structure and function of nucleic acids Flashcards

1
Q

summarise the importance of nucleic acids

A

-Important macromolecule in the nucleus of cells
-Storage and expression of genetic information

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2
Q

what are nucleosides?

A

building blocks of nucleic acids like DNA and RNA.

They consist of a five-carbon sugar molecule, known as a pentose, attached to a nitrogenous base

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3
Q

what are the 2 nucleosides?

A

Deoxyribose
Ribose

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4
Q

Deoxyribose describe

A

pentose sugar has a hydrogen atom attached to carbon number 2

monomers of DNA

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5
Q

ribose describe

A

hydroxyl group (-OH) attached to carbon number 2

Ribose-containing nucleotides, known as ribonucleotides, are the monomers of RNA (Ribonucleic Acid).

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6
Q

Nucleoside – part 2/2

A

consist of heterocyclic ring structures with carbon and nitrogen atoms.

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7
Q

In DNA what are the 4 bases

A

AT
CG

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8
Q

In dna which are the purines

A

adenine and guanine

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9
Q

in dna which are the pyrmadines

A

thymine and cytosine

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10
Q

in RNA what are the bases

A

AG (PURINES)
UC( PYRAMDINES)

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11
Q

Nucleotide – part 1/3

A

molecules consisting of three main components: a five-carbon sugar (pentose), a nitrogenous base, and one or more phosphate groups.

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12
Q

What are the two pentose suagrs found in nucleotides

A

Deoxyribose
Ribose

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13
Q

The bonding between nitrogenous bases in DNA is crucial why?

A

maintaining the structure and stability of the DNA molecule.

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14
Q

The bonding between nitrogenous bases in DNA is crucial why? (2)

A

hydrogen bonds between complementary base pairs help keep the two DNA strands at a fixed distance from each other along the entire length of the double helix

specific pairing of A-T and G-C bases allows the bases to fit together exactly, forming stable hydrogen bonds. This precise pairing ensures the accuracy of DNA replication

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15
Q

Erwin Chargaff determined that

A

amount of adenine (A) = amount of thymine (T)
amount of cytosine (C) = amount of guanine (G)

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16
Q

Nucleosides- Phosphate (PO4):

A

Phosphate groups can form high-energy bonds, known as phosphoanhydride bonds.

Nucleotides, composed of a phosphate group, a sugar molecule, and a nitrogenous base, contain one or more phosphate groups.

17
Q

summarise cAMP

A

Secondarily messenger
Facilitates cellular glucagon and adrenaline uptake
Activates protein kinases
Regulates ion channels

18
Q

how are nucleotides linked?

A

linked by 3’ to 5’ phosphodiester bonds

19
Q

what is a nucelosdie

A

Base + deoxyribose

20
Q

what is a nucelotide?

A

= Nucleoside + phosphate

21
Q

what is a nuelcic acid

A

Polymer of nucleotides

22
Q
A