Exam One Flashcards

1
Q

Schedule I

A

Heronin, LSD

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2
Q

Schedule II

A

codeine, morphine, oxytocin

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3
Q

Schedule III

A

ADHD, adderall

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4
Q

Schedule IV

A

sedatives, anti-anxiety

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5
Q

Schedule V

A

cough meds

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6
Q

Which pharmacokinetic is described by the drug reaches the target cell?

A

Absorption

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7
Q

What is the serum drug level?

A

drug in bloodstream

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8
Q

What diuretic increases potassium? Which decreases?

A

Spironolactone

Hypokalemia

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9
Q

Teratogenicity

A

abnormal fetal development

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10
Q

Blood incompatibility can lead to which drug allergy?

A

Cytotoxic

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11
Q

What is the universal antidote?

A

Charcoal

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12
Q

What are common mistakes of med administration?

A

Calculation
Drug form
Route
Administration technique

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13
Q

Concerns to herbal and dietary supplements

A

Safety
Prevent patient from seeking treatment
Interaction
Lack of research
Lack of reporting their use

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14
Q

What population are meds mainly weight based?

A

Pediatric

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15
Q

Pharmacodynamics of the older population:

A

Reduced receptor site
Medication tolerance Chronic Illness Polypharmacy
Beers Criteria

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16
Q

How does cancer start?

What are causes?

A

From one abnormal cell (mutation or tumor initiation)

Radiation, Chemicals, Viruses

HORMONES PROMOTE NOT CAUSE

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17
Q

Metastasis

A

invading other tissue to other organs

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18
Q

How do meds treat cancer?

A

Interfere with replication, nutrient use/supply or genes
dosed by weight
teratogenic
hard on liver/kidney

19
Q

Which cells does drug therapy work most on?

A

rapidly dividing cells

20
Q

Cyclophosphamide

A

Oral/IV
Bladder toxicity (drink 2L)

21
Q

Cisplatin

A

Bladder/Ovarian/Testicle
IV (verify patency)
**extravasation

22
Q

Cisplatin extravasation

A

Stop and d/c
disconnect tubing
aspirate
Sodium thiosulfate antidote
Elevate

23
Q

Methotrexate

A

Prevent folic acid (teratogenic)
Lupus, rheumatoid arthritis

24
Q

Fluorouracil

A

Do not use metal to apply

25
Hydroxyurea
Oral, Sickle Cell
26
Antitumor Antibiotics
Interfere with DNA replication, can become cardiotoxic
27
Biologic Antineoplastic
Use own body to fight - stimulate body to detect and attack it.
28
Alert for frowth factor and tyrosin kinase inhibitors
SWALLOW WHOLE/DISSOLVE COMPLETELY
29
Tamoxifen
treat/reduces risk of breast cancer Oral Double glove if splitting pill DECREASES ESTROGEN - BONE MINERAL TESTING
30
Anastrozole
Breast Cancer Oral No need to double glove DECREASES ESTROGEN - BONE MINERAL TESTING
31
Cytoprotectants
Reverse effects of cancer drugs (help side effects of cancer)
32
Cytoprotectants Epoetin alfa
stim RBC, anemia
33
Cytoprotectants Filgrastim
Help WBC production
34
Cytoprotectants Leucovorin
Folic Acid for Methotrexate
35
Cytoprotectants Oprelvekin
platelete, prevent bleeding
36
Cytoprotectants Sargramostim
immune booster (WBC production)
37
Treatment N/V from chemo
Ondansetron + steroid Palonsetron Benzodiazepine
38
Treatment mucositis from chemo
chew ice before chemo
39
Treatment Infection r/t chemo
Filgrastim Sargramostim
40
Treatment bleeding r/t chemo
Thrombopoietin (Oprelyeki) Platelet Administration
41
Treatment Hyperuricemia r/t chemo
High fluid Allopurinol
42
Treatment Hand-foot related to chemo
Decrease heat/friction Ice + acetaminophen
43
Tumor Lysis Syndrome
Hyper- kalemia, phosphatemia, uricemia Hypo- magnesemia, calcemia ACIDOSIS Treat with aggressive hydration, sodium bicarbonate, allopurinol