce the same type of substance disorders except sedative/hypnotic intoxication will NOT induce this.
Anxiety
Both: Psychotic, Bipolar, Depressive, Sleep, Sexual dysfunction, Delirium, Neurocognitive disorders
Intoxication, but not withdrawal, of stimulants such as cocaine may induce sexual dysfunction, delirium, and this type of substance-induced disorder.
Psychotic disorders
Intoxication and withdrawal of stimulants such as cocaine may induce, anxiety, OCD, sleep, and this type of substance-induced disorder.
Mood (both bipolar and depressive)
Inhalants and this type of substance do not cause a withdrawal.
Hallucinogens
