Skin cancer Flashcards
acral lentiginous melanoma
common in what type of skin?
where on the body?
dark skin
palms and soles
the most common type of melanoma
superficial spreading melanoma
the cells tend to stay in the epidermis for a long period (months/decades) and later become invasive
most aggressive form of melanoma
nodular
keratoacanthomas - where are they believed to origionate from?
neck of the hair follicle
most UV we are exposed to is which type?
UVA
but UVB is 1000x more damaging
what is the UV signature mutation
pyrimidine dimer
melanoma depth
4mm prognosis?
4mm - 50% 5 yr survival
what cells do BCCs arise from
keratinocytes
what layers do SCCs arise from
supra basal layers
which may be painful, BCCs or SCCs
SCCs
visible arborising blood vessels
BCC
warty/crusted growth
SCC
what may a SCC arise from?
actinic keratosis
early onset/multiple BCCs
other features of this disease
gorlins
jaw cysts
palmar pits
