Stroke Flashcards

1
Q

Define stroke

A

acute onset of focal neurological symptoms & signs due to disruption of blood supply

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2
Q

What are the two types of stroke?

A

Haemorrhage

Ischaemic

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3
Q

Describe a haemorrhagic stroke

A

Bleeding occurs inside or around the brain tissue due to a ruptured vessel

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4
Q

What is the biggest risk factor for a haemorrhagic stroke?

A

Hypertension - arteriosclerosis leads makes the vessel more likely to rupture. Weaknesses in vessel walls due to structural abnormalities like aneurysm or inflammation also can cause a HS.

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5
Q

Define ischaemic stroke

A

A clot blocks blood flow to an area of the brain

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6
Q

What is the difference between a thrombotic and embolic ishchaemic stroke?

A

thrombotic - clot blocking the artery is at the site of occlusion
embolic - clot blocking the artery has travelled distal to the site of origin

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7
Q

What is the third cause of ischaemic stroke?

A

Hypo perfusion - due to reduced flow of blood a stenosed artery will cause the stroke rather than an occluded one

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8
Q

State five non-modifiable risk factors for stroke

A
  • age
  • gender
  • family history
  • race
  • previous stroke
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9
Q

State some modifiable risk factors for stroke

A
  • hypertension
  • hyperlipidaemia
  • smoking
  • diabetes
  • AF
  • TIA
  • Diabetes
  • Alcohol Excess
  • Obesity
  • Physical Inactivity
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10
Q

Name a few rare cases of stroke

A
  • vasculitis
  • genetics
  • -
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11
Q

What are the three key steps in stroke management?

A
  1. Thrombolysis/Thrombectomy to reverse damage
  2. Identification of stroke type and prevention of another
  3. Neuroplasticity - rehabilitation & assessment
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12
Q

What is the key difference between a stroke and its mimics?

A

Mimics do not have interrupted blood flow

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13
Q

State five stroke mimics

A
  • hypoglycaemia
  • seizure
  • migraine
  • brain tumour
  • functional hemiparesis (pretend stroke)
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14
Q

How is the type of stroke determined?

A

By a history, examination & brain imaging (CT or MRI)

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15
Q

How are investigations directed in ischamic strokes?

A

To find whether it is thrombotic or embolic - blood tests, hypertension or other reasons for arterial disease

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16
Q

What are the two types of embolism?

A

Atheroembolism & Cardioembolism

17
Q

Describe atheroembolism, what tests are done?

A

From a thrombus forming on a plaque, infants the same side as the affected carotid artery - carotid scanning, MR angiogram of aortic arch

18
Q

Describe cardioembolism, what tests are done?

A

Embolism from a clot formed in the heart, infarcts in more than one arterial territory - ECG, mural thrombus? LVH, ECHO

19
Q

Describe thrombolysis

A
  1. blood clot
  2. tPA infected IV
  3. blood clot dissolves
  4. restored blood flow
20
Q

Describe thrombectomy

A

catheter inserted into a large vessel to pull the clot back

21
Q

What drugs should be administered after a stroke?

A

antiplatlet - aspirin & dipyridamole or clopidogrel
statins
hypertension/diabetes management

22
Q

If a stroke was due to AF what should be given?

A

Anticoagulants - Rivaroxaban, Warfarin, Dabigatran

23
Q

Post stroke what hypertension drug is given?

A

Perindorpil

24
Q

When is surgical management of a stroke required?

A

Haematoma evacuation, relief of cranial pressure or carotid endarterectomy - cleans inside the arteries

25
Q

What is a TIA?

A

Transient Ischamic Attack - neurological symptoms due to occlusion that resolves rapidly