Subject Matter Requirements Flashcards
Mitosis: Period of cell growth before the DNA is duplicated
G1: Growth part of Interphase
Mitosis: Period when the DNA is duplicated (that is, when chromosomes are duplicated)
S: Synthesis part of Interphase
Mitosis: Period after DNA is duplicated; cell prepares for division
G2: Final preparations for division part of Interphase
Mitosis phases
PMAT - Prophase, Metaphase, Anaphase, Telophase
Mitosis: “pairing” - chromosomes pair in preparation for division
Prophase
Mitosis: “middle” - chromosomes line up on the mid-line of the cell
Metaphase
Mitosis: “away” - the chromatids are pulled away from each other by the spindle fibers attached to the centrioles
Anaphase
Mitosis: “two” - two new cells are formed, as well as the nuclear membranes
Telophase
Structure of the cell membrane:
form bilayer
Phospholipids
Structure of the cell membrane:
strengthens membrane
Cholesterol
Structure of the cell membrane:
let in selected molecules and ions
Protein channels
Characteristics of the cell membrane:
controls what enters and exits the cell
Semi-permeable
Characteristics of the cell membrane:
has water-proof middle with water interactive top and bottom
Hydrophobic / hydrophilic
Characteristics of the cell membrane:
bilayer is contiguous with vesicles and membranes of organelles, can be folded onto itself to allow endocytosis and exocytosis
Self-assembly
Methods of transport across the membrane:
random mixing due to kinetic energy of molecules/ions
Diffusion
Methods of transport across the membrane:
diffusion of water across a membrane
Osmosis
Methods of transport across the membrane:
ATP adds energy to move the molecules / ions
Active Transport
Methods of transport across the membrane:
membrane encloses around something outside the cell
Endocytosis
Methods of transport across the membrane:
specific case endocytosis, membrane encloses around food, “cell eating”
Phagocytosis
Methods of transport across the membrane:
specific case of endocytosis, membrane encloses around water, “cell drinking”
Pinocytosis
Methods of transport across the membrane:
membrane releases something to the outside of the cell
Exocytosis
Role of semipermeable membranes in cellular communication:
signal “same” or “intruder”, accept hormone signals
Surface proteins
Role of semipermeable membranes in cellular communication:
offer sites for cells to share materials
Junction
Role of semipermeable membranes in cellular communication:
space between nerve cells and neuromuscular junctions
Synapses
Role of semipermeable membranes in cellular communication:
fine strands of cytoplasm extending through pores in cell walls of plants
Plasmodesmata
What completes the synthesis of proteins?
Endoplasmic reticulum
What packs the proteins and tags them to go to other parts of the cell, organ or organism?
Golgi apparatus
Role of chloroplasts in obtaining and storing usable energy:
uses light energy to convert ADP + P to ATP
Photophosphorylation
Location of the Krebs cycle
Mitochondrial matrix
Where phosphorylation takes place - yielding large amounts of ATP
Mitochondrial cristae
What increases the rate of exergonic reactions by lowering activation energy?
Enzymes
Factors that affect enzyme activity:
the complexity of the enzyme and substrate, and the specificity of the binding site, will affect how well the enzyme binds with the substrate and/or similar substrates
Levels of protein organization
Factors that affect enzyme activity:
_____ denatures proteins and causes enzymes to lose their shape. _____ slows the kinetic activity of the molecules decreasing the likelihood of them coming in contact.
Heat / Cold
Factors that affect enzyme activity:
Salts can affect the same of the enzyme because of the positive and negative charges.
Ionic conditions
Factors that affect enzyme activity:
____________ of enzyme and substrate - one or the other becomes a limiting factor.
Concentration
Factors that affect enzyme activity:
Extremes in ____ and ____ denature the enzyme
pH - acid / base
Metabolism of macromolecules:
Macromolecules are broken down to monomers as in cellular respiration.
Catabolic pathways
There is a decrease in free energy because the stored energy in the large molecule is released and is no longer available to do work.
The reaction is exergonic because energy is released when the bonds that hold the molecule together are broken.
Metabolism of macromolecules:
Monomers are joined together to make macromolecules as in photosynthesis.
Anabolic pathways
There is an increase in free energy because energy is stored in the bonds used to make the macromolecule and becomes available to do work.
The reaction is endergonic because energy is stored when bonds are formed.
_________ blood from the body returns to the heart through veins and is then pumped to the lungs where oxygen is exchanaged for carbon dioxide in the capillary beds of the alveoli.
Deoxygenated
_________ blood is pumped back to the hear (from the alveoli) and out to the body to supply oxygen to the tissues.
Oxygenated
Food is chewed by teeth and swallowed with saliva into the esophagus.
Bolus
The stomach adds acid and churns the food until it is liquefied.
Chime
Some digestive enzymes are added in the mouth and the stomach, but the majority of the enzymes necessary for chemical digestion are excreted in the _________.
Small intestine
Fully digested particles are absorbed through the wall of the small intestine into ____________.
The capillary beds surrounding them
The blood stream carries the __________, ___________, and __________ to the cells of the body.
lipids, carbohydrates, and amino acids
Nitrogenous waste from the breakdown of proteins is released by the cells into the blood stream.
Waste removal
__________ are sent from a nerve receptor into the spinal cord and brain.
Afferent signals
__________ are sent from the brain to the peripheral body.
Efferent signals
Internal environment:
sense pressure
Baroreceptors
Internal environment:
sense chemical concentrations, acid/base, hormones
Chemoreceptors
Internal environment:
sense temperature
Thermoreceptors
Internal environment:
sense touch pressure, sstretching, sound waves, motion
Mechanoreceptors
External environment receptors
Mechanoreceptors, thermoreceptors and sense organs
Self-regulated, independent of external environment, internal environment maintained within certain parameters
Homeostasis
What maintains the water and mineral balance in the body?
Kidneys
What maintains the fluid pressure and oxygen concentration in the body?
Heart
What collects information from all the internal and external sensors, monitors the information and sends messages to the other system to collaborate body functions?
Brain
What supports and protects the internal organs, moves the body in conjunction with muscles and are connected at the joints by ligaments?
Bones
What lies between bones to cushion joints?
Cartilage
What are connected to bones by tendons?
Muscle
Sliding of ______ and _______ in myofibrils cause contraction of muscle fibers that together form a contraction in a muscle.
Myosin / actin filaments
Physiology of the Immune System:
protection by skin, mucous membranes, tears, saliva, inflammation, histamine response, complement system
Non-specific Responses
Physiology of the Immune System:
Humoral response and Cell-mediated response
Specific Responses
Antibodies bind to antigen and trigger a response to it.
Antibody-mediated response
They activate helper T cells.
Antibodies
Cause plasma B cells to produce antibodies
Antibody-mediated response
Cause memory B cells to be produced so that the reaction time will be reduced the next time that specific antigen is encountered.
Antibody-mediated response
T-Cells that display the antigen and trigger a response to it
Cell-mediated response
Vaccination relies on the production of ____________.
Memory B cells
The individual receiving the vaccination must have _________ or no antibodies will be made, or the vaccine may make them contract the disease.
functional immune system
The vaccine must have enough DNA from the _________ to trigger an antibody response, but not so much as to initiate the disease process.
Pathogen