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Pharm 2 > final > Flashcards

final Flashcards

1
Q

Clomiphene Citrate

A

Infertility
one year after failed trying
drug dependent
multiple birth
hot flash

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2
Q

Magnesium sulfate

A

Tocolytics - inhibit labor

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3
Q

Oxytocin

A

Induce labor
Stop postpartum hemorrhage

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4
Q

Metclopramide

A

Induce lactation

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5
Q

Estrogen

A

replacement
safe for osteoporosis
clots, dementia, antibiotic/anti-seizure meds decrease

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6
Q

Progestin

A

inhibit ovulation, amenorrhea
clots

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7
Q

Testosterone

A

Endometriosis
Fibrocystic breast

reproductive effects

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8
Q

Slidenafil

A

20-26m onset
ED
HA, cardiac conditions, Nitrate

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9
Q

Alprostadil

A

immediate onset

Burning/fibrosis

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10
Q

Finasteride

A

6-12mo onset
BPH

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11
Q

Tamsulosin

A

Immediate onset relaxation of prostate
BPH

Orthohypo

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12
Q

Epoetin Alpfa

A

Hematopoietic stimulation
RBC production
Need iron + V C
NO HBG <12
MI HTN

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13
Q

Filgrastim

A

Stim bone marrow

Bone paine

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14
Q

Interferon Alfa 2b

A

Immune stimulation

hematologic, autoimmune/ fatal infection

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15
Q

Aldesleukin

A

Immune stimulation
increase T cells

anaphylaxis, severe hypotension

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16
Q

Methotrexate/Mycophenolate

A

Immune suppression

infection, maligancy, pregnancy

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17
Q

Cyclosporine

A

immune suppressant
anti-rejection

HTN, nephrotoxic, infection, cancer

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18
Q

Adalimumab

A

suppress immune, decrease inflammation

pulmonary edema, fluid retention

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19
Q

Abatacept

A

immune suppressant
prevent cytokines

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20
Q

Acetaminophen

A

fever and pain

Liver failure 4g dose, acetylcystine antidote

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21
Q

Aspirin

A

pain/antiplatelet

GI bleed, hold 1wk pre/post op, give with food

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22
Q

NSAIDs

A

Meloxicam, Ibuprofen, Celecoxib, Indomethacin

GI/MI

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23
Q

Colchicine

A

GOUT
decrease crystal

Hepatotoxic

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24
Q

Allopurinol

A

GOUT
reduce acid

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25
Q

Prednisone

A

Corticosteroid
broad spectrum

hyperglycemia, fluid retention, no live vaccine, taper off dose

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26
Q

Levothyroxine

A

Hypothyroid
increase metabolic rate

hyperthyroid, AM on empty stomach, 0.5-4.2mc

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27
Q

PTU

A

Hyperthyroid

liver failure, hypothyroid

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28
Q

Iodine solution

A

Hyperthyroid
pre-op

staining

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29
Q

Somatropin

A

Growth deficiency
stim growth

hyperglycemia, muscle pain, closed epiphysis

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30
Q

Desmopressin

A

Diabetes Insipidus

Cardiac arrest, hyponatremia

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31
Q

Leuprolide

A

Precocious Puberty
decrease testosterone

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32
Q

Octreotide

A

Acromegaly
inhibit growth hormone

Hyperglycemia

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33
Q

Alendronate

A

hypercalcemia

bind to bone and block calcium release

esophageal irritation/erosion, inability to sit upright for 30 minutes, full glass water

