Study Study guide wink wink Flashcards

1
Q

Cyclophosphamide

A

bladder toxicity
drink 2L per day
use emetic

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2
Q

Cisplatin

A

extravasation!
hard on vessels, IV access
sodium __________

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3
Q

Antimetabolite

A

decreases folic acid
teratogenic - methotrexate

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4
Q

Tamoxifen

A

double glove
decrease estrogen
bone density

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5
Q

cytoprotectants

A

prevent side effects of chemo

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6
Q

Epoetin alpha

A

increase RBC

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7
Q

Filgrastim

A

WBC

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8
Q

Leukovorin

A

folic acid (methotrexate)

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9
Q

Oprelvkin

A

increase platelet

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10
Q

Tumor Lysis Syndrome

A

HYPER Kalem Calc Uric Phos
HYPO Calcium Mag

TREAT WITH FLUID

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11
Q

Antibiotics - general principles

A

Start broad (not for long r/t superinfection risk)
Take ALL doses (r/t residual bacteria)

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12
Q

Superinfection

A

kills normal flora

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13
Q

Opportunistic

A

immunocompromised (HIV)

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14
Q

Aminoglycosides

A

GNATS
Gentamycin - oto/nephrotoxic
Cardiac edema, peripheral neuropathy, herpes
NARROW TI (trough and peak)
CANNOT GIVE PENICILLIN
(one hour pre/post)

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15
Q

Cephalosporin

A

AE: bleeds, CBC, anti-coagulated patients

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16
Q

Aztreonam

A

Dilator –> mucolytic –> Az

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17
Q

Penicillin

A

Hypersensitivity
NO cyclo/cephalosporin
Interstital nephritis!! (inflammed tubules)

PEN G ACCIDENTALLY GIVEN CAN CAUSE CARDIAC ARREST

18
Q

Fluoroquinolone

A

(Flozins)
Tendinitis (tendon rupture)
Weakness
Hyper/hypoglycemia
Photosensitivity
QT prolongation

19
Q

Macrolides

A

Eyrthromycin, azithromycin
Hepatotoxic, pseudo colitis, QT prolong

INTERACTS with warfarin/dig

20
Q

Fluconazole + Diltiazem

A

CARDIAC DEATH

21
Q

Clindamycin

A

FATAL PSEUDOMEMBRANOUS COLITIS

22
Q

Lipoglycopeptide

A

Vancomycin
Nephrotoxic (amino +vanc)
Only certain doses peripheral
NARROW TI- trough before 4th dose
RED MAN SYNDROME

23
Q

Linezolid

A

Not long term (bone marrow suppression)
Cannot give with antidepressants (r/t serotonin syndrome)

24
Q

Chloramphenicol

A

blood dyscrasia (aplastic anemia PERMENANT) (bleeds)

25
Q

Daptomycin

A

NO STATIN

26
Q

Sulfonamides

A

Hypersensitivity
Photosensitivity
Steven Johnson Syndrome

27
Q

Tetracycline

A

EMPTY STOMACH W WATER
UPRIGHT FOR 30m (ESOPHAGITIS)
expired –> renal failure
teeth discoloration under 8yr
harms bone growth
photosensitivy

28
Q

Urinary antiseptics

A

Phenazopyridine
orange urine - no UA
longer than two days renal failure (JAUNDICE SERIOUSLY)

29
Q

TB meds

A

Rifampin - orange +stains
INH - liver toxic - neuropathy B6
Pyrazinamide - hyperuricemia (finish GOUT)
Ethambutol - optic neuritis (red/green)

30
Q

Herpes

A

FAV
Famciclovir Aciclovir Valacyclvoir
thrombocytopenic purpura (decrease platelet causes bleeding) (red tiny dots)

31
Q

Cytomegalovirus

A

Ganciclovir
bone marrow supressant
birth defects - HCG pre/post

32
Q

Oseltamivir

A

take within 48hr within symptoms of flu

33
Q

RSV

A

Ribavirin
Inhaled - extremely teratogenic (NO PREGGO IN ROOM)

34
Q

Hepatitis B/C

A

pancreatitis

35
Q

HIV drugs

A

cannot miss a dose!

36
Q

Antifungals

A

Amphotericin B (BIG INFECTION
cardiac death
only compatible with dextrose
NO AMINOGLYCO
hard on vein (phleb risk)
Lipid form in renal patient

37
Q

Glycoizil

A

hepatic necrosis (liver toxic(

38
Q

Echinocandin

A

Assess duration
binds to albumin

39
Q

Terbinafine

A

hepatotoxicity

40
Q

Malaria

A

QUINN
take drug pre/post exposure

41
Q

amebicides

A

hard on liver (NO ALC)
flush,sweat

42
Q

Lindaine

A

CNS –> seizure precaution