Subcortical Areas Of The Brain Flashcards

1
Q

What are basal nuclei

A

Caudate nucleus
Putamen
Globes pallidus
Subthalamic nucleus
Substantia nigra

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2
Q

Where are the basal nuclei located

A

Collection of nucleus deep to the white matter of cerebral cortex

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3
Q

Striatum =

A

Caudate nucleus + putamen

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4
Q

Caudate nucleus + putamen =

A

Striatum

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5
Q

Describe caudate nucleus and putamen

A

Separated by ant. Limb of internal capsule
Both input nuclei to the basal nuclei
Receive excitatory input

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6
Q

Describe globes pallidus

A

Can be subdivided ; externa (Gpe) and interna (Gpi)
Output nucleus of basal nuclei
Both parts fucntionally different with different connections

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7
Q

Lentiform nucleis =

A

Globus pallidus + putamen

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8
Q

Subthalamic nucleus

A

Receives Afferent from the cortex and other basal nucleu structures
Output excitatory to globus pallidus and substantia nigra

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9
Q

Substantia nigra

A

In rostral midbrain
Dopaminergic neurons project to striatum and subthalamic nucleus

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10
Q

Describe the limbic system

A

Structures referred to as limbic lobe
Ring of cortex spanning frontal, parietal & temporal lobes
Influence ANS, endocrine secretions, emotional behaviour

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11
Q

What are the structures in the limbic system

A

Structures include:
• Subcallosal gyrus
• Cingulate gyrus
• Parahippocampal gyrus
• Hippocampal formation
• Amygdaloid nucleus
• Mammillary bodies
• Ant. Thalamic nucleus

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12
Q

What are the 3 parts of the hippocampus/hippocampal formation

A

Subiculum
Hippocampus proper (Ammon horn)
Dentate gyrus

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13
Q

Describe ht hippocampus

A

Hippocampus and subiculum fibres form fimbria becoming fornix (output pathway)
Send fibres to entorhinal cortex
Neurogenesis occurs in dentate gyrus
Hippocampus - memory

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14
Q

Describe the amygdala

A

Afferent include visual, somatosensory, gustatory and olfactory, thalamus and cortical
Plays a role in emotions, emotional memory and learning, fear and related behaviours and reward
If damaged normal facilitation of attention and memory of emotional stimuli affected

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15
Q

What does the Diencephalon consist of

A

Thalamus, hypothalamus, epithalamus

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16
Q

Describe the structure of the Diencephalon

A

Located between the brainstem and the cerebral hemisphere
Continuous with the rostral part of the midbrain
Forms the lateral wall of the 3rd ventricle

17
Q

Describe the thalamus

A

2 thalami n eon each side of the 3rd ventricle
Connected by iterthalamic connection
Receives and processes all information coming from the cerebrum
Subcortical structures project to the cortex via thalamus
Mediates emotional response, arousal and emotion

18
Q

Describe the input o the thalamus

A

Specific (drivers) information that must be forwarded to the cortex
Regulatory (modulators) modulate and regulate what is sent to the cortex

19
Q

What are the functional nuclei of the thalamus

A

Relay - motor, sensory and limbic
Association - connect with cortex
Other- connect with basal nuclei, limbic system, reticular nucleus

20
Q

What are relay nuclei in thalamus

A

Sensory relay nuclei
Input related to sensory receptors
MGN - medial geniculate nucleus
LGN - lateral geniculate nucleus

21
Q

What are relay nuclei in thalamus

A

Input related to motor areas
VA - ventral anterior nucleus
VL - ventral lateral nucleus

22
Q

Limbic relay nuclei in thalamus

A

Anterior nucleus ANT input from ipsilateral mammillary body, relayed to cingulate cortex and prefrontal and parietal cortices
Lateral dorsal nucleus LD input from entorhinal cortex relayed to cingulate and prefrontal and parietal cornices

23
Q

What are limbic association nuclei in thalamus

A

Dorsomedial nuclei - connections throughout the limbic system

24
Q

Association nuclei in thalamus Diencephalon

A

Pulvinar (PUL) – reciprocal extensive connections
• Receives input from retina & visual assoc. areas to integrate and evaluate. Visuospatial working memory
• Related to auditory processing, coordinates and engages areas important in language
Dorsomedial nucleus
• Afferent fibres from basal nuclei & amygdala also
• Plays a role in limbic circuit of motivational & emotional aspects of behaviour

25
Q

Association nuclei

A

Modulators in interactions of one part of the cortex with another

26
Q

Intralaminar nuceli

A

Centromedian (CM) & Parafasicular (PF) nuclei
• Play a role in arousal and in facilitating awareness & vigilance.
• Connections to striatum suggest a role in facilitating goal orientated behaviour

27
Q

Thalamus reticular nucleus

A

Sheet of neurons surrounding the thalamus
Modulate excitatory projections between the thalamus & cortex influencing the flow of information from the thalamus

28
Q

What is the hypothalamus

A

Floor of Diencephalon
Attached to pituitary gland at ventral side by infundibulum, penetrated by 3rd ventricle
Main homeostatic centre, direct contact with blood, monitors everything, secretes hormones

29
Q

What nuclei does hypothalamus house

A

• Supraoptic
• Paraventricular
• Ventromedial
• Suprachiasmatic
• Dorsomedial
• Arcuate
• Tuberal

30
Q

Afferent connections of hypothalamus

A

General somatic, visceral, gustatory
Limbic system
Olfactory information
Thalamohypothalamic
Retinohypothalamic

31
Q

Efferent connections of the hypothalamus

A

Descending to visceral motor nuclei via brainstem and spinal cord (sympathetic and parasympathetic nuclei and ganglia)
Ascending to the thalamus

32
Q

What is the epithalamus

A

Forms the roof of the Diencephalon
Consists of:
-pineal gland (plays a role in circadian rhythm)
-habenular nucleus (centre for integration for olfactory, visceral and somatic efferent pathways)