Cranial Nerves Flashcards
Describe upper motor neuron
Usually located in the cerebral cortex
Axons project to owner motor neurons in brain stem and spinal cord
Describe location of lower motor neurons
Usually located in brain stem or spinal cord
Damage to upper motor neuron results in..
Paresis or paralysis
Spastic paralysis
Exaggerated tendon reflexes
Damage to lower motor neuron results in…
Paresis or paralysis
Flaccid paralysis
Loss of tendon reflexes
Rapid muscle atrophy of affected muscles
Fasciculation
Describe 1st to 3rd order neuron
1st - arise in cerebral cortex
2nd - internuncial, grey column of SC
3rd - lower MN in ant. Grey column
Describe the corticobulbar tract
Arises mainly in the lateral aspect of the primary motor cortex
• Synapse with cranial nerve nuclei. Most innervate cranial nerve nuclei bilaterally
• Unilateral innervation to the area of the facial nerve nuclei which supplies the muscles of the lower quadrant of the face
Fibre types of cranial nerves
Efferent motor fibres
Afferent sensory fibres
3 types of efferent fibres
General somatic efferents (GSE)
• Cell bodies in brainstem
• Innervate skeletal muscle derived from somites (III, IV, VI, XII)
Special visceral / Branchial motor efferents (SVE)
• Functionally identical to GSE
• Cell bodies in brainstem and innervate skeletal muscle derived from pharyngeal arches
• Visceral = in less developed animals (fish) pharyngeal arches give rise to smooth muscle or glands (V, VII,
IX, X, XI)
General visceral efferent (GVE)
• Cell bodies within brainstem – parasympathetic
• Innervate smooth muscles or glands (III, VII, IX, X)
Describe the Afferent fibres
General somatic afferents (GSA)
• Cell bodies outside the CNS (ganglia)
• From joint, tendon, skin, muscle
• Pain, temperature, proprioception, touch and pressure
• Innervate specific nuclei in brainstem (V, VII, IX, X)
Special somatic afferents (SSA)
• Similar to GSA
• Transmit specialised sensory inputs e.g. sight, hearing (II, VIII)
Special visceral afferents (SVA)
• Similar to SSA
• Take information from chemoreceptors associated with viscera and senses e.g. taste and smell (I, VII, IX, X)
General visceral afferents (GVA)
• Receptors located in serous lining or smooth muscle of body viscera
• thirst, hunger, visceral pain, chemoreception (VII, IX, X)
Describe the Olfactory nerve (CN1)
Sensory
Special sensory Afferent SVA fibres
Cell bodies in olfactory epithelium of nasal mucosa - no ganglion
Axons transmitted through cribriform plate of ethmoid bone to olfactory bulb
Postsynaptic fibres of secondary neurons form olfactory tract
Complex communication network sending fibres to autonomic centres and limbic system
Function : sense of smell
Describe the optic nerve CN2
Sensory
Special sensory Afferent SSA fibres
Cell bodies in retina (first order) and retinal ganglia (second order)
Myelinated second order axons grouped together as the optic nerve and leave orbit via optic canal
Terminate in lateral geniculate body of thalamus and protectable area of midbrain
Cells in lateral geniculate body form geniculocarine tract, travel to primary visual cortex
Function: vision
What are the cranial nerves of the midbrain
Oculomotor 3
Trochlear 4
Describe the oculomotor nerve 3
Motor
General somatic efferents:
• Emerges from the midbrain
• All extraocular (skeletal) muscles except lateral rectus and superior oblique
• Control eye movements
• Also levator palpebrae superioris (elevates upper eyelid)
• From oculomotor motor nucleus
General visceral efferents:
• Parasympathetic
• Constrict pupils via sphincter pupillae and ciliary (smooth) muscles
• From Edinger-Westphal nucleus
• Sympathetic fibres leave ciliary ganglion with post ganglionic parasympathetic fibres
• Terminate in ciliary body
• Pupillary light and accommodation reflex
Parasympathetic effect on iris
Sphincter pupillae muscle contracts: pupil size decreases
Sympathetic effect on iris
Dilator pupillae muscle contracts
Pupil size increases