Structural Heart Disease Flashcards
Cardiac cycle
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Tetralogy of Fallot
Widen aorta (overriding)
Narrow pulmonary artery (stenosis)
Thicken right ventricular wall (hypertrophy)
Septal defect
AS causes
Rheumatic heart disease
Calcium build up
Hypertension
LDL
AS pathophysiology
Endocardial injury
Inflammation
Calcification
Stenosis
AS investigations
Transthoracic echocardiogram
Chest X ray
AS management
Aortic valve replacement - symptomatic, asymptomatic with LVEF <50%
AR causes
Rheumatic heart disease
Infective endocarditis
Valve stenosis
AR pathophysiology
Trauma, IE lead to rupture of leaflets in acute cases
RF, bicuspid aortic valves lead to retraction of leaflets and leak
AR investigation
Transthoracic echocardiogram
Chest X-ray
AR management
Acute - ionotropes/vasodilator and valve replacement
Chronic asymptomatic- if LV function is normal can be managed with drugs
Chronic symptomatic- valve replacement with vasodilator
Prevention is key
MS causes
Rheumatic fever
SLE
Rheumatoid arthritis
Carcinoid syndrome
MS pathophysiology
Insult to endometrium lead to formation of infiltrates, calcification and stenosis
MS investigation
ECG
Transthoracic echocardiogram
MS management
Asymptomatic- none
Severe asymptomatic- none, adjuvant balloon valvotomy
Severe symptomatic- diuretic, balloon valvotomy, valve replacement and adjunct b blocker
MR cause
Acute
- mitral valve prolapse
- rheumatic heart disease
- infective endocarditis
Chronic
- rheumatic heart disease
- SLE
- scleroderma
MR pathophysiology
Disruption of any part of mitral leaflets, perforations etc lead to abnormal reversal of blood
MR investigation
ECG
Transthoracic echocardiogram
MR management
Acute - emergency surgery with diuretics and intraaortic balloon counterpulsation
Chronic asymptomatic - ACE inhibitor, beta blocker. If LVEF less than 60% - surgery
Chronic symptomatic - surgery plus medicine. If LVEF less than 30% then intraaortic balloon counterpulsation
Dilated cardiomyopathy cause
Heart valve disease
Myocarditis
Autoimmune
Primary with and without family history