Structure and Function Flashcards
Triune Brain
- Paul McLeod developed in late 1940s of the structures of the brain (not true)
- Survival Brain = reptillain
- Emotional Brain = Limbic
- Thinking Brain = Neo-corte
Hindbrain
- Primitive (earliest) level of the brain
- Continuation of brain and spinal cord
- Part of brainsteam: Imports vital functions
- Damage can be catastrophic as it supports life dependent functions
Brainstem
- Total of hindbrain and midbrain
3 main structures of the Hindbrain
- Medulla
- Pons
- Cerebellum
Medulla
- Vital role in supporting repiration and managing heart rate
- Part of the path for sensory and motor nerve tracks that come through the spinal cord from the brain
Pons
- Releases sensory information between the cerebral cortex and cerebellum
- Supports regulation of sleep and helps control respiration
- Huge problems if damaged
- Sits above Medulla
Cerebellum
- Involved in movement, learning and sequencing
- Physical damage can result in poor coordination and uncoordinated movements (walking can be problematic - movements you don’t have to consciously think about)
- Alcohol has been seen to cause temporary distruption
What is this?

Hindbrain
Midbrain
- Sensory and motor neurons running through it
- Involved in consciousness, sleep, attention
4 main components of the Midbrain
- Reticular Formation
- Superior Colliculus
- Inferior Colliculus
- Substantia Nigra
Reticular Formation
- Runs from the hindbrain to forebrain and has both sensory and motor ascending and descending fibres
- Taking in information and integrating it and also then sending information on
Superior Colliculus
- Deals with eye movements, saccadic eye movements, and for that reason, receives input from the retina and from the visual cortex
- Particularly important in fast eye movements, visual reflexes and visual field tracking.
Inferior Colliculus
- Synapsing point for sound that has both crossed and uncrossed auditory fibres.
- That then continous information into a part of the thalamus that is involved in processing auditory information.
Substanita Nigra
- Key part of the dopaminergic system that include control, movement and patterns of movement coordination.
- When there is disruption, you can see effects, for example, in Parkinson’s disease, where you can see the effects on motor coordination.
Forebrain
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7 main components of the Forebrain
- Thalamus
- Hypothalamus
- Hippocampus
- Amygdala
- Cingulate Cortex
- Limbic System
- Basal Ganglia
Thalamus
- Relay station for organising sensory information and routing them to further areas within the cortex
- Made up of a number of different nuclei (cluster/group of cell bodies)
- Damage/distruption in this area plays a role in hallucinations and schizophrenia
3 components of the Thalamus
- Lateral geniculate nuclei
- Medial geniculate nuclei
- Ventral posterior nuclei
Lateral geniculate nuclei
- Visual relay station
Medial geniculate nuclei
- Auditory relay station
Ventral posterior nuclei
- Somatosensory relay station
Hypothalamus
- Responsible for hormone secretion, relating to sexual development, sexual behaviour, metabolism and stress responses
Hippocampus
- Involved in memory
- Forming and retrieving memories - especially spatial learning
Amygdala
- Involved in emotional behaviours - e.g. fear, agression etc
- Involved in emotional responses, both with and without higher brain regions or the cortex being involved
- Sometimes linked with quick unconscious emotional responses
Cingulate Cortex
- Realetd to emotion, regulation of responses as part of motion and memory
- Anterior singular cortex - error detection in conflict monitoring
- Posterior cingulate cortex may be more involved in attention
Main structures of Limbic System
- Hoppocampus
- Amygdala
- Cingulate Cortex
Basal Ganglia
- Most important components:
- Caudata Nucleus
- Putamen
- Substantia Nigra
- Important in controlling movements, eye movements (such as posture, reaching and grasping), skill learning and rewards systems
What is this?
- Pons
What is this?
- Cerebellum
What is this?
- Brain Stem
What is this?
- Thalamus
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- Hypothalamus
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- Hippocampus
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- Amygdala
What is this?
- Cingulate Cortex
What is this?
- Basal Ganglia
Areas of the cortex
- Frontal Lobe
- Parietal Lobe
- Temporal Lobe
- Occipital Lobe
Frontal Lobe
- Motor activity, speech, planning and impulse control
- Includes areas such as:
- Prefrontal cortex
- Frontal eye fields
- Premotor Cortex
- Primary motor cortex
- Broca’s area
Frontal eye fields
- Control of visual attention and eye movements
Premotor Cortex
- Uses information from other regions to control movement and prepare our movements
Primary Motor Cortex
- Intiate and coordinated movement
Broca’s area
- Important for production of language
- Helped us understanding the specific regions can be very important in supporting particular behaviours or abilities
What area of the brain is this?
- Frontal Lobe
Cortical Organisation
- The brain represents the body is called somatotopic organization, it is an orderly way of arranging representation and it has a spatial component, but the spatial representation is not one that reflects what you would observe from externally viewing the body.

Frontal Lobe - Dorsolateral Prefrontal cortex and Medial Prefrontal cortex
- Both involved in complex executive behaviours
Parietal Lobe
- Intergrating sensory information and spatial tasks
- Contains superior parietal lobule, the inferior parietal lobule, somatosensory cortex, and precuneus cortex, which is hard to study and involved in memory, particularly episodic memory, visual-spatial processing, etc.
