structure and function Flashcards
layers of dermis
keratin
granular
prickle cell
basal
which layer of the dermis has odland bodies and high lipid content
granular layer
which layer contains stem cells
basal
which layer is usually one cell thick
shape of cells?
basal
cuboidal
what layer contains langergans cells?
prickle cell
skin immune system
langerhans cells
where are eccrine glands
whole skin surface
what glands are dormant pre puberty
sebaceous
which glands are in the axillae and groin
what are they dependent upon?
apocrine
androgen dependent
where are there lots of meissners corpuscles
fingertips
what are merkel cells
mechanoreceptors
what do keratinocytes produce that can directly kill pathogens
AMPs
what cells secrete collagen
fibroblasts
what are the large granules contained in langerhans cells called
birbeck granules
direct skin manifestations of obesity
acanthosis nigricans skin tags (acrochordons) hirsutism, acne hidradenitis suppuratira - chronic inflammatory disease where boils and abscesses form and scar in apocrine areas androgenic alopecia
the skin is involved in vitamin D metabolism
.
MHC does class 1 present endogenous or exogenous antigen?
endogenous
class 2 presents exogenous antigen
what do plasmacytoid dendritic cells produce
in what type of skin is it found?
IFNalpha
found in diseased skin
main type of T cells in the dermis
CD8+ T cells
T cells in the dermis
CD4+ and CD8+
TH1
psoriasis
TH2
atopic dermatitis
