Structural and Functional Organization of the Endocrine System Flashcards

1
Q

Major glands of the endocrine system

A

THOAPPP
Thyroid
Hypothalamus
Ovaries (and Testes)
Adrenals
Pituitary
Parathyroid
Pancreas
Pineal

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2
Q

A target cell will have how many receptors for a particular hormone?

A

2,000-100,000

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3
Q

two types of hormone compositions

A

lipid soluble vs water soluble

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4
Q

what are the lipid soluble hormones

A

steroid, thyroid, and nitric oxide

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5
Q

What are the water soluble hormones

A

Amino acids

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6
Q

how do hormones influence their target cells?

A

by chemically binding to specific protein receptors

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7
Q

what are hormone receptors

A

protein markers on a cell that allow a specific hormone to bind and be recognized.

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8
Q

what structure is known as the master switchboard?

A

the hypothalamus

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9
Q

What is the master gland of the body?

A

the pituitary gland

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10
Q

how many hormones does the hypothalamus secrete?

A

nine

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11
Q

how many hormones does the pituitary secrete?

A

seven

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12
Q

what attaches the pituitary gland to the hypothalamus?

A

infundibulum

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13
Q

what is the term for the blood vessels that connect the capillaries in the hypothalamus to capillaries in the pituitary? (the road for hormones)

A

Hypophyseal Portal Veins

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14
Q

GnRH releases what?

A

FSH and LH

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15
Q

Growth hormone releasing hormone stimulates what?

A

HGH and IGF

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16
Q

Growth hormone-inhibiting hormone inhibits what?

A

inhibits HGH and IGF

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17
Q

Thyroid releasing hormone stimulates what?

A

TSH

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18
Q

Prolactin releasing hormone stimulates what?

A

PR

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19
Q

prolactin inhibiting hormone inhibits what?

A

PR

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20
Q

Corticotropin releasing hormone stimulates what?

A

ACHT

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21
Q

Where do both lobes of the pituitary gland rest?

A

in the hypophyseal fossa, a cup shaped depression in the sphenoid bone

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22
Q

What is a hormone that stimulates an endocrine gland to grow and secrete its hormones?

A

a Tropic Hormone

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23
Q

What are the hormones of the anterior pituitary?

A

hGH
TSH
FSH
LH
PRL
ACTH
MSH

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24
Q

which hormone promotes synthesis and secretion of insulinlike growth factor

A

hGH

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25
what are proteins secreted mainly by cells in the liver, but also by cells in skeletal muscles, cartilage, bones, and other tissues in response to stimulation of hGH
IGFs
26
what are two hypothalamic hormones that control secretion of hGH?
Growth Hormone-Releasing Hormone and Growth Hormone-Inhibiting Hormone
27
what stimulates the synthesis and secretion of thyroid hormones by the thyroid gland? what releases it?
Thyroid Stimulating Hormone (TSH), released by Anterior Pituitary
28
which hormone initiates and maintains milk production by the mammary glands?
Prolactin
29
What suppresses release of prolactin most of the time?
Prolactin inhibiting protein (PIH)
30
what stimulates release of Prolactin Releasing Hormone (PRH)
pregnancy, (very high levels of estrogen)
31
what controls the production and secretion of hormones called Glucocorticoids by the cortex of the adrenal gland?
Adrenocorticotropic Hormone (ACTH)
32
This hormone of the anterior pituitary is very little in humans and excessive amount can cause darkening of the skin?
Melanocyte Stimulating Hormones (MSH)
33
the _______ contains axons and axon terminals of neurosecretory cells whose cell bodies are in the hypothalamus.
posterior pituitary
34
two hormones that are stored and released (not synthesized) by the posterior pituitary?
Oxytocin Antidiuretic Hormone (ADH)
35
what hormone released in large quantities enhances contraction of the smooth muscle cells in the walls of the uterus as well as stimulates milk ejection?
oxytocin
36
what hormone casues the kidneys to retain more water, decreasing water loss through sweating, and can constrict arterioles causing an increase in blood pressure?
Antidiuretic Hormone (ADH)
37
in the absence of ADH, urine output can increase to what in a day?
20 L
38
what is the function of the thyroid gland?
to run the BMR
39
what is BMR?
the rate at which the body uses energy while at rest to keep vital functions going, such as breathing, keeping the heart beating, and keeping the body warm.
40
what makes up most of your thyroid gland?
Spherical sacs called thyroid follicles
41
what produces Thyroxine (T4) and Triiodothyronine (T3) and lines the walls of thyroid follicles?
follicular cells
42
what plays an important role in the maintenance of normal body temperature?
Thyroid Hormones
43
what stimulates protein synthesis, use of glucose and fatty acid for ATP, increases breakdown of triglycerides and enhance cholesterol excretion?
thyroid hormones
44
together with hGh and insulin, _______ stimulates body growth.
thyroid hormones
45
what is released by the parafollicular cells and inhibits the action of osteoclasts?
Calcitonin
46
what are the cells that break down bone?
osteoclasts
47
what cells in the parathyroid gland secrete PTH?
Chief cels
48
what is the major regulator of calcium, magnesium, and phosphate ions in the blood?
PTH
49
what hormone increases the number of osteoclasts?
PTH
50
what are the three changes in the kidney produced by PTH?
slows calcium, magnesium loss from blood into urine. increases loss of phosphate in urine promotes formation of Calcitrol
51
which cells secrete glucagon in the pancreas?
Alpha
52
release of glucagon is stimulated by _______ division of the autonomic nervous system.
sympathetic
53
which cells secrete insulin in the pancreas?
Beta
54
release of insulin from the pancreas is stimulated by the _____ division of the ANS.
parasympathetic
55
what promotes the uptake of amino acids into the body cells and increases the synthesis of protein and fatty acid within the cells?
insulin
56
what are the three zones of the adrenal cortex?
outer (Glomerulosa) middle (Fasciculata) inner (Reticularis)
57
which zone of the adrenal cortex release hormones called mineral corticoids (e.g. Aldosterone)
Glomerulosa
58
which zone of the adrenal cortex releases hormones called glucocorticoids (e.g. Cortisol)
Fasciculata
59
which zone of the adrenal cortex releases androgens?
the inner zone (Reticularis)
60
what is the major mineral corticoid of the zona glomerulosa?
aldosterone
61
aldosterone regulates which two mineral ions?
sodium and potassium Sodium from the urine into the blood stimulates excretion of K into urine
62
what helps adjust blood pressure, and blood volume and promotes excretion of H+ in the urine?
aldosterone. part of the renin-angiotensin, aldosterone pathway.
63
what is the action of glucocorticoids (such as cortisol) in the zona fasciculata?
protein breakdown glucose formation breakdown of triglycerides anti inflammatory affects depression of immune system