structure and function Flashcards

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1
Q

layers of dermis

A

keratin
granular
prickle cell
basal

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2
Q

which layer of the dermis has odland bodies and high lipid content

A

granular layer

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3
Q

which layer contains stem cells

A

basal

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4
Q

which layer is usually one cell thick

shape of cells?

A

basal

cuboidal

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5
Q

what layer contains langergans cells?

A

prickle cell

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6
Q

skin immune system

A

langerhans cells

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7
Q

where are eccrine glands

A

whole skin surface

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8
Q

what glands are dormant pre puberty

A

sebaceous

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9
Q

which glands are in the axillae and groin

what are they dependent upon?

A

apocrine

androgen dependent

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10
Q

where are there lots of meissners corpuscles

A

fingertips

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11
Q

what are merkel cells

A

mechanoreceptors

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12
Q

what do keratinocytes produce that can directly kill pathogens

A

AMPs

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13
Q

what cells secrete collagen

A

fibroblasts

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14
Q

what are the large granules contained in langerhans cells called

A

birbeck granules

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15
Q

direct skin manifestations of obesity

A
acanthosis nigricans 
skin tags (acrochordons)
hirsutism, acne
hidradenitis suppuratira - chronic inflammatory disease where boils and abscesses form and scar in apocrine areas 
androgenic alopecia
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16
Q

the skin is involved in vitamin D metabolism

A

.

17
Q
MHC
does class 1 present endogenous or exogenous antigen?
A

endogenous

class 2 presents exogenous antigen

18
Q

what do plasmacytoid dendritic cells produce

in what type of skin is it found?

A

IFNalpha

found in diseased skin

19
Q

main type of T cells in the dermis

A

CD8+ T cells

20
Q

T cells in the dermis

A

CD4+ and CD8+

21
Q

TH1

A

psoriasis

22
Q

TH2

A

atopic dermatitis