Structures of Blood vessels and Heart Flashcards

1
Q

Order of blood vessels the blood passes through after the heart

A
Heart
Elastic arteries 
Muscular arteries
Arterioles
Capillaries
Venules
VEins
Muscular veins
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2
Q

What is the innermost layer of the blood vessels

A

Tunica intima

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3
Q

What is the middle layer of the blood vessels

A

Tunica media

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4
Q

What is the outermost layer of the blood vessels

A

Tunica adventitia

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5
Q

What does the tunica intima have lining the lumen

What does it have adjacent to this

A

Simple squamous epithelium lining the lumen

AN adjacent layer of connective tissue

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6
Q

What is the tunica media made of

A
  • Smooth (or cardiac) muscle which is mainly circular

- Varying amounts of elastin, mainly in sheets in the interspersed connective tissue

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7
Q

What does the tunica adventitia consist of

A

-connective tissue with varying amounts of interspersed elastic fibres and smooth muscle cells (mainly longitudinal)

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8
Q

What layers does the heart have

A

Endocardium (tunica intima)
Myocardium (tunica media)
Epicardium (tunica adventitia)

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9
Q

What is the difference between the tunica media in the heart vs vessels

A

In the tunica media, it consist of cardiac and not smooth muscle

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10
Q

What is the squamous epithelium in the endocardium lined by

A

Thin band of relatively loose connective tissue

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11
Q

What is the myocardium supplied by

A

Coronary vessels

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12
Q

What is the epicardium like

A

Partially dense, partially loose connective tissue

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13
Q

What is the connective tissue in the epicardium bordered with

A

Simple squamous epithelium (visceral pericardium) which forms the inner lining of the pericardial sac

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14
Q

What is pulsating blood flow met by In elastic arteries

A

Lamellae of elastin woven into the media

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15
Q

What do muscular arteries do

A

Help distribute the bulk of blood to the site of need eg to the leg muscles when cycling

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16
Q

Using a histological stain and looking at the tunica media, what does collagen look like

A

Red with few thin interspersed elastin sheets

17
Q

USing a histological stain and looking at the tunica media, what do the circular smooth muscle cells look like

A

Brown

18
Q

Using a histological stain, what does the external elastic membrane look like in the tunica media

A

Black

19
Q

What is a blood vessel with a perpendicular pattern most likely to be

A

Artery or arteriole

20
Q

Which vessels are the main site of blood pressure regulation

A

Arterioles

21
Q

How many smooth muscle cells would an arteriole have

A

1-3

22
Q

Why are there no internal elastic membranes in small arteries and arterioles

A

Because flow is not pulsating anymore

23
Q

Why do small arteries and arterioles not have vasa vasorum

A

Because their walls are small enough to be supplied by diffusion

24
Q

What do capillaries not have

A

Media or adventitia

25
Q

What do capillaries contain

A

One layer of endothelial cells

A few collagen fibres around it

26
Q

How are larger molecules transported through capillary walls

A

IN small vesicles by pinocytosis

27
Q

Difference between continuous capillaries and fenestrated capillaries

A

-Continuous= Lumen is lined by a continuous uninterrupted layer of single endothelial cells that are linked by cell-cell contacts containing tight and adherent junctions

Fenestrated= numerous pores in their endothelial cells. Therefore the barrier to the interstitial is the basement membrane

28
Q

Where are sinusoids found

A

Liver and the spleen

29
Q

What are sinusoids

A

Beds of wide capillaries with diameters of several erythrocytes. Their endothelial cells and basement membranes have holes which allow plasma to directly reach cells. This allows fast exchange of larger components

30
Q

What are pericytes

A

cells that wrap around endothelial cells throughout the body. They are essential for the regulation of blood flow and maintenance of homeostasis within the body, such as the blood-brain barrier.

31
Q

What do venules not have

A

No media and no or hardly any adventitia

32
Q

In the extremities, what are muscular arteries often accompanied by and what does this do (vein-artery-vein triplets)

A

Accompanied by veins on either side so that the pulsations slightly compress the veins, driving the blood towards the heart due to the valves

33
Q

What does the portal vein do

A

Links the capillary beds of the digestive system and spleen directly to the capillary bed (sinusoids) of the liver

34
Q

What is an anastomosis

A

Direct link between an artery or vein without a capillary bed in between

35
Q

How does fluid enter the lymphatic system

A

Blood circulation is slightly leaky and so fluid leaves mainly in the capillary beds.

36
Q

Why does fluid leave the capillary beds

A

Because of blood pressure and osmotic differences between blood and interstitial fluid

37
Q

Pathway of fluid before it goes into lymphatic vessels and back into the blood circulation

A

Fluid leaks out, and drains from the tissues as lymph via lymph vessels which feed as afferent lymphatics into lymph nodes. Lymph is checked for antigens in lymph nodes. After checks, the lymph enters the lymphatic ducts, which empty into the subclavian veins.