Temporal Lobe
- Auditory perception, memory and emotion
4 main components of the Temporal Lobe
- Primary Auditory Cortex
- Wernicke’s Area
- Inferior Temporal Gyrus
- Middle Temporal Gyrus
Primary Auditory Cortex
- Responsibe for processing sounds
- Damage results in behaviour called agnosia - inability to recognise specific sounds or objects
Wernicke’s Area
- Comprehension of language
Middle Temporal Gyrus
- Support for semantic memory processing, language processing
Inferior Temporal Gyrus
- Association for visual perception, mental imagery, and intergrating information from different senses
Corpus Callosum
- White matter tracts that connect the right and left hemisphere
- Allows information to move between hemispheres
What is this?
What is this?
- Broca’s Area
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What is this?
- Premotor Cortex
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- Primary Motor Cortex
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- Occipital Lobe
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- Parietal Lobe
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- Temporal Lobe
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- Corpus Callosum
What is this?
- Middle and Inferior Temporal Gyrus
What is it?
- Superior Temporal Gyrus
What is this?
- Wernicke’s Area
Working memory - interaction of Frontal and Posterior Cortical Areas
- Involves short-term storage maintenance of information when performed in the face of processing information at the same time.
- In a simple form, working memory is memory that we work with it supports our moment-to-moment cognition
- e.g. telling someone a story and using facial expression to work out if they know what we are talking about - if not expanding on it to gain their understanding
Single-unit recording
- To study single neurons using micro-electrode
- Very sensitive, detects 1 millionth of a volt
- Localised technique
Event-related potentials (ERPs)
- Electroencephalogram (EEG) records brain (electrical) activity at the surface of the scalp but ‘noise’ obscures stimulus-related activity
- Present same stimulus numerous times, then average the effect on EEG output
- High temporal resolution (ms) but low spatial resolution
- Exactly where the recorded activity is happening is slightly less clear in EEG work, technique is low and spatial resolution.
- Measures are taken at specific points, but the surface recordings can let you know exactly where that activity is happening on the where is being measured
Positron emission tomography (PET)
- (tiny amounts of) radioactive liquid injected into body, gathers in brain’s blood vessels
- Active areas attract the liquid, scanner then creates image of activity based on the emitted positrons
- Poor temporal but reasonable spatial resolution
- Involves use of a tracer, radioactive tracer. You can detective its emissions, which is attached to biologically active molecule, which is a glucose analogue (glucose can cross the blood-brain barrier) this analogue is taken up by active cells, unable to fully break it down. That enables us to see what regions are engaged in metabolic activity. So that is what bits of the brain are becoming active in response to a task.
- So you can see where glucose is being requested is initially by regions.
Magnetic Resonance Imaging (MRI and fMRI)
- Radio waves excite atoms in the brain producing magnetic chnages detected by magnet
- Chnages detected by computer which gives 3D image
- Blood oxygenation in the brain can also be detetcted to indicate functional changes
- More spatial and temporal resolution than PET
Transcranial Magnetic Stimulation (TMS)
- Coil delivers pulse which gives area temporary ‘lesion’
- Allows us to target particular areas of the brain by passing electricity through coils in a 1D can create a magnetic field. Apply that short current or pulse to a particular area and create the effects of what is known as a temporary lesion and that can hyperpolarize are depolarized cells
- Results can be excitatory or inhibitory, but essentially what we’re doing is interfering with the electrical activity of cells
- Allows us to test predictions
- Technique that allows us to go beyond the observation and correlation
Lesion Studies
- Studies that are largely carried out and non-humans, still ethical issues of testing in animals
- There is different types of lesions that can be done.
- Experimental ablation: where part of the brain is removed or damaged through purpose-built.
- Radiofrequency ablation: where part of the brain is sucked out, or where part of the brain is lasered out
Limitations of Experimental Cognitive Psychology
- Laboratory research lacks ecological validity
- Measures such as RT, accuracy, are indirect
- Need understanding of brain function
- Written theories can be poorly defined
- Problem of individual differences
- No one over-arching cognitive architecture accepted
Experimental Cognitive Psychology
- Experiments carried out on healthy individuals under controlled laboratory conditions
- Compare one condition with another (or others), then test resulting data statistically
- Nearly all cognitive psychology research carried out in this way initially
- Played major role in development/testing of theories -
- Relatively well developed methods which also influence other areas of psychology
Cognitive Neuropsychology
- Study of patterns of cognitive performance, (intact and impaired) exhibited by brain-damaged individuals
- To provide knowledge about normal human cognition - complexities revealed when system malfunctioning - e.g. patient HM
Patient HM
- He had hippocampal removal as a result of medial temporal lobe removal, there was an attempt to deal with epilepsy.
- He was able to recall an a gradient manner the time before he surgery, but no episodic memory following that.
- He could still do form new short-term memory, but not anything that would be a little lasing.
- He revealed a number of complexities about memory but could recall things from his past without being able to create new memories and that therefore indicated certain regions are involved, certain regions damaged in it HM surgery were important for making new memories.
Cognitive Neuropsychology - Assumes
- Functional & anatomical modularity: cognitive systems domain-specific, in specific identifiable areas
- Uniformity of functional architecture across individuals
- Idea that what we can conclude from observing an individual case study, we’ll generalize across people. When really people differ.
- Subtractivity: impairments cannot add to systems
- The idea that brain damage will remove aspects of functioning, but it won’t lead to new functions, but that’s not necessarily as true as it seems
Cognitive Neuropsychology - Limitations
- Typically, damage is extensive
- Becomes hard to attribute function to a specific area if damages, diffuse effects, or the one area of time.
- Diverse patients with broadly similar brain damage
- Sometimes damage to the same area can show lots of different difficulties.
- Surprisingly, damage in different areas can produce similar cognitive profiles that’s rarer but does happen.