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34
Q

Hydrocortisone

A

Addison’s disease

hyperglycemia, HTN, vertigo, before 0900

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35
Q

Fludrocortisone

A

Addison’s disease

HTN, CHF, growth suppression, hyperglycemia, hypokalemia

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36
Q

Ketoconazole

A

Cushing’s
inhibit cortisol

itchy, liver toxic, acidic liquid

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37
Q

Phenobarbitol

A

Seizure
Barbituates

Steven-Johnsons
Suicidal ideation

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38
Q

Lorazepam

A

Seizure
Benzodiazepine
status epilepticus

R depression

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39
Q

Gabapentin

A

Seizure/Nerve pain

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40
Q

Phenytoin

A

Seizure
10-20mcg

Gingival hyperplasia
IV tissue toxic

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41
Q

Carbamazepine

A

Epilepsy

Aplastic anemia, Agranulocytosis

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42
Q

Valproate

A

Seizure

Pancreatitis, Alt clot time, teratogenic

43
Q

Acetazolamine

A

Seizure
Diuretic action

44
Q

Dantrolene

A

Spasm/Spasticity

Fatal liver impairment

45
Q

Morphine Sulfate

A

antitussive, HF, PE

IV- 10-20 min
5ml/5min

Naloxone reversal

46
Q

Butorphanol

A

opioid agonist/antagonist
pre-op/labor pain

47
Q

Naloxone

A

opioid antagonist

immediate withdrawal
short half life

48
Q

Lidocaine

A

topical
most painful site
increase systemic w epi

49
Q

Isoflurane

A

inhaled general anesthetic
!MH
dantrolene OD

50
Q

Propofol

A

IV GA
Rapid induction, <1min
allergy to soy, egg, preserves

51
Q

Vecronium

A

Neuromuscular GA
relax/intubate
3-5min, 25-40min

52
Q

Midazolam

A

Benzo, GA

Flumazenil antidote

53
Q

Fentanyl

A

adjuvant med

Naloxone

54
Q

Ergotamine

A

migraine

no antifungal/antibiotic

55
Q

sumatriptan

A

migraine

56
Q

Imipramine

A

Tricyclic Antidepressant
block reuptake of norepi
2-6hr at HS
more toxic

57
Q

Fluoxetine/Venla

A

SSRI
ocd, bulimia

seratonin syndrome

58
Q

Phenelzine

A

MAOI
increases epi

HTN crisis, no tyramine, no ssri

59
Q

Bupropin

A

aytipical antidepressant
CNS effects
neuropsychiatric reaction when smoke cessation

60
Q

Lithium

A

Bipolar

metallic taste, hand tremor
no diuretics

61
Q

Haloperidol

A

first gen antipsychotic
IV 10-15 with 1.5in IM

Tardive dyskinesia, akathisia, dystonia, parkinsons, prolog QT

62
Q

Clozapine

A

second gen antipsychotic

increase death in dementia, hyperglycemia

63
Q

Dextroamphetamine

A

ADHD

misuse can cause sudden death or serious CV events

64
Q

Methylphenidate

A

ADHD
no TCA

65
Q

Atomoxetine

A

ADHD
low risk abuse, suicidal ideation

66
Q

Guanfacine

A

ADHD
Antihypertensive
Gi/CV 2 weeks

67
Q

Chlordiazepoxide

A

Benzo for recovery

HTN crisis, hyperpyrexia, agitation

68
Q

Methadone

A

Substance abuse
prevent withdrawal

69
Q

Naltrexone

A

Substance abuse
reduce cravings

70
Q

cyclophosphamide

A

cancer
bladder toxicity (2L)

71
Q

Cisplatin

A

Cancer
watch for extravastation

72
Q

Tamoxiphen

A

Cancer
Decrease estrogen

73
Q

Leucovorin

A

Cytoprotectant
folic acid

74
Q

Oprelvekin

A

cytoprotectant
increase platelet

75
Q

Gentamicin

A

Antibiotic
Ototoxic, nephrotoxicity
Narrow TI
Avoid penicillin within hour pre/post administration

76
Q

Meropenem

A

Antibiotic
Ulcerative colitis
IM with lidocaine

77
Q

Cephalosporin

A

Antibiotic
bleeding

78
Q

Aztreonam

A

Antibiotic
dilation –> muc–> aztreonam

79
Q

Penicillin

A

Antibiotic

Interstitial nephritis, hypersensitivity
cardiac arrest

80
Q

Fluoroquiniolone

A

Antibiotic

tendinitis, photosensitive, QT prolonging

81
Q

Erythromycin

A

Antibiotic

hepatotoxic, PC, prolong QT

warfarin +dig

82
Q

Fluconzaole + Diltiazem

A

cardiac death

83
Q

Clindamycin

A

Antibiotic

fatal PC

84
Q

Vancomycin

A

Antibiotic

narrow TI, red man syndrome

85
Q

Linezolid

A

Antibiotic

short-term
serotonin syndrome
bone marrow suppressant

86
Q

Chloramphenicol

A

Antibiotic

blood dyscrasia (aplastic anemia)

87
Q

Sulfonamides

A

Antibiotic

photosensitive, hypersensitive, Steven Johnson

88
Q

Tetracyclines

A

Antibiotic

remain upright 30 min
renal failure for expired
teeth discoloration
harm bone growth

89
Q

Phenazopyridine

A

Antiseptic

orange color urine –> no UA
renal failure 2< days

90
Q

Rifampin

A

TB
orange/staining

91
Q

INH

A

TB
liver toxic - VB6 50mg
neuropathy

92
Q

Pyrazinamide

A

TB
high uric acid/joint pain

93
Q

Ethambutol

A

TB
Optic neuritis

94
Q

Famciclovir Acyclovir Valacyclovir

A

Herpes

purpura (decrease platelet
tinny red dots

95
Q

Ganciclovir

A

Cytomegaloherpes

bone marrow suppression
BIRTH DEFECT

96
Q

Oseltamivir

A

Flu

48hr of symptom

97
Q

Ribavirin

A

RSV

inhaled, EXTREME TERATOGENIC

98
Q

Amphotericin B

A

Antifungal

big infection
cardiac death
no dextrose
no amino

99
Q

Fluconazole

A

Antifungal

hepatic necrosis

100
Q

Echinocandin

A

Antifungal

drug binds to albumin

101
Q

-Quinn

A

Antimalarial

malaria
pre/post exposure

102
Q

Amebicides

A

drinking will damage liver
flush/sweating

103
Q

Lindane

A

CNS toxicity –> seizure

Pharm 2 (3 decks)

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